List of contributors. Preface. A Memorial for David de Wied.
1. Concepts of Stress.
1.1 Stress: An historical perspective S. Levine.
1.2 The Neuropsychology of stress T. Steckler.
1.3 An introduction to the HPA axis A.J. Fulford and M.S. Harbuz
1.4 Hormones of the pituitary M. Páez-Pereda and Günter K. Stalla.
1.5 Molecular biology of the HPA axis K.-B. Abel and J.A. Majzoub.
1.6 The hypothalamic-pituitary-adrenal axis as a dynamically organized system: lessons from exercising mice J.M.H.M. Reul and S.K. Droste.
2. Hypothalamic Hormones Involved in Stress Responsivitity.
2.1 Novel CRH family peptides and their receptors: an evolutionary analysis S.Y.T. Hsu.
2.2 Regulation of CRF activity on the molecular level P.H. Roseboom, N.H. Kalin, T. Steckler and F.M. Dautzenberg.
2.3 Behavioral consequences of altered corticotropin-releasing factor activation in brain: a functionalist view of affective neuroscience S.C. Heinrichs.
2.4 The roles of urocortins 1, 2 and 3 in the brain E.P. Zorrilla and G.F. Koob.
2.5 Vasopressin and oxytocin A.J. Douglas.
2.6 The role of vasopressin in behaviours associated with aversive stimuli K.C. Chambers and U.L. Hayes.
3. Stress and the HPA Axis.
3.1 Corticosteroid receptors and HPA axis regulation E.R. De Kloet, M. Schmidt and O.C. Meijer.
3.2 Glucocorticoid effects on gene expression T. Kino and G.P. Chrousos.
3.3 The role of 11ß-hydroxysteroid dehydrogenases in the regulation of corticosteroid activity in the brain J.R. Seckl, J.L.W. Yau and M.C. Holmes.