Motor Neuron Disorders

1st Edition

Blue Books of Practical Neurology Series

Authors: Pamela Shaw Michael Strong
Hardcover ISBN: 9780750674423
eBook ISBN: 9780702038877
Imprint: Butterworth-Heinemann
Published Date: 1st August 2003
Page Count: 592

Description

Clinical and scientific text on the current knowledge about motor neuron disorders, most especially amyotrophic lateral sclerosis.

Key Features

  • Reader will have available most up-to-date information from the leading experts in this subspecialty who have been doing the research and are deeply involved in clinical practice.
  • Thorough coverage of a very difficult-to-diagnose and hard-to-manage group of disorders.
  • Readers will be able to manage their patients' care more accurately and will be able to distinguish not only among the motor neuron disorders themselves but also be able to determine whether the disease is another neuromuscular disorder entirely.

Table of Contents


Key Principles in the Clinical Diagnosis, Pathology & Investigation of Motor Neuron Disorders
1
Clinical Principles in the Differential Diagnosis of Motor Neuron Disorders
2
Pathology of Motor Neuron Disorders
3
Neurophysiological Investigation of Motor Neuron Disorders
4
Neuroimaging in Notor Neuron Disorders

Motor Neuron Disease/Amyotrophic Lateral Sclerosis
5
Clinical Aspects of ALS/MND
6
Cognitive Impairment in the Motor Neuron Disease
7
Epidemiology of ALS/MND
8
Genetic Aspects of ALS/MND
9
Cellular Bioligical Effects of SODI Mutations
10
Excitotoxicity & Oxidative Stress in the Pathogenesis of ALS/MND
11
Mitochondrial Dysfunction in Amyotrophic Lateral Sclerosis (ALS)
12
Cyto skeletal Abnormatlities in ALS/MND
13
The role of Microglia in Amyotrophic Lateral Sclerosis
14
Cell Death Pathways in Amyotrophic Lateral Sclerosis
15
Factors Underlying the Selective Vulnerability of Motor Neurons to Neurodegeneration

Other Motor Neuron Disorders
16
Spinal Muscular Atrophy
17
Kennedy's Disease
18
Hereditary Spastic Paraparesis

Therapeutics of Motor Neuron Disorders
19
Quality of Life & Psychosocial Aspects of Care of Patients with ALS
20
Sympton Control in ALS/MND
21
Disease Modifying Therapies in Motor Neuron Disorders: The Present Position and Petential Future Developments
FM

Index




Details

No. of pages:
592
Language:
English
Copyright:
© Butterworth-Heinemann 2003
Published:
Imprint:
Butterworth-Heinemann
eBook ISBN:
9780702038877
Hardcover ISBN:
9780750674423

About the Author

Pamela Shaw

Affiliations and Expertise

Professor of Neurology, Academic Neurology Unit, Division of Genomic Medicine, University of Sheffield, Sheffield, UK

Michael Strong

Affiliations and Expertise

Professor and Chief, Division of Neurology, University of Western Ontario Faculty of Medicine and Dentistry, London, Ontario, Canada