Molecular Basis of Biological Degradative processes - 1st Edition - ISBN: 9780120921508, 9780323155045

Molecular Basis of Biological Degradative processes

1st Edition

Editors: Richard Berlin
eBook ISBN: 9780323155045
Imprint: Academic Press
Published Date: 1st January 1978
Page Count: 344
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Description

Molecular Basis of Biological Degradative Processes contains the proceedings of the 1977 symposium held at the University of Connecticut Health Science Center. The papers focus on the molecular mechanisms underlying the biological degradation, including the relationship between the lysosome and tissue remodeling and the role of this organelle in processing intra- and extracellular material. The book also explores the specific application of the lysosome concept to the description of deficiency diseases of lipid catabolism. Organized into 12 chapters, this book begins with an overview of the mechanisms underlying cell death and its control, along with possible experimental models for its study, nutrient deficiencies during prenatal development, and congenital diseases resulting from zinc, magnesium, and manganese deficiencies. It explains the clinical lysosome deficiencies, the early phase of blood coagulation, cascade events in the activation and function of mast cells, activation of plasminogen and its involvement in the production of localized extracellular proteolysis, and proteolytic events in viral replication. Chapters on human neutrophil elastase and the protease-pathogenesis model of pulmonary emphysema; dissolution mechanism of apatite crystals during dental caries and bone resorption; and degradative processes of bone follow. This book is a valuable resource for biologists, physiologists, and those involved in basic and applied research in ""catabolic"" processes.

Table of Contents


Contributors

Preface

Developing Organisms as Model Systems for the Study of Degradative Processes

An Integrated View of Lysosome Function

Elucidation of Clinical Lysosome Deficiencies

Complement: Molecular Mechanisms, Regulation, and Biologic Function

The Early Phase of Blood Coagulation

Cascade Events in Mast Cell Activation and Function

Activation of Plasminogen: A General Mechanism for Producing Localized Extracellular Proteolysis

Proteolytic Events in Viral Replication

Human Neutrophil Elastase and the Protease-Pathogenesis Model of Pulmonary Emphysema

Dental Caries

Dissolution Mechanism of the Apatite Crystals during Dental Caries and Bone Resorption

Degradative Processes of Bone






Details

No. of pages:
344
Language:
English
Copyright:
© Academic Press 1978
Published:
Imprint:
Academic Press
eBook ISBN:
9780323155045

About the Editor

Richard Berlin