Myeloid-Derived Suppressor Cells

Myeloid-Derived Suppressor Cells

1st Edition - April 1, 2023

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  • Editors: Carlos Jiménez-Cortegana, Lorenzo Galluzzi
  • Hardcover ISBN: 9780443191275

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Myeloid-Derived Suppressor Cells, Volume 375 includes comprehensive and detailed reviews on the current advances in myeloid derived suppressor cells, an immature, heterogenous cell population from the myeloid lineage that has been extensively described in the last decades due to its potent immunosuppressive activity in a variety of pathologies. Chapters in this new release include Cancer-cell-intrinsic mechanisms regulate myeloid-derived suppressor cells through cytokine networks, Role of myeloid-derived suppressor cells in head and neck cancer, Role of myeloid-derived suppressor cells in breast cancer, Role of myeloid-derived suppressor cells in endometriosis, Role of myeloid-derived suppressor cells in ovarian cancer, Role of myeloid-derived suppressor cells in sarcoma, and more.

Key Features

  • Contains chapters led by selected experts on the topic of myeloid-derived suppressor cells
  • Includes comprehensive and detailed knowledge on myeloid-derived suppressor cells in different diseases
  • Offers a wide range of perspectives on specific diseases


researchers who are interested in the MDSC-mediated immunosuppression in different pathologies

Table of Contents

  • Preface

    Lorenzo Galluzzi and Carlos Jiménez

    1. Cancer-cell-intrinsic mechanisms regulate MDSCs through cytokine networks

    Yuting Zhang, Sean Murphy and Xin Lu

    2. Myeloid-derived suppressor cells in head and neck squamous cell carcinoma

    Jing-Yu He, Fang-Yi Huo, Hong-Chao Tang, Bing Liu and Lin-Lin Bu

    3. Knowing the myeloid-derived suppressor cells (MDSC): Another enemy of sarcomas patients

    Daniel J. García-Domínguez, Víctor Sánchez-Margalet, Luis de la Cruz-Merino and Lourdes Hontecillas-Prieto

    4. Role of MDSCs during Trypanosoma cruzi infection

    Borgna Eliana, Prochetto Estefanía, Gamba Juan Cruz, Marcipar Iván and Cabrera Gabriel

    5. Emerging avenues linking myeloid-derived suppressor cells to periodontal disease

    Ana Gabriela Leija Montoya, Javier González Ramírez, Idanya Serafín Higuera,
    Jorge Sandoval Basilio, Mario Isiordia Espinoza and Nicolás Serafín Higuera

    6. Myeloid-derived suppressor cells: A new emerging player in endometriosis

    Tao Zhang, Ying He, Gene Chi Wai Man, Yang Ding, Chi Chiu Wang and Jacqueline Pui Wah Chung

Product details

  • No. of pages: 278
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: April 1, 2023
  • Imprint: Academic Press
  • Hardcover ISBN: 9780443191275

About the Serial Volume Editors

Carlos Jiménez-Cortegana

Carlos Jiménez-Cortegana
Carlos Jiménez-Cortegana obtained the degree in Chemistry at University of Seville (Spain) in 2014. In July 2020 he got the PhD in Clinical Research at the same University, belonging to the group headed by Dr. Luis de la Cruz-Merino and Dr. Víctor Sánchez-Margalet. Currently, Carlos is a Postdoctoral Researcher at the Department of Radiation Oncology, Weill Cornell Medical College (New York, USA), in the research group headed by Dr. Lorenzo Galluzzi. From 2021, Carlos has published more than 15 articles in recognized, international journals, some of them in high-impact factor journals, mainly focused on the immunosuppressive role of myeloid-derived suppressor cells in a variety of diseases, including breast cancer, diffuse large B-cell lymphoma, and COVID-19.

Affiliations and Expertise

Radiation Oncology, Weill Cornell Medical College, New York, NY, USA; Department of Medical Biochemistry, Molecular Biology and Immunology, Faculty of Medicine, University of Seville, Seville, Spain

Lorenzo Galluzzi

Lorenzo Galluzzi
Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology. Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.

Affiliations and Expertise

Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA

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