Molecular Genetics Pt 2 - 1st Edition - ISBN: 9780126844023, 9780323146845

Molecular Genetics Pt 2

1st Edition

Editors: Herbert Taylor
eBook ISBN: 9780323146845
Imprint: Academic Press
Published Date: 1st January 1967
Page Count: 534
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Description

Molecular Genetics, Part II covers the significant developments in various areas of molecular genetics. This book is composed of 10 chapters that also consider the gene expression and regulation of some enzymes.

The opening chapters deal with the mechanisms of nucleic acid replication and repair, as well as the structural aspects of the genetic apparatus of viruses and cells. The next chapters explore the patterns and mechanisms of genetic recombination, the in vitro and in vivo experiments to delineate the genetic code, and the initiation of peptide chains in Escherichia coli. These topics are followed by discussions of the mechanism of DNA-dependent RNA synthesis, the regulation of enzyme synthesis in microorganisms, and the regulation of viral replication. The final chapters consider the theoretical and practical aspects of the metabolic regulation in metazoan system and the procedures for the study of DNA-DNA and DNA-RNA interactions.

This book will be of great value to molecular geneticists, biochemists, and researchers.

Table of Contents


Contributors To Part II


Preface


Contents Of Part I


Chapter I Mechanisms of Replication and Repair of Nucleic Acid


I. Introduction


II. Replication of DNA in Vitro


III. Replication of DNA in Vivo


IV. Damage and Repair of DNA


V. Effects of the Thymineless State


VI. Relation of DNA Replication to Protein Synthesis


VII. Single-Stranded DNA and RNA Phages


VIII. Conclusions


References


Chapter II Structural Aspects of the Genetic Apparatus of Viruses and Cells


I. Introduction


II. Nucleic Acids as Linear Macromolecules


III. Natural Nucleic Acids


IV. Circularity and Discontinuity in DNA


V. Replication of Nucleic Acids


VI. Structural Aspects of Organized Chromosomes


VII. Cytoplasmic Genetic Material


VIII. Models


IX. Conclusions


References


Chapter III Patterns and Mechanisms of Genetic Recombination


I. Introduction


II. Recombination in Bacteriophages


III. Genetic Transfer in Bacteria


IV. Recombination in Meiotic Divisions


V. Mechanisms of Genetic Recombination in Meiosis


VI. A Modified Chromosome Model with Some Implications for Recombination


VII. Addendum


References


Chapter IV The Genetic Code


I. Introduction


II. Deciphering the Code


References


Chapter V On Peptide Chain Initiation


I. Initiation of Peptide Chains in E. coli


II. On the Involvement of N-Formylmethionyl-tRNAF in Regulation


III. On Peptide Chain Initiation in Organisms Other Than E. coli


IV. Further Problems


V. Summary


References


Chapter VI RNA

Details

No. of pages:
534
Language:
English
Copyright:
© Academic Press 1967
Published:
Imprint:
Academic Press
eBook ISBN:
9780323146845

About the Editor

Herbert Taylor

Affiliations and Expertise

National Institutes of Health, Bethesda, Maryland, U.S.A.

Ratings and Reviews