Monoclonal Antibodies against Bacteria

Monoclonal Antibodies against Bacteria

1st Edition - August 22, 1985

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  • Editor: Alberto Macario
  • eBook ISBN: 9780323154420

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Description

Monoclonal Antibodies against Bacteria, Volume I explores the generation, characterization, and utilization of monoclonal antibodies against bacteria and on other monoclonal products relevant to antibacterial immune responses. Organized into 12 chapters, this book begins with a discussion on monoclonal antibodies against bacteria, encompassing its scope, research, and directions. It shows that the coordinated use of antisera and panels of monoclonal antibodies is proving useful for classification as a diagnostic tool with prognostic implications in the case of pathogens, or as a preliminary step in taxonomy. Also, monoclonal antibodies hold great potential as instruments in working with bacteria for industrial or biotechnological purposes, including genetic engineering. This book also elucidates the use of monoclonal antibodies of predefined molecular specificity for tracing molecular ""signatures"" left by a given strain in other microorganisms, subcellular structures, and materials from ecologic niches. The possibility of antibacterial and antitoxin therapies with monoclonal antibodies is also addressed. This treatise will be a valuable reference work to anyone working with monoclonal antibodies or getting ready to prepare them against the strain(s) (or bacterial structures) of his/her interest.

Table of Contents


  • Contributors

    Preface

    Introduction: Monoclonal Antibodies against Bacteria for Medicine, Dentistry, Veterinary Sciences, Biotechnology, and Industry—An Overview

    Contents of Volume II

    1 Monoclonal Antibodies against Gonococcal Pili: Uses in the Analysis of Gonococcal Immunochemistry and Virulence

    I. Introduction

    II. Background

    III. Results and Discussion

    IV. Conclusions

    V. Prospects for the Future

    VI. Summary

    References

    2 Monoclonal Antibodies against Group B Streptococcus

    I. Introduction

    II. Background

    III. Methods and Results

    IV. Conclusions

    V. Summary

    References

    3 Studies with Monoclonal Antibodies to Mycobacteria

    I. Introduction

    II. Results and Discussion

    III. Conclusions and Prospects for the Future

    IV. Summary

    References

    4 Monoclonal Antibodies to Characterize the Antigenic Heterogeneity of Bacteroides intermedius

    I. Introduction

    II. Background

    III. Results and Discussion

    IV. Conclusions

    V. Prospects for the Future

    VI. Summary

    References

    5 Monoclonal Antibodies against Legionella pneumophila Serogroup 1 Antigens: Characterization and Their Potential Applications

    I. Introduction

    II. Background

    III. Results and Discussion

    IV. Conclusions

    V. Prospects for the Future

    VI. Summary

    References

    6 Monoclonal Antibodies Specific for the O-Antigen of Shigella flexneri and Shigella sonnei: Immunochemical Characterization and Clinical Usefulness

    I. Introduction

    II. Background

    III. Results and Discussion

    IV. Conclusions and Prospects for the Future

    V. Summary

    References

    7 Monoclonal Antibodies against Group- and Type-Specific Antigens of Vibrio cholerae O:1

    I. Introduction

    II. Background

    III. Results and Discussion

    IV. Conclusions

    V. Prospects for the Future

    VI. Summary

    References

    8 Monoclonal Antibodies against Tetanus Toxin and Tetanus Toxoid

    I. Introduction

    II. Background

    III. Methods for Generation of Monoclonal Antibodies

    IV. Results and Discussion

    V. Prospects for the Future

    VI. Summary

    References

    9 Human Monoclonal Antibodies for Prophylaxis and Therapy of Bacterial Infections

    I. Introduction

    II. Background

    III. Results and Discussion

    IV. Conclusions and Future Prospects

    V. Summary

    References

    10 Monoclonal T Cells and T-Cell Hybridomas with Antibacterial Activity

    I. Introduction

    II. Background

    III. Results and Discussion

    IV. Conclusions and Prospects for the Future

    V. Summary

    References

    11 A Preview of the Uses of Monoclonal Antibodies against Methanogens in Fermentation Biotechnology: Significance for Public Health

    I. Introduction

    II. Background

    III. Results and Discussion

    IV. Conclusions

    V. Prospects for the Future

    VI. Summary

    References

    12 An International Hybridoma Data Bank: Aims, Structure, Function

    I. Introduction

    II. Background of Sponsoring Organizations

    III. Operations Framework

    IV. System Design

    V. Funding and Support

    VI. Prospects for the Future

    VII. Conclusions

    VIII. Summary

    References

    Index






Product details

  • No. of pages: 358
  • Language: English
  • Copyright: © Academic Press 1985
  • Published: August 22, 1985
  • Imprint: Academic Press
  • eBook ISBN: 9780323154420

About the Editor

Alberto Macario

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