Nanobiomaterials in Soft Tissue Engineering - 1st Edition - ISBN: 9780323428651, 9780323428880

Nanobiomaterials in Soft Tissue Engineering

1st Edition

Applications of Nanobiomaterials

Editors: Alexandru Grumezescu
eBook ISBN: 9780323428880
Hardcover ISBN: 9780323428651
Imprint: William Andrew
Published Date: 18th March 2016
Page Count: 528
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Description

Nanobiomaterials in Soft Tissue Engineering brings together recent developments and the latest approaches in the field of soft tissue engineering at the nanoscale, offering a new perspective on the evolution of current and future applications. Leading researchers from around the world present the latest research and share new insights.

This book covers the major conventional and unconventional fabrication methods of typical three-dimensional scaffolds used in regenerative medicine. Surface modification and spatial properties are included in an up-to-date overview, with the latest in vivo applications of engineered 3D scaffolds discussed. The book also considers the impact, advantages and future scope of the various methods.

This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians.

Key Features

  • An informative handbook for researchers, practitioners and students working in biomedical, biotechnological and engineering fields.
  • A detailed and invaluable overview of soft tissue engineering, including the most recent scientific developments.
  • Proposes novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology.

Readership

Academic: Materials science, biotechnology and applied chemistry professors, PhD, MsC, postdocs, upper level undergraduate students.

Industry: Pharmaceutics and biotechnology companies, medical researchers, biomedical engineers, advanced clinicians.

Table of Contents

  • List of contributors
  • Preface of the series
  • Preface
    • About the Series (Volumes I–XI)
    • About Volume V
  • Chapter 1. Soft tissue engineering and microbial infections: Challenges and perspectives
    • Abstract
    • 1.1 Introduction
    • 1.2 Biomaterials Used in Soft Tissue Engineering
    • 1.3 Biomaterial Microbial Colonization and Biofilm-Associated Infections
    • 1.4 Antimicrobial Polymers Used in Soft Tissue Engineering
    • 1.5 Conclusions
    • Acknowledgment
    • References
  • Chapter 2. Nanotechnology approaches for skin wound regeneration using drug-delivery systems
    • Abstract
    • 2.1 Introduction
    • 2.2 Cutaneous Wound Healing and Skin Lesions
    • 2.3 Therapeutic Agents for Wound-Healing Therapy
    • 2.4 Nanotechnology Approaches for the Release of Therapeutic Agents for Wound Healing
    • 2.5 Conclusions
    • References
  • Chapter 3. Bacterial cellulose for advanced medical materials
    • Abstract
    • List of Abbreviations
    • 3.1 Introduction
    • 3.2 Bacterial Cellulose
    • 3.3 Fermentative Changes: New Biocomposites
    • 3.4 Medical Applications of Bacterial Cellulose
    • 3.5 GTR Membranes
    • 3.6 Another Application: Drug Delivery
    • 3.7 Future Materials—Genetic Modifications
    • 3.8 Conclusions
    • References
  • Chapter 4. Applications of nanobiopolymers for soft tissue engineering
    • Abstract
    • 4.1 Introduction
    • 4.2 Nanobiopolymers for Neural Tissue Engineering
    • 4.3 Nanobiopolymers for Cardiovascular Tissue Engineering
    • 4.4 Nanobiopolymers for Cartilage and Ligament TE
    • 4.5 Nanobiopolymers for Skin TE
    • 4.6 Conclusions and Future Perspectives
    • Acknowledgments
    • References
  • Chapter 5. Machine design for multimaterial processing
    • Abstract
    • 5.1 Introduction
    • 5.2 The Role of the Scaffolds in TE: Design Features
    • 5.3 RP of 3D Scaffolds
    • 5.4 Device Design
    • 5.5 Dimensional Analysis of the Maryland Manipulator for a Given Workspace
    • 5.6 Inverse Kinematic Model of the Maryland Manipulator
    • 5.7 Jacobian Matrix Generation
    • 5.8 Dynamics Modeling with Principle of Virtual Works
    • 5.9 Results of Device Design
    • 5.10 Scaffold Fabrication
    • 5.11 Conclusions
    • References
  • Chapter 6. Advanced nanobiomaterials in tissue engineering: Synthesis, properties, and applications
    • Abstract
    • 6.1 Introduction
    • 6.2 Natural and Synthetic Biopolymers for Tissue Engineering
    • 6.3 Poly-Lactic Acid
    • 6.4 Design and Fabrication of Scaffolds
    • 6.5 Processing Methods for Nanocomposites in Tissue Engineering
    • 6.6 Conclusions
    • References
  • Chapter 7. Collagen-based nanobiomaterials: Challenges in soft tissue engineering
    • Abstract
    • 7.1 Introduction
    • 7.2 General Description and Origin
    • 7.3 Collagen Structure
    • 7.4 Collagen Types
    • 7.5 Collagen Extraction Methods
    • 7.6 Collagen Sources
    • 7.7 Biomedical Applications of Collagen in Soft Tissue Engineering
    • 7.8 Conclusions and Perspectives
    • References
  • Chapter 8. Micro/nanofiber-based scaffolds for soft tissue engineering applications: Potential and current challenges
    • Abstract
    • 8.1 Introduction
    • 8.2 Electrospinning as a Versatile Processing Technique for Scaffolding
    • 8.3 Electrospun Structures for Tissue Engineering Applications
    • 8.4 Soft Tissue Engineering Applications
    • 8.5 Concluding Remarks and Future Directions
    • Acknowledgments
    • References
  • Chapter 9. Natural polymer-based hydrogels as scaffolds for tissue engineering
    • Abstract
    • 9.1 Introduction
    • 9.2 Tissue Engineering
    • 9.3 Natural Polymers for Hydrogel Scaffolds in Tissue Engineering
    • 9.4 Hydrogel Scaffolds
    • 9.5 Classification of Hydrogels
    • 9.6 Method of Fabricating Hydrogels
    • 9.7 Scaffold Fabrication Methods
    • 9.8 Currently Applied Three-Dimensional Scaffold Fabrication Technologies
    • 9.9 Characterization of Hydrogel Scaffold
    • 9.10 In Vitro Drug Release
    • 9.11 Applications of Hydrogels
    • 9.12 Other Scaffolds
    • 9.13 Future Perspectives
    • Acknowledgments
    • References
  • Chapter 10. Bioactive nanomaterials for cartilage and muscle regeneration
    • Abstract
    • 10.1 Cartilage Tissue
    • 10.2 Muscle Tissue
    • 10.3 Conclusions
    • Acknowledgments
    • References
  • Chapter 11. Fabrication of complex biomaterial scaffolds for soft tissue engineering by electrospinning
    • Abstract
    • 11.1 Introduction
    • 11.2 Electrospinning of Fibrous Scaffolds
    • 11.3 Influence of Architecture of Microfiber Meshes on Cell Behavior
    • 11.4 Surface Modification
    • 11.5 Complex Scaffolds
    • 11.6 Limitations with Electrospinning and Future Opportunities
    • References
  • Chapter 12. Oxygen-generating nanobiomaterials for the treatment of diabetes: A tissue engineering approach
    • Abstract
    • List of Abbreviations
    • 12.1 Introduction
    • 12.2 Tissue Engineering
    • 12.3 Diabetes
    • 12.4 Therapeutic Approaches
    • 12.5 Conclusions
    • References
  • Chapter 13. Advances in the field of soft tissue engineering: From pure regenerative to integrative solutions
    • Abstract
    • 13.1 Soft Tissue Engineering
    • 13.2 Conclusions and Perspectives
    • Acknowledgments
    • References
  • Chapter 14. Tissue engineering: Use of electrospinning technique for recreating physiological functions
    • Abstract
    • List of Abbreviations
    • 14.1 Introduction
    • 14.2 Tissue Engineering
    • 14.3 Application of Tissue Engineering in Artificial Organs
    • 14.4 Challenges in Tissue Engineering
    • 14.5 The Future
    • References
  • Chapter 15. In vivo microscopic and mechanical characteristics of bioengineered and biodegradable tissue scaffolds and nanomaterials
    • Abstract
    • 15.1 Introduction
    • 15.2 Wound Healing
    • 15.3 Angiogenesis
    • 15.4 Biomaterials Used in Wound Healing
    • 15.5 Animal Models
    • 15.6 In Vivo Microscopic and Mechanical Characterization of Biomaterials
    • 15.7 Testing and Assessment of Degradation
    • 15.8 Conclusions
    • Acknowledgments
    • References
  • Index

Details

No. of pages:
528
Language:
English
Copyright:
© William Andrew 2016
Published:
Imprint:
William Andrew
eBook ISBN:
9780323428880
Hardcover ISBN:
9780323428651

About the Editor

Alexandru Grumezescu

Alexandru Grumezescu

Dr. Alexandru Mihai Grumezescu is Assistant Professor at the Department of Science and Engineering of Oxide Materials and Nanomaterials, in the Faculty of Applied Chemistry and Materials Science, with a second affiliation to the Faculty of Medical Engineering, at the Politehnica University of Bucharest in Romania. He is an experienced and oft-published researcher and editor in the field of nano and biostructures, and he is the Editor-in-Chief of three journals: Biointerface Research in Applied Chemistry, Letters and Applied NanoBioScience, Biomaterials and Tissue Engineering Bulletin, and Journal of Food Bioengineering and Nanoprocessing. He also serves as editor or guest editor for several notable journals. Dr. Grumezescu has published 150 peer-reviewed papers, 20 book chapters, 8 co-authored books and 21 edited books. He has developed two new research directions related to bio-applications of metal oxide nanoparticles: (i) functional metal oxide nanostructures to improve the delivery of antimicrobials in active form with a high efficiency against Gram-positive and Gram-negative bacteria; and (ii) smart metal oxide nanostructures, functionalized with different fatty acids, essential oils or in combination with organic polymers, to inhibit bacterial colonization of different medical or industrial surfaces. Dr Alexandru Mihai Grumezescu is also Assistant Professor at the Department of Science and Engineering of Oxide Materials and Nanomaterials, in the Faculty of Applied Chemistry and Materials Science at the Politehnica University of Bucharest in Romania. He is an experienced and oft-published researcher and editor in the field of nano- and biostructures, and he is the Editor-in-Chief of four journals: Biointerface Research in Applied Chemistry, Letters and Applied NanoBioScience, Biomaterials and Tissue Engineering Bulletin, and Journal of Food Bioengineering and Nanoprocessing. He also serves as editor or guest editor for several notable journals. Dr Grumezescu has published 160 peer-reviewed papers, 20 book chapters, 9 coauthored books, and 21 edited books. Other details are available at http://grumezescu.com/.

Affiliations and Expertise

Assistant Professor, Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science and Faculty of Medical Engineering, Politehnica University of Bucharest, Romania