Molecular Biology of Placental Development and Disease

Molecular Biology of Placental Development and Disease

1st Edition - January 1, 2017
  • Editor: William Huckle
  • eBook ISBN: 9780128096024
  • Hardcover ISBN: 9780128093276

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Description

Molecular Biology of Placental Development and Disease, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on placental development and disease.

Key Features

  • Contains contributions from leading authorities on the topic of placental development and disease
  • Publishes cutting-edge reviews in molecular biology

Readership

Students, researchers, microbiologists, molecular biologists

Table of Contents

  • Chapter One: Comparative Placental Anatomy: Divergent Structures Serving a Common Purpose

    • Abstract
    • The Placenta
    • 1 Fetal Membranes
    • 2 Classification of Placentae
    • 3 Placenta of Humans
    • 4 Placenta of Rodents
    • 5 Placenta of Carnivores
    • 6 Placenta of Ruminants
    • 7 Placenta of the Horse
    • 8 Placenta of the Pig
    • 9 Placental Vasculature
    • 10 Summary

    Chapter Two: Cell- and Tissue-Based Models for Study of Placental Development

    • Abstract
    • 1 Introduction
    • 2 Simplified ex vivo Models
    • 3 Conclusions and Future Prospects

    Chapter Three: Transcription Factors That Regulate Trophoblast Development and Function

    • Abstract
    • 1 Introduction
    • 2 Transcription Factors Implicated in Trophoblast Development
    • 3 Conclusions
    • Acknowledgments

    Chapter Four: The Phylogeny of Placental Evolution Through Dynamic Integrations of Retrotransposons

    • Abstract
    • 1 Placenta: Structural Diversity
    • 2 Placenta ERVs
    • 3 Hypothesis of Gene Evolution Through Baton Pass
    • 4 Concluding Remarks

    Chapter Five: Contribution of Syncytins and Other Endogenous Retroviral Envelopes to Human Placenta Pathologies

    • Abstract
    • 1 Introduction
    • 2 So Many Human Endogenous Retroviral Loci, so Few Genes Encoding Envelopes
    • 3 Syncytin-1
    • 4 Deregulation of Syncytin-1 in Human Placenta Pathologies
    • 5 Conclusion
    • Acknowledgment

    Chapter Six: Role of Exosomes in Placental Homeostasis and Pregnancy Disorders

    • Abstract
    • 1 Introduction
    • 2 Influence of Oxygen Tension on Placental Exosomes Release and Content
    • 3 Effects of Placental Exosomes on Target Cells
    • 4 Circulating Exosomes Across Normal Gestation
    • 5 Exosomal Profile in GDM Pregnancies
    • 6 Exosomal Profile in PE
    • 7 Conclusions and Perspectives

    Chapter Seven: Novel Regulators of Hemodynamics in the Pregnant Uterus

    • Abstract
    • 1 Introduction
    • 2 An Overview of Vascular Remodeling During Pregnancy
    • 3 Regulators of Uterine Hemodynamics
    • 4 Uterine Hemoglobin Biosynthesis During Gestation
    • 5 Concluding Remarks
    • Acknowledgments

    Chapter Eight: Regulation of Placental Amino Acid Transport and Fetal Growth

    • Abstract
    • 1 Introduction
    • 2 Placental Amino Acid Transport and Fetal Growth
    • 3 Physiological Regulators of Placental Amino Acid Transport
    • 4 Molecular Mechanisms Underlying Regulation of Placental Amino Acid Transport
    • 5 Conclusions and Translational Perspectives

Product details

  • No. of pages: 274
  • Language: English
  • Copyright: © Academic Press 2017
  • Published: January 1, 2017
  • Imprint: Academic Press
  • eBook ISBN: 9780128096024
  • Hardcover ISBN: 9780128093276

About the Serial Volume Editor

William Huckle

Dr. William Huckle works at the Department of Biomedical Sciences & Pathobiology, Virginia Tech,USA.

Affiliations and Expertise

Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA