Molecular Biology of Neurodegenerative Diseases

Molecular Biology of Neurodegenerative Diseases

1st Edition - April 13, 2012

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  • Editor: David Teplow
  • Hardcover ISBN: 9780123858832
  • eBook ISBN: 9780123858849

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Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Parkinson’s, Alzheimer’s and Huntington’s disease. Much research is taking place to try to identify ways to prevent or lessen the impact of these diseases. This volume reviews the latest research and developments in the molecular biology of neurodegenerative diseases.

Key Features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field


Researchers in molecular biology, biochemistry, cell biology and genetics

Table of Contents

    1. Neuropathology and imaging
    2. Harry Vinters

    3. Neuropathology and imaging
    4. Thompson, Paul

    5. Age-dependence of neurodegenerative diseases (organismal genetics)
    6. Tanzi, Rudolph

    7. AD
    8. Dominic Walsh

    9. PD
    10. Guo, Ming

    11. PD
    12. Rochet, Chris and

    13. Prion I: Human
    14. Surewicz, Witold

    15. Prion II: Yeast
    16. Tuite, Mick

    17. Cerebral amyloid angiopathy Cerebral amyloid angiopathy
    18. Yamada, Masahito Naiki, Hironobu Tau, and Gloria Lee

    19. Membrane Pores
    20. Kagan, Bruce

    21. Unfolded protein response
    22. ALS
    23. Dokholyan, Nikolay

    24. CAG-repeat diseases
    25. Chris Ross

    26. Mitochondria

    Lee Martin

Product details

  • No. of pages: 498
  • Language: English
  • Copyright: © Academic Press 2012
  • Published: April 13, 2012
  • Imprint: Academic Press
  • Hardcover ISBN: 9780123858832
  • eBook ISBN: 9780123858849

About the Serial Volume Editor

David Teplow

David Teplow
Professor Teplow is a member of the Department of Neurology, David Geffen School of Medicine at UCLA; Director, UCLA Biopolymer Laboratory; and a member of the faculties of the Molecular Biology Institute, Brain Research Institute, Chemistry-Biology Interface Training Program, and various neuroscience graduate programs. Professor Teplow received degrees in Biochemistry, and in Bacteriology & Immunology, from UC Berkeley; a Ph.D. from the University of Washington, Seattle; and postdoctoral training at the California Institute of Technology, Pasadena, CA. From 1991-2005, Professor Teplow was a member of the faculty of the Department of Neurology, Harvard Medical School, Boston. Professor Teplow has published >200 peer-reviewed articles, including ~150 original articles and ~50 reviews, book chapters, and commentaries. Professor Teplow was a founding editor of the Journal of Molecular Neuroscience and Current Chemical Biology. He currently is Associate Editor-in-Chief of the American Journal of Neurodegenerative Disease. Professor Teplow is a member of numerous national and international scientific advisory and editorial boards.

Affiliations and Expertise

Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA

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