Na Channels from Phyla to Function

Na Channels from Phyla to Function

1st Edition - August 29, 2016

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  • Editors: Sergei Noskov, Robert J French
  • Hardcover ISBN: 9780128053867
  • eBook ISBN: 9780128092538

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Description

Na Channels from Phyla to Function, the latest volume in the Current Topics in Membranes series, is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up-to-date presentation of the current knowledge in the field of Na Channels.

Key Features

  • Written by leading experts in the field of Na Channels
  • Contains original material, both textual and illustrative, that make it a very relevant reference
  • Presented in a very comprehensive manner
  • Both researchers in the field and general readers will find this book relevant and up-to-date with regard to its information

Readership

Scientists and researchers in biochemistry and molecular and cellular biology

Table of Contents

  • 1. On the Natural and Unnatural History of the Voltage-Gated Na+ Channel
    Edward G. Moczydlowski
    2. Biophysical Adaptations of Prokaryotic Voltage Gated Sodium Channels
    Thuy N. Vien and Paul G. DeCaen
    3. Venom Peptides from Cone Snails: Pharmacological Probes for Voltage-Gated Sodium Channels
    Brad R. Green and Baldomero M. Olivera
    4. Convergent Evolution of Tetrodotoxin-Resistant Sodium Channels in Predators and Prey
    Gabriela Toledo, Charles Hanifin, Shana Geffeney and Edmund D. Brodie III
    5. Computational Structural Pharmacology and Toxicology of Voltage-Gated Sodium Channels
    Boris S. Zhorov and Denis B. Tikhonov
    6. Understanding Sodium Channel Function and Modulation Using Atomistic Simulations of Bacterial Channel Structures
    Céline Boiteux and Toby W. Allen
    7. Voltage-Gated Sodium Channels: Mechanistic Insights from Atomistic Molecular Dynamics Simulations
    Victoria Oakes, Simone Furini and Carmen Domene
    8. Simulation Studies of Ion Permeation and Selectivity in Voltage-Gated Sodium Channels
    Christopher Ing and Régis Pomès
    9. Voltage-Gated Sodium Channels: Evolutionary History and Distinctive Sequence Features
    Marina A. Kasimova, Daniele Granata and Vincenzo Carnevale
    10. Cardiac Na Channels: Structure to Function
    Kevin R. DeMarco and Colleen E. Clancy
    11. Developmental and Regulatory Functions of Na+ Channel Non-pore-forming Subunits
    Jesse J. Winters and Lori L. Isom
    12. Lipid Regulation of Sodium Channels
    Nazzareno D’Avanzo
    13. Mechanism of Inactivation in Voltage-Gated Na+ Channels
    Vaibhavkumar S. Gawali and Hannes Todt
    14. Current-Voltage Relationship for Late Na+ Current in Adult Rat Ventricular Myocytes
    R. B. Clark and Wayne R. Giles
    15. Physiology and Pathophysiology of Sodium Channel Inactivation
    Mohammad-Reza Ghovanloo, Kelsey Aimar, Rouzbeh Ghadiry-Tavi, Alec Yu and Peter C. Ruben
    16. Cardiac Sodium Channel Mutations: Why So Many Phenotypes?
    Man Liu, Kai-Chien Yang and Samuel C. Dudley Jr.
    17. Nav Channels in Damaged Membranes
    Catherine E. Morris and Béla Joos
    18. Unusual Voltage-Gated Sodium Currents as Targets for Pain
    Cindy Barbosa and Theodore R. Cummins

Product details

  • No. of pages: 678
  • Language: English
  • Copyright: © Academic Press 2016
  • Published: August 29, 2016
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128053867
  • eBook ISBN: 9780128092538

About the Serial Volume Editors

Sergei Noskov

Prof. Sergei Noskov works at the Department of Biological Sciences, University of Calgary, Canada.

Affiliations and Expertise

Department of Biological Sciences, University of Calgary, Canada.

Robert J French

Professor Robert French works at the Department of Physiology and Pharmacology, and is a Member of the Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary,

Affiliations and Expertise

Department of Physiology & Pharmacology, University of Calgary, Canada

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