Molecular Basis of Neuropsychiatric Disorders: from Bench to Bedside

Molecular Basis of Neuropsychiatric Disorders: from Bench to Bedside

1st Edition - October 5, 2019
  • Editor: Shafiqur Rahman
  • eBook ISBN: 9780128188569
  • Hardcover ISBN: 9780128188552

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Progress in Molecular Biology and Translational Science, Volume 167, provides the most topical, informative and exciting monographs available on a wide variety of research topics related to Models and Biological Targets in Drug Discovery for Attention Deficit Hyperactivity Disorder, Novel Targets for Parkinson-Depression Co-morbidity. Utility of Cannabidiol (CBD) in Neuropsychiatric Disorders: A Short Review of the Recent Pre-clinical and Clinical Findings, The Many Sides of Microglia in Alcohol Use Disorders, Stress, Anxiety, Molecular Targets and More, Calcineurin Signaling in Psychiatric Disorders, Emerging Evidence for the Role of Pituitary Adenylate Cyclase- Activating Peptide (PACAP) in Neuropsychiatric Disorders, and more.

Key Features

  • Includes comprehensive coverage of molecular biology
  • Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided
  • Contains contributions from renowned experts in the field


Each volume of Progress in Molecular Biology and Translational Science will be useful for scientists working actively in a field, including those at levels ranging from graduate student to senior investigator. Volumes are also appropriate for new investigators to a field who wish to familiarize themselves with the latest work

Table of Contents

  • 1. Novel targets for parkinsonism-depression comorbidity
    Yousef Tizabi, Bruk Getachew, Antonei B. Csoka, Kebreten F. Manaye and Robert L. Copeland
    2. Effects of cannabidiol (CBD) in neuropsychiatric disorders: A review of pre-clinical and clinical findings
    Sonja Elsaid, Stefan Kloiber and Bernard Le Foll
    3. Stress, psychiatric disorders, molecular targets, and more
    Fatin Atrooz, Hesong Liu and Samina Salim
    4. Calpain in the cleavage of alpha-synuclein and the pathogenesis of Parkinson's disease
    Ramsha Shams, Naren L. Banik and Azizul Haque
    5. Calcineurin signaling as a target for the treatment of alcohol abuse and neuroinflammatory disorders
    Patrick J. Ronan, Sarah A. Flynn and Thomas P. Beresford
    6. Emerging evidence for the role of pituitary adenylate cyclase-activating peptide in neuropsychiatric disorders
    Kabirullah Lutfy and Shankar Gollapudi
    7. Glial mechanisms underlying major depressive disorder: Potential therapeutic opportunities
    Shafiqur Rahman and Sami Alzarea
    8. Its complicated: The relationship between alcohol and microglia in the search for novel pharmacotherapeutic targets for alcohol use disorders
    Jennifer K. Melbourne, K. Ryan Thompson, Hui Peng and Kimberly Nixon
    9. Microglia as possible therapeutic targets for autism spectrum disorders
    Megumi Andoh, Yuji Ikegaya and Ryuta Koyama

Product details

  • No. of pages: 266
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: October 5, 2019
  • Imprint: Academic Press
  • eBook ISBN: 9780128188569
  • Hardcover ISBN: 9780128188552

About the Editor

Shafiqur Rahman

Shafiqur Rahman
Shafiqur Rahman, Ph.D. is Professor of Pharmacology in the Department of Pharmaceutical Sciences at South Dakota State University (SDSU) in Brookings, USA. He received his Ph.D. in Neuropharmacology from the Memorial University of Newfoundland, Canada. Dr. Rahman completed his post-doctoral fellowship in the Department of Psychiatry from Indiana University School of Medicine in Indianapolis in USA. Prior to joining SDSU, he worked as research scientist and faculty at the University of Kentucky in Lexington, USA and the University of Toronto, Canada.

Dr. Rahman's research focus is drug discovery in neuropharmacology, i.e. the development of novel therapeutic candidates for the treatment of alcohol/nicotine addiction and neuropsychiatric disorders using animal models. His research resulted in over 200 publications/presentations, including peer-reviewed scientific articles, reviews, book chapters, meeting abstracts and seminar presentations. Dr. Rahman served on numerous scientific review panels and editorial boards of several scientific Journals. He has authored or edited multiple books or Journals in drug addiction and neuropharmacology field. Dr. Rahman is also affiliated with a number of professional organizations, including Society for Neuroscience and American Society for Pharmacology and Experimental Therapeutics.

Affiliations and Expertise

Professor, Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD, USA