Molecular Design and Modeling: Concepts and Applications, Part A: Proteins, Peptides, and Enzymes, Volume 202

1st Edition

Print ISBN: 9780121821036
eBook ISBN: 9780080883175
Imprint: Academic Press
Published Date: 9th October 1991
Page Count: 824

Institutional Access


Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein folding and ligand-acceptor interactions are included in Volumes 202 and 203, as are genetic and chemical methods for the production of functional molecules including antibodies and antigens, enzymes, receptors, nucleic acids and polysaccharides, and drugs.


Biochemists, cell biologists, molecular biologists, geneticists, immunologists, pharmocologists, biophysicists, and endocrinologists in academia and industry.

Table of Contents

Proteins and Peptides: Principles and Methods: Protein Folding, Stability, and Function:

N.M. Allewell and H. Oberoi, Electrostatic Effects in Protein Folding, Stability, and Function.

C. Lawrence and S. Bryant, Hydrophobic Potentials from Statistical Analysis of Protein Structures.

K. Nishikawa and T. Noguchi, Predicting Protein Secondary Structure Based on Amino Acid Sequence.

T. Niermann and K. Kirschner, Use of Homologous Sequences to Improve Protein Secondary Structure Prediction.

B.L. Sibanda and J.M. Thornton, Conformation of ~gb-Hairpins in Protein Structures: Classification and Diversity in Homologous Structures.

A. Matouschek and A.R. Fersht, Protein Engineering in the Analysis of Protein Folding Pathways and Stability.

P.A. ~Jennings, S.M. Saalau-Bethell, B.E. Finn, X. Chen, and C.R. Matthews, Mutational Analysis of Protein Folding Mechanisms.

Design and Modeling:

R.A. Lewis, Clefts and Binding Sites in Protein Receptors.

N. Summers and M. Karplus, Modeling of Side Chains, Loops, and Insertions.

L.H. Holley and M. Karplus, Neural Networks.

V.E. Reyes, R.A. Lew, S. Lu, and R.E. Humphreys, Prediction of ~ga Helices and T-Cell-Presented Sequences in Proteins with Algorithms Based on Strip-of-Helix Hydrophobicity Index.

J. Greer, Comparative Modeling of Homologous Proteins.

B.I. Cohen, S.R. Presnell, and F.E. Cohen, Pattern-Based Approaches to Protein Structure Prediction.

J. de Vlieg and W.F. van Gunsteren, Combined Procedures of Distance Geometry and Molecular Dynamics ~for Determining Protein Structure from NMR Data.

J. Ellman, S. Anthony-Cahill, C.J. Noren, and P.G. Schultz, Biosynthet


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© Academic Press 1991
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