Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein folding and ligand-acceptor interactions are included in Volumes 202 and 203, as are genetic and chemical methods for the production of functional molecules including antibodies and antigens, enzymes, receptors, nucleic acids and polysaccharides, and drugs.
Biochemists, cell biologists, molecular biologists, developmental biologists, geneticists, and biophysicists.
Antibodies and Antigens: Antibody Combining Site:
E.A. Padlan and E.A. Kabat, Modeling of Antibody Combining Sites.
M.B. Bolger and M.A. Sherman, Computer Modeling of the Combining Site Structure of Anti-hapten Monoclonal Antibodies.
J.S. Huston, M. Mudgett-Hunter, M.-S. Tai, J. McCartney, F. Warren, E. Haber, and H. Oppermann, Protein Engineering of Single-Chain Fv Analogs and Fusion Proteins.
S. Johnson and R.E. Bird, Construction of Single-Chain Fv Derivatives of Monoclonal Antibodies and Their Production in Escherichia coli.
D. G~adussow and G. Seemann, Humanization of Monoclonal Antibodies.
A.C.R. Martin, J.C. ~Cheetham, and A. Rees, Molecular Modeling of Antibody Combining Sites.
I.A. Wilson, J.M. Rini, D.H. Fremont, G.G. Fieser, and E.A Stura, X-Ray Crystallographic Analysis of Free and Antigen-Complexed Fab Fragments to Investigate Structural Basis of Immune Recognition.
J.L. Pellequer, E. Westhof, and M.H.V. Van Regenmortel, Predicting Location of Continuous Epitopes in Proteins from Their Primary Structures.
J.C. Cheetham, C. Redfield, R.E. Griest, C.M. Dobson, and A.R. Rees, Use of Two-Dimensional 1H Nuclear Magnetic Resonance to Study High-Affinity Antibody-Peptide Interactions.
J. Anglister and F. Naider, Nuclear Magnetic Resonance for Studying Peptide-Antibody Complexes by Transferred Nuclear Overhauser Effect Difference Spectroscopy.
P. Tsang, M. Rance, and P.E. Wright, ~Isotope-Edited Nuclear Magnetic Resonance Studies of Fab-Peptide Complexes.
J.E. Jentoft, Reductive Methylation and Carbon-13 Nuclear Magnetic Resonance in Structure-Function Studies of the Fc Fragment and Its Subfragments.
- No. of pages:
- © Academic Press 1991
- 1st November 1991
- Academic Press
- eBook ISBN:
- Hardcover ISBN:
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