Molecular Nutrition

Molecular Nutrition


1st Edition - August 23, 2019

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  • Editor: Vinood Patel
  • eBook ISBN: 9780128119365
  • Paperback ISBN: 9780128119075

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Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more. Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book.

Key Features

  • Summarizes molecular nutrition in health as related to vitamins
  • Includes material on signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis
  • Presents transcriptional processes, homeostasis genes, cancer, gene expression, mutations, the sodium-dependent multivitamin transporter, p53, p21, microRNAs, one carbon metabolism, nucleic acids, DNA methylation and polymorphisms
  • Addresses emerging fields of molecular biology and presents important discoveries related to diet and nutritional health
  • Covers Vitamins A, B, C, D, E, and K
  • Discusses their impact on health relating to cancer, diabetes, arthritis, and aging
  • Includes key facts, a mini dictionary of terms, and summary points


Researchers, professionals (including nutritionists, dieticians, health scientists, health care professionals, policy makers), educators, and students

Table of Contents

  • I General and Introductory Aspects
    1. Vitamin E: An Overview
    2. Requirements for Vitamins in Different Stages of the Life Cycle
    3. Vitamin C: Metabolism, Epigenetic Roles, and Cancer
    4. Riboflavin and Health: A Review
    5. A Review of Vitamin B12

    II Molecular Biology of the Cell
    6. Vitamin D Receptor in Arterial Ageing
    7. Tocotrienol Regulation of AMPK in Cancer
    8. Niacin and Hyperlipidemia
    9. Folate Transporters in Placentas
    10. Linking B-vitamins, Choline, and Stroke
    11. Riboflavin (Vitamin B2) and Mitochondrial Energy
    12. Pantothenic Acid (Vitamin B5) - Immunoreactive Neurons
    13. Ascorbic Acid (Vitamin C) and Alzheimer's Disease
    14. Vitamin B1 and the Pyruvate Dehydrogenase Complex
    15. Vitamin D and Diabetes Mellitus: Vitamin D Metabolism, Alterations of Vitamin D Endo-paracrine System and their Relation to Oxidative/Nitrosative Stress, Inflammation, and Cell survival
    16. Grape Seed Extract and Pyridoxine (Vitamin B6)
    17. Cobalamin (Vitamin B12) Malabsorption
    18. Pyridoxine (Vitamin B6) and Selenium Interactions: Implications for Human Health
    19. Linking Vitamin E and Nitric Oxide in Liver Disease
    20. Use of Methylcobalamin (Vitamin B12) in Pain
    21. New Properties of Vitamin B6 or Pyridoxine in Experimental Oxidative Stress in the Brain
    22. Thiamine (B1), Oxidative Stress, and Ethanol
    23. Vitamin E: Novel Metabolites and Treatments
    24. Vitamin E Structure and Forms/Analytical Methods
    25. Pyruvate Carboxylase (PC) and the Biotin Carboxylase Domain
    26. Application of Vitamins
    27. Vitamins in Chronic Kidney Disease
    28. Inflammatory Bowel Disorders and Fat-soluble Vitamins
    29. Vitamin E and Reproductive Health
    30. Vitamin B12 and Diabetes
    31. Biotin Status Screening
    32. Prostate Cancer and Applications of Vitamin K
    33. Non-alcoholic Fatty Liver Disease and Use of Folate
    34. Scenarios of Low Vitamin K Intakes

    III Genetic Machinery and its Function
    35. Transcriptional Control of Cells by Vitamin D
    36. Transcriptome Analysis for Vitamin B3 (Niacin) and its Receptor GPR109A
    37. Novel preventive mechanisms of vitamin B6 against inflammation, inflammasome, and chronic diseases
    38. Vitamins and Epigenetics

Product details

  • No. of pages: 792
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: August 23, 2019
  • Imprint: Academic Press
  • eBook ISBN: 9780128119365
  • Paperback ISBN: 9780128119075

About the Editor

Vinood Patel

Dr. Patel is a Reader at the University of Westminster. After completing his PhD at King’s College London, he continued his research experience by undertaking his post-doctoral studies in the laboratory of Professor Cunningham in the Department of Biochemistry at the Wake Forest University School of Medicine, (Winston-Salem, NC, USA). This extensive project involved investigating mechanisms of hepatic mitochondrial ribosome dysfunction in alcoholic liver disease (ALD) using biophysical and proteomic techniques. These studies have led to new avenues in determining the pathology of ALD. His teaching areas at both post-graduate and undergraduate levels include clinical biochemistry, investigative pathology and laboratory investigation.

Affiliations and Expertise

Reader in Clinical Biochemistry, University of Westminster, London, UK

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