Muscle Biology

Muscle Biology

The Life History of a Muscle

1st Edition - November 26, 2021

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  • Author: Bruce Carlson
  • Paperback ISBN: 9780128202784
  • eBook ISBN: 9780128202791

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Muscle Biology: The Life History of a Muscle looks at the story of a muscle from its embryonic beginnings, through its growth and ability to adapt to changing functional circumstances during adult life, to its eventual decline in both structure and function as old age progresses. Injury occurs to muscle during normal activity, after trauma, and during the source of certain diseases. Chapters on both muscle regeneration and muscle diseases emphasize the possibilities and limitsations of the healing capacity of muscle fibers. Muscle Biology begins with a brief review about the structure and function of a normal mature muscle and then proceeds to follow the developmental history of a muscle from the embryo to old age in a manner that gives the reader a perspective about not only developmental controls but also how at any stage of development a muscle is able to adapt to its functional environment. The book discusses both normal and abnormal changes in the muscle, the mechanisms behind those changes and how to mitigate deleterious changes from disease, 'normal' aging, and disuse/lack of physical activity. This is a must-have reference for students, researchers and practitioners in need of a comprehensive overview of muscle biology.

Key Features

  • Provides an overview of muscle biology over the course of one’s entire lifespan
  • Explains the important elements of each aspect of muscle biology without drowning the reader in excessive detail
  • Contains over 300 illustrations and includes chapter summaries


Upper undergraduate, graduates, postdocs, professors and researchers studying biology, anatomy, physiology, developmental biology, pathophysiology, aging/gerontology, kinesiology/movement science and those across the life sciences interested in muscles/muscle biology as well as practitioners in physical therapy and occupational therapy

Table of Contents

  • Preface


    1.  Mature Skeletal Muscle - An Overview

    2. Embryonic Origins of Skeletal Muscle

    3. Normal Muscle Growth

    4. Muscle Adaptation to Increased Use

    5. Muscle Adaptation to Decreased Use

    6. Muscle Injury and Regeneration

    7. Muscle Disorders

    8. The Aging of Muscle



Product details

  • No. of pages: 212
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: November 26, 2021
  • Imprint: Academic Press
  • Paperback ISBN: 9780128202784
  • eBook ISBN: 9780128202791

About the Author

Bruce Carlson

Bruce M. Carlson, MD, PhD, is Professor Emeritus of Anatomy in the Department of Cell and Developmental Biology in the University of Michigan Medical School in Ann Arbor. He served as chair of that department from 1998-2000. He is also Research Professor Emeritus in the school’s Institute of Gerontology, of which he was the director from 2000 to 2003. Professor Carlson writes the majority of the book himself but he has suggested that he may bring in one or two contributors this time round to cover areas that he is not as up to date on as he once was. We have spoken about bringing in a co-author and he is open for this to happen for the 7th edition when he has had time to find someone suitable.

Affiliations and Expertise

Professor, Department of Cell and Developmental Biology; Director, Institute of Gerontology, University of Michigan, Ann Arbor, MI

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