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Molecular Diseases
FEBS Federation of European Biochemical Societies: 12th Meeting, Dresden, 1978
1st Edition - January 1, 1979
Editors: G. Jacobasch, S. Rapoport
Language: English
eBook ISBN:9781483188553
9 7 8 - 1 - 4 8 3 1 - 8 8 5 5 - 3
Molecular Diseases, Volume 56 presents the interrelated problems of synthesis, assembly, and breakdown of the various organelles of the cell for which powerful methods have been…Read more
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Molecular Diseases, Volume 56 presents the interrelated problems of synthesis, assembly, and breakdown of the various organelles of the cell for which powerful methods have been developed. This book discusses the processing of virus-coded proteins. Organized into nine chapters, this volume begins with an overview of the primary causes that can account for the hereditary defects of enzyme activity. This text then examines the basic methodological aspects of the assessment of protein turnover in a complex intact mammalian organism. Other chapters consider the method of desialylation of erythrocytes and their in vivo and in vitro behavior after this treatment. This book discusses as well the interrelationship between the peroxidatic enzymes and superoxide dismutase in the red cell. The final chapter deals with the use of liposomes as enzyme carriers in the treatment of lysosomal storage diseases. This book is a valuable resource for biological and medical students in various fields.
Preface
Molecular Basis of the Hereditary Defects of Enzyme Activity
Haemolytic Anaemia in Pyruvate Kinase Deficiency: Possibilities of Therapy
Membrane Desialylation and Elimination of Erythrocytes
Reactive Oxygen Metabolites and Haemolysis
Red Blood Cell Membrane Defects in β-Thalassemia and the Therapeutic Role of α-Tocopherol (Vitamin E)
Haemoglobin Precipitation and Red Cell Haemolysis
Reversion of HGPRT Deficiency of Skin Fibroblasts from Lesch-Nyhan Patients
Substitution Therapy in Lysosomal Storage Diseases
Introduction of Enzymes into Liver Cells by Means of Liposomes