Morphological Mouse Phenotyping
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Morphological Mouse Phenotyping

Anatomy, Histology and Imaging

1st Edition - January 26, 2017

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  • Authors: Jose Ruberte, Ana Carretero, Marc Navarro
  • Hardcover ISBN: 9780128129722
  • eBook ISBN: 9780128128770

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Description

Morphological Mouse Phenotyping: Anatomy, Histology and Imaging is an atlas of explanatory diagrams and text that guides the reader through normal mouse anatomy, histology, and imaging. The book is targeted for mouse researchers and veterinarian and human pathologists, and presents a complete, integrative description of normal mouse morphology. Disease animal models are fundamental in research to improve human health. The success of using genetically engineered mice to evaluate molecular disease hypotheses has encouraged the development of massive global projects, making the mouse the most used animal disease model. Laboratory mouse populations are straining the housing capacity of pharmaceutical and biotechnology companies, as well as public research institutions. However, the scientific community lacks sufficient expertise in morphological phenotyping to effectively characterize and validate these animal models. The mouse displays fundamental morphological similarities to humans; however, a mouse is not a man.

Key Features

  • Features more than 2,200 original images showing the anatomy, histology, and cellular structure of mouse organs
  • Includes images specifically produced for this book in the Mouse Imaging Platform (Center for Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona)
  • Offers an integrative vision of mouse morphology using correlative X-ray, computed tomography, magnetic resonance, and ultrasound images
  • Employs classical anatomical techniques such as conventional dissection, skeletal preparations, vascular injections, and histological, immunohistochemical, and electron microscopy techniques to characterize mouse morphology

Readership

Scientists working with mice; laboratory animal vets

Table of Contents

  • 1: Introduction
    Origin of the Laboratory Mouse
    Anatomical Nomenclature

    2: Osteology
    Bones of the Skull and Mandible
    Vertebral Column and Thorax
    Bones of the Thoracic Limbs
    Bones of the Pelvic Limbs

    3: Arthrology
    Joints without Articular Cavity
    Joints with Articular Cavity

    4: Myology
    Form and Structure of Muscles
    The Skeletal Muscle Fiber
    Comparative Anatomy of Mouse Musculature

    5: Digestive tract
    Oral Cavity
    Pharynx and Esophagus
    Stomach
    Intestine
    Liver

    6: Respiratory apparatus
    Nasal Cavity
    Larynx
    Trachea
    Lungs

    7: Urinary organs
    Kidneys
    Ureter
    Urinary Bladder
    Urethra

    8: Male genital organs
    Testicles and Epididymis
    Accessory Genital Glands
    Penis

    9: Female genital organs
    Ovaries
    Uterine Tubes
    Uterus
    Vagina
    Vulva and Clitoris

    10: Anatomy of development
    Ontogenic Development
    Placenta

    11: Circulatory System
    Heart
    Arteries
    Veins
    Lymphatic System
    Blood and Lymph

    12: The endocrine glands
    Pancreas
    Adrenal Gland
    Thyroid Glands
    Parathyroid Gland
    Hypophysis

    13: Nervous System
    Central Nervous System
    Peripheral Nervous System

    14: Eye and related structures
    Eyelids and Lacrimal System
    Eyeball
    Orbit

    15: Vestibulocochlear organ
    External Ear
    Middle Ear
    Internal Ear

    16: Common integument
    Skin
    Modified Skin Structures

Product details

  • No. of pages: 600
  • Language: English
  • Copyright: © Academic Press 2017
  • Published: January 26, 2017
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128129722
  • eBook ISBN: 9780128128770

About the Authors

Jose Ruberte

Jesus Ruberte is Head of the Mouse Imaging Platform in the Center for Animal Biotechnology and Gene Therapy, Department of Animal Health and Anatomy, Veterinary School, Universitat Autonoma de Barcelona, Spain.

Affiliations and Expertise

Head of the Mouse Imaging Platform, Center for Animal Biotechnology and Gene Therapy, Department of Animal Health and Anatomy, Veterinary School, Universitat Autonoma de Barcelona, Spain

Ana Carretero

Ana Carretero works with the Mouse Imaging Platform in the Center for Animal Biotechnology and Gene Therapy, Department of Animal Health and Anatomy, Veterinary School, Universitat Autònoma de Barcelona, Spain.

Affiliations and Expertise

Mouse Imaging Platform, Center for Animal Biotechnology and Gene Therapy, Department of Animal Health and Anatomy, Veterinary School, Universitat Autònoma de Barcelona, Spain

Marc Navarro

Affiliations and Expertise

Mouse Imaging Platform, Center for Animal Biotechnology and Gene Therapy, Department of Animal Health and Anatomy, Universitat Autonoma de Barcelona, Spain

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