Molecular Pharmacology V2

Molecular Pharmacology V2

The Model of Action of Biology Active Compounds

1st Edition - January 1, 1964

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  • Editor: E.J. Ariens
  • eBook ISBN: 9780323157391

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Description

Molecular Pharmacology: The Mode of Action of Biologically Active Compound, Volume II presents the mode of action of bioactive compounds on a molecular level, which concerns a wide variety of pharmacodynamic agents. This book discusses in detail the actions of odorants, the chemotherapeutics used in the fight against cancer, as well as the interactions of substrates and enzymes. Comprised of three parts, this volume starts with an overview of the mode of action of odorants and explores the anatomical and histochemical location of the receptors. This text then explains the molecular processes that are involved olfaction. Other chapters consider the different types of chemotherapeutics used against cancer, such as the antimetabolites and radiomimetics. The final chapter deals with the structure of chemical groups that constitute the receptors and the active sites on the enzymes. This book is a valuable resource for pharmacologists and clinical researchers interested in the study of bioactive compounds.

Table of Contents


  • List of Contributors

    Preface

    Contents of Volume I

    Part II A Molecular Approach to Olfaction

    I. Introduction

    II. The Carrier

    III. Material Contact or Radiation?

    IV. The Structure of the Receptor Organ

    V. Concentration of the Stimulant

    VI. Electrophysiological Methods

    VII. The Molecular Structure of the Stimulant

    VIII. Other Approaches

    IX. Related Subjects

    X. Conclusions

    References

    Part III The Molecular Basis of Cancer Chemotherapy

    I. Introduction

    II. How is Cytotoxicity Brought About?

    III. Chemotherapeutic Targets

    IV. Selective Toxicity

    V. Biological Alkylating Agents; Attempts at Improvement of Selective Toxicity

    VI. Drug Resistance

    References

    Part IV Receptor Theory in Enzymology

    Introduction

    I. Mechanism of Enzyme Action

    II. Substrate Inhibition

    III. Noncompetitive Interaction

    IV. Competitive Interaction

    V. The Receptors

    Conclusion

    References

    Author Index

    Subject Index

Product details

  • No. of pages: 292
  • Language: English
  • Copyright: © Academic Press 1964
  • Published: January 1, 1964
  • Imprint: Academic Press
  • eBook ISBN: 9780323157391

About the Editor

E.J. Ariens

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