Nano-Pharmacokinetics and Theranostics

Nano-Pharmacokinetics and Theranostics

Advancing Cancer Therapy

1st Edition - July 28, 2021

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  • Editors: Nanasaheb Thorat, Nitesh Kumar
  • eBook ISBN: 9780323859820
  • Paperback ISBN: 9780323850506

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Description

Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians.

Key Features

  • Includes contributions from highly qualified scientists, regulatory entities, enterprises and medical practitioners to explain the long and inherently multidisciplinary pathway of nano-pharmacokinetics
  • Describes assessment methods of nano-pharmacokinetics
  • Examines the interface between nanomedicine and pharmacokinetics to diagnose and treat cancer

Readership

Researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians. Teachers and advanced students of interdisciplinary nanomedicine courses

Table of Contents

  • Section I: Nano-Pharmacokinetics Current state of the art
    1. Introduction
    2. Nano-Pharmacokinetics (NPK): Current state of the art
    3. Engineered Nanomaterials and Pharmacokinetics

    Section II: Nano-Pharmacokinetics Clinical development
    4. Nano-Pharmacokinetics: Bio distribution and toxicology
    5. Biological systems and Nano-Pharmacokinetics
    6. Nano-Pharmacokinetics Assessment

    Section III: Nano-Pharmacokinetics and cancer
    7. Clinical significance of nanomaterials in cancer treatment
    8. Nano-Pharmacokinetics and Theranostics: Co relation
    9. Nano-Pharmacokinetics key role in cancer theranostics
    10. Nano-Pharmacokinetics key role in in vivo imaging Nano-pharmacokinetics, pharmacodynamics (PK/PD) and clinical relationship
    11. Nano-Pharmacokinetics Preclinical to Clinical Translation
    12. Current pre-clinical stage of Nano-Pharmacokinetics
    13. Advances in Clinical translation of Nano-Pharmacokinetics
    14. Future Outlook and Conclusion

Product details

  • No. of pages: 324
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: July 28, 2021
  • Imprint: Academic Press
  • eBook ISBN: 9780323859820
  • Paperback ISBN: 9780323850506

About the Editors

Nanasaheb Thorat

Dr. Nanasaheb Thorat, MSc, PhD, (Gold Medal) MRSC, is an outstanding researcher currently working as Marie-Curie Fellow at Medical Science Division, University of Oxford (UK) . Dr. Thorat has published 5 Book, ~60 peer reviewed journal articles and 15 book chapters, presented 5 Keynote Speech, 25 Invited Talks at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of wider community. He is a recipient of various prestigious fellowships including Marie Skłodowska-Curie Fellowship in Poland/Switzerland 2018, Japanese Society for the Promotion of Science Fellowship in Japan 2017, Government of Ireland IRC fellowship Ireland 2015. In addition to his current research, he has been deeply engaged in collaborative work with the many eminent scientists from Japan, USA, Germany, Korea, Ireland, India, Poland, Saudi Arabia and Australia. Dr. Thorat has received European Commission’s innovation Radar “Grand Prix of the Innovation Radar Prize 2020” for developing ground-breaking technology for breast cancer theranostics.

Affiliations and Expertise

MSc, PhD, (Gold Medal) MRSC Marie Curie Fellow, Medical Science Division, University of Oxford, UK

Nitesh Kumar

Dr. Nitesh Kumar, M Pharm, PhD is an Assistant Professor from the Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur. Dr. Kumar has published 90 peer reviewed journal articles (total citations – 995 and H-index – 19) and 2 book chapters. He delivered talks and oral presentations at several scientific conferences and received awards for his research contributions. Dr. Kumar has more than 10 years of teaching and research experience and currently guiding and co-guiding 12 PhD students on their thesis work. His research work includes biocompatibility and toxicological evaluation of various drug molecules and biomedical devices namely dialysis catridges, tooth implant and electrical stimulator for glioma treatment. His other research areas are neuroprotection, hepatoprotection and neuropharmacological studies of synthesized and herbal compounds. In addition to his scientific contributions, Dr. Kumar collaborated with several government agencies and industries in India and successfully implemented projects of high impact value with successful research outcomes as principal investigator, lead investigator and co-investigator.

Affiliations and Expertise

Assistant Professor, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur (NIPER-H), Export Promotions Industrial Park (EPIP), Industrial Area Hajipur, Bihar, India

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