COVID-19 Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. To provide all customers with timely access to content, we are offering 50% off Science and Technology Print & eBook bundle options. Terms & conditions.
Na Channels from Phyla to Function - 1st Edition - ISBN: 9780128053867, 9780128092538

Na Channels from Phyla to Function, Volume 78

1st Edition

Serial Volume Editors: Sergei Noskov Robert J French
Hardcover ISBN: 9780128053867
eBook ISBN: 9780128092538
Imprint: Academic Press
Published Date: 29th August 2016
Page Count: 678
Sales tax will be calculated at check-out Price includes VAT/GST
Price includes VAT/GST

Institutional Subscription

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Table of Contents

1. On the Natural and Unnatural History of the Voltage-Gated Na+ Channel
Edward G. Moczydlowski
2. Biophysical Adaptations of Prokaryotic Voltage Gated Sodium Channels
Thuy N. Vien and Paul G. DeCaen
3. Venom Peptides from Cone Snails: Pharmacological Probes for Voltage-Gated Sodium Channels
Brad R. Green and Baldomero M. Olivera
4. Convergent Evolution of Tetrodotoxin-Resistant Sodium Channels in Predators and Prey
Gabriela Toledo, Charles Hanifin, Shana Geffeney and Edmund D. Brodie III
5. Computational Structural Pharmacology and Toxicology of Voltage-Gated Sodium Channels
Boris S. Zhorov and Denis B. Tikhonov
6. Understanding Sodium Channel Function and Modulation Using Atomistic Simulations of Bacterial Channel Structures
Céline Boiteux and Toby W. Allen
7. Voltage-Gated Sodium Channels: Mechanistic Insights from Atomistic Molecular Dynamics Simulations
Victoria Oakes, Simone Furini and Carmen Domene
8. Simulation Studies of Ion Permeation and Selectivity in Voltage-Gated Sodium Channels
Christopher Ing and Régis Pomès
9. Voltage-Gated Sodium Channels: Evolutionary History and Distinctive Sequence Features
Marina A. Kasimova, Daniele Granata and Vincenzo Carnevale
10. Cardiac Na Channels: Structure to Function
Kevin R. DeMarco and Colleen E. Clancy
11. Developmental and Regulatory Functions of Na+ Channel Non-pore-forming Subunits
Jesse J. Winters and Lori L. Isom
12. Lipid Regulation of Sodium Channels
Nazzareno D’Avanzo
13. Mechanism of Inactivation in Voltage-Gated Na+ Channels
Vaibhavkumar S. Gawali and Hannes Todt
14. Current-Voltage Relationship for Late Na+ Current in Adult Rat Ventricular Myocytes
R. B. Clark and Wayne R. Giles
15. Physiology and Pathophysiology of Sodium Channel Inactivation
Mohammad-Reza Ghovanloo, Kelsey Aimar, Rouzbeh Ghadiry-Tavi, Alec Yu and Peter C. Ruben
16. Cardiac Sodium Channel Mutations: Why So Many Phenotypes?
Man Liu, Kai-Chien Yang and Samuel C. Dudley Jr.
17. Nav Channels in Damaged Membranes
Catherine E. Morris and Béla Joos
18. Unusual Voltage-Gated Sodium Currents as Targets for Pain
Cindy Barbosa and Theodore R. Cummins


Na Channels from Phyla to Function, the latest volume in the Current Topics in Membranes series, is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up-to-date presentation of the current knowledge in the field of Na Channels.

Key Features

  • Written by leading experts in the field of Na Channels
  • Contains original material, both textual and illustrative, that make it a very relevant reference
  • Presented in a very comprehensive manner
  • Both researchers in the field and general readers will find this book relevant and up-to-date with regard to its information


Scientists and researchers in biochemistry and molecular and cellular biology


No. of pages:
© Academic Press 2016
29th August 2016
Academic Press
Hardcover ISBN:
eBook ISBN:

Ratings and Reviews

About the Serial Volume Editors

Sergei Noskov

Prof. Sergei Noskov works at the Department of Biological Sciences, University of Calgary, Canada.

Affiliations and Expertise

Department of Biological Sciences, University of Calgary, Canada.

Robert J French

Professor Robert French works at the Department of Physiology and Pharmacology, and is a Member of the Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary,

Affiliations and Expertise

Department of Physiology & Pharmacology, University of Calgary, Canada