Molecular Photofitting

1st Edition

Predicting Ancestry and Phenotype Using DNA

Authors: Tony Frudakis, Ph.D.
Hardcover ISBN: 9780120884926
eBook ISBN: 9780080551371
Imprint: Academic Press
Published Date: 7th September 2007
Page Count: 712
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Description

In the field of forensics, there is a critical need for genetic tests that can function in a predictive or inferential sense, before suspects have been identified, and/or for crimes for which DNA evidence exists but eye-witnesses do not. Molecular Photofitting fills this need by describing the process of generating a physical description of an individual from the analysis of his or her DNA. The molecular photofitting process has been used to assist with the identification of remains and to guide criminal investigations toward certain individuals within the sphere of prior suspects.

Molecular Photofitting provides an accessible roadmap for both the forensic scientist hoping to make use of the new tests becoming available, and for the human genetic researcher working to discover the panels of markers that comprise these tests. By implementing population structure as a practical forensics and clinical genomics tool, Molecular Photofitting serves to redefine the way science and history look at ancestry and genetics, and shows how these tools can be used to maximize the efficacy of our criminal justice system.

Key Features

  • Explains how physical descriptions of individuals can be generated using only their DNA
  • Contains case studies that show how this new forensic technology is used in practical application
  • Includes over 100 diagrams, tables, and photos to illustrate and outline complex concepts

Readership

Geneticists, biologists, DNA researchers, forensic and physical anthropologists, practicing forensic scientists, crime laboratory personnel, crime scene personnel, Forensic consultants (generalists). Forensic professionals at the FBI, NIST, and other relevant government organizations.

Table of Contents

Chapter 1. Forensic DNA Analysis: from Modest Beginnings to Molecular Photofitting, Genics, Genetics, Genomics and the Pertinent Population Genetics Principles
Chapter 2. Ancestry and Admixture
Chapter 3. Biogeographical Ancestry Admixture Estimation - Theoretical Considerations
Chapter 4. Biogeographical Ancestry Admixture Estimation - Practicality and Application Chapter 5. Characterizing Admixture Panels Chapter 6. Apportionment of Autosomal Diversity with Continental Markers Chapter 7. Apportionment of Autosomal Diversity with Sub-Continental Markers
Chapter 8. Indirect Methods for Phenotype Inference Chapter 9. Direct Method of Phenotype Inference
Chapter 10. The First Case Studies of Molecular Photofitting
Chapter 11. The Politics and Ethics of Admixture Analysis and Molecular Photofitting

Details

No. of pages:
712
Language:
English
Copyright:
© Academic Press 2008
Published:
Imprint:
Academic Press
eBook ISBN:
9780080551371
Hardcover ISBN:
9780120884926

About the Author

Tony Frudakis, Ph.D.

Affiliations and Expertise

Chief Scientific Officer, DNAprint genomics, Inc.

Reviews

In the field of forensics, there is a critical need for genetic tests that can function in a predictive or inferential sense, before suspects have been identified, and/or for crimes for which DNA evidence exists but eye-witnesses do not. Molecular Photofitting fills this need by describing the process of generating a physical description of an individual from the analysis of his or her DNA. The molecular photofitting process has been used to assist with the identification of remains and to guide criminal investigations toward certain individuals within the sphere of prior suspects. Molecular Photofitting provides an accessible roadmap for both the forensic scientist hoping to make use of the new tests becoming available, and for the human genetic researcher working to discover the panels of markers that comprise these tests. By implementing population structure as a practical forensics and clinical genomics tool, Molecular Photofitting serves to redefine the way science and history look at ancestry and genetics, and shows how these tools can be used to maximize the efficacy of our criminal justice system.