Molecular Endocrinology

Introduction and General Endocrinology: Introduction. Classical Endocrinology. Non-Classical Endocrinology. Receptors: Kinetics. Nuclear Receptors. Membrane Receptors. Receptor Regulation. Transduction: G Proteins and Cyclic Nucleotides. Calcium, Calmodulin, and Phospholipids. Miscellaneous Second Messengers. Phosphorylation and Other Nontranscriptional Effects of Hormones. Gene Regulation by Hormones: Hormonally Regulated Transcription Factors. Modifications and Conformations of DNA and Nuclear Proteins. Posttranscriptional Control. Special Topics: Molecular Evolution of the Endocrine System. Pathogen-Endocrine System Interactions. Molecular Bases of Endocrinopathies. Subject Index.

Aimed at graduate level courses, this textbook provides students with a solid background in the basics of molecular endocrinology. Molecular Endocrinology, Second Edition, summarizes the area and provides an in-depth discussion of the molecular aspects of hormone action, including hormone-receptor interactions, second messenger generation, gene induction, and post-transcriptional control. Thoroughly revised and updated, the Second Edition includes new information on growth factors, hematopoietic-immune factors, nonclassical hormones, receptors, transduction, transcriptional regulation, as well as other relevant topics. Incorporating an abundance of new information, this text retains the self-contained, focused, and easily readable style of the First Edition. Professionals in related fields will also find this book to be a helpful summary and general reference source.

Students in endocrinology at the first-year graduate level (some seniors) and researchers wanting concise, accessible coverage.