Nanoengineering in Musculoskeletal Regeneration

Nanoengineering in Musculoskeletal Regeneration

1st Edition - May 8, 2020

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  • Editor: Mehdi Razavi
  • Paperback ISBN: 9780128202623
  • eBook ISBN: 9780128202630

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Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of the therapeutic pipeline—from biomedical discovery to clinical implementation—aimed at improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus, and bone. Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues.Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore, or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction, and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation.

Key Features

  • Provides broad coverage in all research areas focused on the applications of nanotechnology in musculoskeletal regeneration
  • Offers useful guidance for physician-scientists with expertise in orthopedics, regenerative medicine, bioengineering, biomaterials, nanoengineering, stem cell biology, and chemistry
  • Serves as a practical reference for many disciplines, including bioengineering, biomaterials, tissue engineering, regenerative medicine, musculoskeletal regenerative medicine, and nanomedicine


Basic and clinical researchers focused on the application of nanotechnology in musculoskeletal regeneration, also bioengineers. Graduate students in the field of regenerative medicine

Table of Contents

  • 1. Challenges toward musculoskeletal injuries and diseases
    Ge Li, Wanting Niu
    2. Nanobiomaterials in musculoskeletal regeneration
    Sara Tabatabaee, Mohammed Najafi-Ashtiani, Ali Mousavi, Nafiseh Baheiraei
    3. Drug delivery nanosystems for musculoskeletal regeneration
    Maryam Ghaffari, Fatholah Moztarzadeh, Saeid Mollazadeh-Bajestani
    4. Nanotechnology in gene therapy for musculoskeletal regeneration
    Shirin Nour, Behzad Bolandi, Rana Imani
    5. Bioprinting technology for musculoskeletal regeneration
    Farzaneh Khamseh, Shahin Bonakdar, Mohammad Hossein Alaei, Soheila Pourkhodadad
    6. Nanoengineering of stem cells for musculoskeletal regeneration
    Tina Navaei, Saeedeh Hasani, Atefeh Derakhshani
    7. Nanotoxicity and regulatory aspects in musculoskeletal regeneration
    Ronghui Du, Wanting Niu, Hao Hong, Shuxian Huo
    8. Musculoskeletal regenerative nanomedicine: Current therapies, translational hurdles, and future directions
    Maryam Tajabadi, Hamideh Barghamadi, Hanif Goran Orimi, Mahnaz Gholami, Zahra Pasandideh

Product details

  • No. of pages: 290
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: May 8, 2020
  • Imprint: Academic Press
  • Paperback ISBN: 9780128202623
  • eBook ISBN: 9780128202630

About the Editor

Mehdi Razavi

Dr. Mehdi Razavi is Assistant Professor of Medicine, Materials Science and Engineering, and BiionixTM (Bionic Materials, Implants & Interfaces) Cluster at University of Central Florida (UCF) since September 2019. Prior to his current appointment, he was a Postdoctoral Research Fellow in Regenerative Medicine with the Interventional Regenerative Medicine and Imaging Laboratory at Stanford University School of Medicine from September 2016 to September 2019. Before that he was a Postdoctoral Research Fellow in Biomaterials with the Brunel Centre for Advanced Solidification Technology (BCAST) in Institute of Materials and Manufacturing and Brunel Institute for Bioengineering (BIB) at Brunel University London from May 2015 to August 2016. He was also a Research Scholar in Biomaterials and Tissue Engineering with the School of Materials Science and Engineering, Helmerich Advanced Technology Research Center (HRC), at Oklahoma State University from July 2013 to April 2014 and an Adjunct Faculty with the Dental Materials Research Center, at Isfahan University of Medical Sciences from September 2014. He holds a PhD in Biomaterials from Isfahan University of Technology, awarded in August 2014, MSc in Materials Engineering from Isfahan University of Technology, awarded in February 2011 and a BSc in Materials Engineering from Isfahan University of Technology, awarded in September 2008. As his research honors, Isfahan University of Technology awarded him “The Best PhD Thesis”; and in June 2019, Stanford University awarded him “Poster Winner” of the 100+ posters presented at Bio-X. His research interests are mainly on Biomaterials, Nanomedicine, Tissue Engineering and Regenerative Medicine, Stem Cells, Orthopedic Implants and Bone scaffolds, Drug/Gene Delivery Systems, Ultrasound Therapy, Cancer Nanotechnology, and Pancreatic Islet Transplantation. His work has resulted in the publication of over 62 peer-reviewed journal articles, 16 book chapters, 5 books, 5 patents pending or granted, and 24 conference proceedings/talks, of which 69 have been as a first author and 57 as a corresponding author. His publications have been cited for over 1540 times, with an h-index of 25, and i-10 index of 37. He also serves as the chief editor, a member of editorial boards and a scientific reviewer for over 128 different journals, conferences, books, grants and dissertations.

Affiliations and Expertise

Assistant Professor, BiionixTM (Bionic Materials, Implants and Interfaces) Cluster, Department of Internal Medicine, College of Medicine, Assistant Professor by courtesy, Department of Materials Science and Engineering, University of Central Florida, USA

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