Molecular Control of Proliferation and Differentiation

Molecular Control of Proliferation and Differentiation documents the proceedings of the 35th symposium of The Society for Developmental Biology entitled "Molecular Control of Proliferation and Differentiation," held at Asilomar, Monterey Peninsula, California, June 8-11, 1976. The contributions made by researchers at the symposium are organized into seven parts. Part I presents a paper on cell communication in embryological development. Part II includes studies on growth factors, including fibroblast growth factor and epidermal growth factor. Part III examines the factors affecting nerve cell differentiation and function. It includes papers on nerve growth factor and peptides as central nervous system neurotransmitters. Part IV focuses on cell interactions in blood cell development. It includes studies on factors affecting the differentiation of blood cells and the proliferation of hemopoietic stem cells in vitro. Part V examines cell interactions in the immune system. Part VI deals with cell interactions in organogenesis. Part VII covers the factors effecting differentiation in lower eukaryotes.

List of Contributors

Foreword

I. Introduction

Cell Communication in Embryological Development: The Role of Distal and Proximal Signals

II. Growth Factors

Biological and Molecular Studies of the Mitogenic Effects of Human Epidermal Growth Factor

Cellular Specificities of Fibroblast Growth Factor and Epidermal Growth Factor

Growth Control by Serum Factors and Hormones in Mammalian Cells in Culture

III. Factors Affecting Nerve Cell Differentiation and Function

Nerve Growth Factor: Studies on the Localization, Regulation, and Mechanism of Its Biosynthesis

Nerve Growth Factor as a Mediator of Information between Effector Organs and Innervating Neurons

Peptides as Central Nervous System Neurotransmitters

IV. Cell Interactions in Blood Cell Development

Factors Affecting the Differentiation of Blood Cells

Factors Controlling the Proliferation of Haemopoietic Stem Cells in Vitro

Aspects of Erythroid Differentiation and Proliferation

The Role of Factors in Differentiation of Non-Erythroid Cells

V. Cell Interactions in the Immune System

Cell Interactions in Cell Mediated Immunity

Lymphocyte Differentiations Induced by Thymopoietin, Bursopoietin, and Ubiquitin

VI. Cell Interactions in Organogenesis

An Analysis of Pancreatic Development: Role of Mesenchymal Factor and Other Extracellular Factors

VII. Factors Effecting Differentiation in Lower Eukaryotes

Action of a Morphogenetic Substance from Hydra

Mating-Type Specific Pheromones as Mediators of Sexual Conjugation in Yeast

Index