Muscle Biology

Muscle Biology

The Life History of a Muscle

1st Edition - November 28, 2021

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  • Author: Bruce Carlson
  • Paperback ISBN: 9780128202784
  • eBook ISBN: 9780128202791

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Muscle Biology: The Life History of a Muscle looks at the story of a muscle from its embryonic beginnings, through its growth and ability to adapt to changing functional circumstances during adult life, to its eventual decline in both structure and function as old age progresses. Injury occurs to muscle during normal activity, after trauma, and during the source of certain diseases. Chapters on both muscle regeneration and muscle diseases emphasize the possibilities and limitsations of the healing capacity of muscle fibers. Muscle Biology begins with a brief review about the structure and function of a normal mature muscle and then proceeds to follow the developmental history of a muscle from the embryo to old age in a manner that gives the reader a perspective about not only developmental controls but also how at any stage of development a muscle is able to adapt to its functional environment. The book discusses both normal and abnormal changes in the muscle, the mechanisms behind those changes and how to mitigate deleterious changes from disease, 'normal' aging, and disuse/lack of physical activity. This is a must-have reference for students, researchers and practitioners in need of a comprehensive overview of muscle biology.

Key Features

  • Provides an overview of muscle biology over the course of one’s entire lifespan
  • Explains the important elements of each aspect of muscle biology without drowning the reader in excessive detail
  • Contains over 300 illustrations and includes chapter summaries


Upper undergraduate, graduates, postdocs, professors and researchers studying biology, anatomy, physiology, developmental biology, pathophysiology, aging/gerontology, kinesiology/movement science and those across the life sciences interested in muscles/muscle biology as well as practitioners in physical therapy and occupational therapy

Table of Contents

  • Preface


    1.  Mature Skeletal Muscle - An Overview

    2. Embryonic Origins of Skeletal Muscle

    3. Normal Muscle Growth

    4. Muscle Adaptation to Increased Use

    5. Muscle Adaptation to Decreased Use

    6. Muscle Injury and Regeneration

    7. Muscle Disorders

    8. The Aging of Muscle



Product details

  • No. of pages: 212
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: November 28, 2021
  • Imprint: Academic Press
  • Paperback ISBN: 9780128202784
  • eBook ISBN: 9780128202791

About the Author

Bruce Carlson

Dr. Carlson serves as Professor Emeritus of Anatomy in the Department of Cell and Developmental Biology in the University of Michigan Medical School in Ann Arbor. Dr. Carlson is the author of more than fifteen book publications including several books published by Elsevier (Human Embryology and Developmental Biology 1-5/e, Principles of Regenerative Biology, repurposed embryology and physiology texts for Elsevier’s digital Reference Module in Biomedical Sciences in 2014). Dr. Carlson has served as president of the American Association of Anatomists, and president of the Association of Anatomy, Cell Biology, and Neurobiology Chairpersons. Additional honors include the AAAS Newcomb-Cleveland Prize, membership in the Russian Academy of Natural Sciences, and the Henry Gray Award of the American Association of Anatomists. An accomplished teacher, Dr. Carlson has received both the Elizabeth Crosby Teaching Award and the Kaiser-Permanente Teaching Award from the University of Michigan Medical School.

Affiliations and Expertise

Professor Emeritus of Anatomy, Department of Cell and Developmental Biology, University of Michigan Medical School, USA

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