Nanomedicine in Central Nervous System Injury and Repair

Nanomedicine in Central Nervous System Injury and Repair

First published on November 11, 2017

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  • eBook ISBN: 9780128123829
  • Hardcover ISBN: 9780128123812

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Nanomedicine in Central Nervous System Injury and Repair (IRN), Volume 137, the latest release in the International Review of Neurobiology series presents comprehensive chapters that cover a broad range of topics, including, but not limited to, how Diabetes exacerbates methamphetamine induced blood-brain barrier breakdown, edema formation, oxidative stress and myelin damage, and how Focal blast brain injury induces rapid edema formation, blood-brain barrier breakdown and intensive cellular damage. In addition, the Neuroprotective effects of a multimodal drug cerebrolysin are explored, as is how Nanowired cerebrolysin potentiates neuroprotective effects of histamine H3 receptor inverse agonist and antagonist with partial H4 agonist in Alzheimer's Disease. This series reviews current knowledge and understanding on how to repair the damaged spinal cord and brain with nanomedicine, detailing new therapeutic advances and providing a starting point for researchers and practitioners entering the field.

Key Features

  • Provides cutting-edge research on the damaged spinal cord and brain
  • Presents new therapeutic advances
  • Reviews current knowledge and understanding


Pre-clinical scientists, clinicians and physicians

Table of Contents

  • 1. Current Strategies for the Delivery of Therapeutic Proteins and Enzymes to Treat Brain Disorders
    J.T. Duskey, D. Belletti, F. Pederzoli, M.A. Vandelli, F. Forni, B. Ruozi, G. Tosi1
    2. Impact of inflammation on the blood-neural barrier and blood-nerve interface: from review to therapeutic preview
    Stephen D. Skaper
    3. Intravenous administration of Functionalized Magnetic Iron Oxide Nanoparticles does not induce CNS injury in the rat. Influence of spinal cord trauma and Cerebrolysin treatment
    Preeti K Menon, Aruna Sharma, José Vicente Lafuente, Dafin F Muresanu, Zoraida P. Aguilar, Y. Andrew Wang, Ranjana Patnaik, Herbert Mössler, Hari S Sharma
    4. Histaminergic Receptors Modulate Spinal cord Injury induced neuronal Nitric Oxide Synthase Upregulation and Cord Pathology. New Roles of Nanowired drug delivery for Neuroprotection
    Hari Shanker Sharma, Ranjana Patnaik,  Dafin F Muresanu, José Vicente Lafuente, Asya Ozkizilcik, Z Ryan Tian, Ala Nozari, Aruna Sharma
    5. Nanoformulation, a useful therapeutic strategy for improving neuroprotection and the neurorestorative potential in experimental models of Parkinson’s Disease
    Lafuente JV1,  Requejo C, Carrasco A, Pomposo I, Bengoetxea H
    6. Novel treatment strategies using TiO2 nanowired delivery of Histaminergic drugs and antibodies to tau with cerebrolysin for superior Neuroprotection in the pathophysiology of Alzheimer’s disease
    Aruna Sharma, Preeti K Menon, Ranjana Patnaik, Dafin F Muresanu, José Vicente Lafuente, Z Ryan Tian, Asya Ozkizilcik, Rudy J Castellani, Herbert Mössler

Product details

  • No. of pages: 182
  • Language: English
  • Copyright: © Academic Press 2017
  • Published: November 11, 2017
  • Imprint: Academic Press
  • eBook ISBN: 9780128123829
  • Hardcover ISBN: 9780128123812

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