Molecular Pathology of Pituitary Adenomas

Molecular Pathology of Pituitary Adenomas

1st Edition - October 31, 2011

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  • Authors: Cristiana Tanase, Irina Ogrezeanu, Corin Badiu
  • eBook ISBN: 9780124158528

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The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research. This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies.

Key Features

  • Facilitates the understanding of the processes involved and how they are translated into therapy
  • Illustrations are used to explain the complex mechanisms involved


Pathologists, clinical endocrinologists, neurosurgeons, basic scientists

Table of Contents

  • 1. Pituitary tumor classification: functionality, invasiveness, aggressiveness

    Irina Ogrezeanu, Corin Badiu, Cristiana Tanase, Alina Neagoe

    2. Immunohistochemistry and electron microscopy as evaluation criteria in tumour classification in the deciphering of pituitary adenomas

    Corin Badiu, Irina Ogrezeanu, Cristiana Tanase

    3. Proliferation

    Cristiana Tanase and Radu Albulescu

    4. Angiogenesis

    Cristiana Tanase, Elena Codrici, Irina Radu, Simona Mihai

    5. Apoptosis

    Cristiana Tanase, Radu Albulescu

    6. Signal transduction

    Cristiana Tanase, Monica Neagu, Radu Albulescu, Linda Maria Cruceru, Adrian Popa

    7. Stem cells markers in pituitary adenomas

    Corin Badiu, Cristiana Tanase, Linda Maria Cruceru

    8. microRNAs

    Cristiana Tanase, Radu Albulescu, Lucian Albulescu

    9. New generic tools for diagnosis: genomics, proteomics

    Cristiana Tanase, Radu Albulescu, Ionela Daniela Popescu

    10. Therapeutic approach: drug, surgical and radiotherapy

    Cristiana Tanase, Irina Ogrezeanu

Product details

  • No. of pages: 130
  • Language: English
  • Copyright: © Elsevier 2011
  • Published: October 31, 2011
  • Imprint: Elsevier
  • eBook ISBN: 9780124158528

About the Authors

Cristiana Tanase

Cristiana Tanase

Affiliations and Expertise

Victor Babes National Institute of Pathology, Bucharest, Romania

Irina Ogrezeanu

Affiliations and Expertise

"D. Bagdasar" Hospital, Bucharest, Romania

Corin Badiu

Affiliations and Expertise

"C.Davila" University of Medicine and Pharmacy and Institute of Endocrinology, Bucharest, Romania

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