Muscle Biopsy: A Practical Approach - 4th Edition - ISBN: 9780702043406, 9780702050305

Muscle Biopsy: A Practical Approach

4th Edition

Expert Consult; Online and Print

Authors: Victor Dubowitz Victor Dubowitz Caroline Sewry Anders Oldfors
Hardcover ISBN: 9780702043406
eBook ISBN: 9780702050305
Imprint: Saunders Ltd.
Published Date: 1st April 2013
Page Count: 592

Description

2014 BMA Medical Book Awards Highly Commended in Pathology category!

Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, internationally renowned figure in the field of muscle disease, this medical reference book takes an integrated approach to diagnosis and assessment of muscle biopsies that includes clinical, genetic, biochemical, and pathological features. It's the comprehensive, up-to-date coverage you need to evaluate muscle disorders with confidence

"Overall, this is a well written and comprehensive textbook of muscle pathology that will be of invaluable assistance to laboratories reporting muscle pathology"  Reviewed by The Bulletin of The Royal College of Pathologists, Jan 2015

Key Features

  • Bridge the gap between clinical syndromes/disorders and their underlying pathologies with the guidance of muscle disease expert, Dr. Victor Dubowitz, who skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment.
  • Understand and apply expert techniques for obtaining a muscle biopsy, and familiarize yourself with the histochemical, histological, electron microscopical, and molecular appearance of normal muscle and the pathology of individual muscle disease.
  • Read the entire contents and download all of the images online at Expert Consult.

Table of Contents

Section 1 The Biopsy: Normal and Diseased Muscle

1. The procedure of muscle biopsy

2. Histological and histochemical stains and reactions

3. Normal muscle

4. Definition of pathological changes seen in muscle biopsies

5. Ultrastructural changes in diseased muscle

6. Immunohistochemistry

7. How to read a biopsy


Section 2 Pathological Muscle: Individual Diseases

8. Classification of neuromuscular disorders

9. Neurogenic disorders

10. Muscular dystrophies and allied disorders I: Duchenne and Becker muscular dystrophy

11. Muscular dystrophies and allied disorders II: limb-girdle muscular dystrophies

12. Muscular dystrophies and allied disorders III: congenital muscular dystrophies

13. Muscular dystrophies and allied disorders IV: Emeryƒ{Driefuss muscular dystrophies and Bethlem myopathy

14. Muscular dystrophies and allied disorders V: facioscapulohumeral dystrophy, myotonic dystrophy, oculopharyngeal muscular dystrophy

15. Congenital myopathies

16. Myofibrillar myopathies

17. Metabolic myopathies I: glycogenoses

18. Metabolic myopathies II: lipid related disorders and mitochondrial myopathies

19. Endocrine disorders

20. Ion channel disorders

21. Myasthenic syndromes

22. Inflammatory myopathies

23. Toxic and drug-induced myopathies
Russell Lane, Charing Cross Hospital


Appendix 1. Glossary of commonly used terms


References


Index

Details

No. of pages:
592
Language:
English
Copyright:
© Saunders Ltd. 2013
Published:
Imprint:
Saunders Ltd.
eBook ISBN:
9780702050305
eBook ISBN:
9780702057656
Hardcover ISBN:
9780702043406

About the Author

Victor Dubowitz

Affiliations and Expertise

Emeritus Professor of Paediatrics Dubowitz Neuromuscular Centre Faculty of Medicine Imperial College London Hammersmith Campus London

Victor Dubowitz

Affiliations and Expertise

Emeritus Professor of Paediatrics Dubowitz Neuromuscular Centre Faculty of Medicine Imperial College London Hammersmith Campus London

Caroline Sewry

Affiliations and Expertise

Professor of Muscle Pathology, Dubowitz Neuromuscular Centre, Imperial College Faculty of Medicine, Hammersmith Hospital, London, UK; Centre for Inherited Neuromuscular Disorders, Department of Histopathology, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, UK

Anders Oldfors

Affiliations and Expertise

Professor and Director Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden

Reviews

"The third edition of this book...has surpassed my expectations. The quality of the book overall is excellent, from the production and layout to the illustrations, diagrams and index. The range of muscle diseases included spans both adults and children, with an integrated approach to diagnosis including clinical, genetic, biochemical and pathological features. Overall, this book has been a highlight of the past year for me. It deserves to do very well indeed and will be of immense value beyond its target readership." BMA Awards 2007

"The book is aimed at diagnostic pathologists and the authors have made a sensible and valid attempt to harmonise classical nomenclature with the new advances in genetics that threaten to overturn previous attempts at classifying muscle disease.

Overall, this is a well written and comprehensive textbook of muscle pathology that will be of invaluable assistance to laboratories reporting muscle pathology."

Reviewed by: Dr Ian S Scott Consultant Neuropathologist Queen’s Medical Centre Nottingham  Date: Jan 2015