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Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more.
Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book.
- Summarizes molecular nutrition in health as related to vitamins
- Includes material on signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis
- Presents transcriptional processes, homeostasis genes, cancer, gene expression, mutations, the sodium-dependent multivitamin transporter, p53, p21, microRNAs, one carbon metabolism, nucleic acids, DNA methylation and polymorphisms
- Addresses emerging fields of molecular biology and presents important discoveries related to diet and nutritional health
- Covers Vitamins A, B, C, D, E, and K
- Discusses their impact on health relating to cancer, diabetes, arthritis, and aging
- Includes key facts, a mini dictionary of terms, and summary points
Researchers, professionals (including nutritionists, dieticians, health scientists, health care professionals, policy makers), educators, and students
I General and Introductory Aspects
1. Vitamin E: An Overview
2. Requirements for Vitamins in Different Stages of the Life Cycle
3. Vitamin C: Metabolism, Epigenetic Roles, and Cancer
4. Riboflavin and Health: A Review
5. A Review of Vitamin B12
II Molecular Biology of the Cell
6. Vitamin D Receptor in Arterial Ageing
7. Tocotrienol Regulation of AMPK in Cancer
8. Niacin and Hyperlipidemia
9. Folate Transporters in Placentas
10. Linking B-vitamins, Choline, and Stroke
11. Riboflavin (Vitamin B2) and Mitochondrial Energy
12. Pantothenic Acid (Vitamin B5) - Immunoreactive Neurons
13. Ascorbic Acid (Vitamin C) and Alzheimer's Disease
14. Vitamin B1 and the Pyruvate Dehydrogenase Complex
15. Vitamin D and Diabetes Mellitus: Vitamin D Metabolism, Alterations of Vitamin D Endo-paracrine System and their Relation to Oxidative/Nitrosative Stress, Inflammation, and Cell survival
16. Grape Seed Extract and Pyridoxine (Vitamin B6)
17. Cobalamin (Vitamin B12) Malabsorption
18. Pyridoxine (Vitamin B6) and Selenium Interactions: Implications for Human Health
19. Linking Vitamin E and Nitric Oxide in Liver Disease
20. Use of Methylcobalamin (Vitamin B12) in Pain
21. New Properties of Vitamin B6 or Pyridoxine in Experimental Oxidative Stress in the Brain
22. Thiamine (B1), Oxidative Stress, and Ethanol
23. Vitamin E: Novel Metabolites and Treatments
24. Vitamin E Structure and Forms/Analytical Methods
25. Pyruvate Carboxylase (PC) and the Biotin Carboxylase Domain
26. Application of Vitamins
27. Vitamins in Chronic Kidney Disease
28. Inflammatory Bowel Disorders and Fat-soluble Vitamins
29. Vitamin E and Reproductive Health
30. Vitamin B12 and Diabetes
31. Biotin Status Screening
32. Prostate Cancer and Applications of Vitamin K
33. Non-alcoholic Fatty Liver Disease and Use of Folate
34. Scenarios of Low Vitamin K Intakes
III Genetic Machinery and its Function
35. Transcriptional Control of Cells by Vitamin D
36. Transcriptome Analysis for Vitamin B3 (Niacin) and its Receptor GPR109A
37. Novel preventive mechanisms of vitamin B6 against inflammation, inflammasome, and chronic diseases
38. Vitamins and Epigenetics
- No. of pages:
- © Academic Press 2019
- 23rd August 2019
- Academic Press
- eBook ISBN:
- Paperback ISBN:
Dr. Patel is a Reader at the University of Westminster. After completing his PhD at King’s College London, he continued his research experience by undertaking his post-doctoral studies in the laboratory of Professor Cunningham in the Department of Biochemistry at the Wake Forest University School of Medicine, (Winston-Salem, NC, USA). This extensive project involved investigating mechanisms of hepatic mitochondrial ribosome dysfunction in alcoholic liver disease (ALD) using biophysical and proteomic techniques. These studies have led to new avenues in determining the pathology of ALD. His teaching areas at both post-graduate and undergraduate levels include clinical biochemistry, investigative pathology and laboratory investigation.
Reader, University of Westminster, London, UK
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