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This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference.
Broad-based overview of mouse development from fundamental to specialist levels
Extensive coverage of a wide range of developmental mutations of the mouse
Excellent benchmark illustrations of brain, craniofacial, gut and heart development
In-depth experiment-based assessment of concepts in mammalian development
Focus on models of specific relevance to human development
Comprehensive reference to key literature and electronic databases related to mouse development
*High-quality full-color production
Developmental biologists, cell biologists, and molecular biologists.
Establishment of Body Pattern
Fertilization and Activation of the Embryonic Genome
Asymmetry and Pre-Pattern in Mammalian Development
Anterior Posterior Patterning of the Mouse Body Axis at Gastrulation
Patterning, Regionalization and Cell Differentiation in the Forebrain
Establishment of Anterior-Posterior and Dorsal-Ventral Pattern in the Early Central Nervous System
Somitogenesis: Segmentation of the Paraxial Mesoderm and the Delineation of Tissue Compartments
II. Lineage Specification and Differentiation
Development of the Vertebrate Hematopoetic System
Vasculogenesis and Angiogenesis
Stem Cells of the Nervous System
Cellular and Molecular Mechanisms Regulating Skeletal Muscle Development
Chondrogenesis and Skeletogenesis
Development of the Endoderm and its Tissue Derivatives
Heart Development: Induction, Myogenesis and Patterning
Sex Determination and Differentiation
The Development of the Excretory System
Pituitary Gland Development
Sensory Organs: Eye
Development of the Mouse Inner Ear
- No. of pages:
- © Academic Press 2002
- 1st March 2001
- Academic Press
- eBook ISBN:
- Hardcover ISBN:
Samuel Lunenfeld Research Institute, Toronto, Canada
@qu:"...two of the most respected mouse developmental biologists have produced an exceptional book. Right from the outset, it highlights the incredible explosion in our knowledge and understanding of mammalian development over the past decade...will sit very comfortably upon any bookshelf."
@source:—Paul Trainor, Stowers Institute for Medical Research for NATURE CELL BIOLOGY (September 2002)
@qu:"...an excellent resource for scientists interested in any of the selected topics covered by one of the authors."
@source:—DOODY'S NOTES (2002)
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