Molecular Basis of Aging - 1st Edition - ISBN: 9780126010602, 9780323151559

Molecular Basis of Aging

1st Edition

Editors: A Roy
eBook ISBN: 9780323151559
Imprint: Academic Press
Published Date: 28th January 1984
Page Count: 410
Sales tax will be calculated at check-out Price includes VAT/GST
Price includes VAT/GST
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.


Molecular Basis of Aging is a collection of papers that discuss the molecular aspects of aging in the light of molecular biology, biochemical gerontology, and genetics. Each chapter of the book contains a different study about the topic, which includes the effects of aging on DNA synthesis; the amplification of extrachromosomal circular copies and mitochondrial DNA during aging; and the altered actions of hormones and neurotransmitters during aging. The book also encompasses the loss of responsiveness to growth factors in cell senescence; the integration of cellular-molecular and neuroendocrine concepts of aging; changes and inactivation of enzymes during aging; and the relationship of aging with free radicals. The text is recommended for molecular biologists, biochemists, and gerontologists who wish to study further the effects of aging on the body on a molecular level.

Table of Contents

Contributors Preface Amplification of Extrachromosomal Circular Copies of an Inter-Alu Unstable DNA Sequence during in Vitro and in Vivo Aging Site-Specific Excision-Amplification of Mitochondrial DNA 29 during Senescence in Podospora anserina Fidelity of DNA Synthesis during Aging DNA Excision Repair in Aging Inbred Rats DNA Synthesis, Cell Progression, and Aging in Human Diploid Fibroblasts Loss of Responsiveness to Growth Factors in Cell Senescence Hormonal Regulation of Hepatic Gene Expression during Aging Altered Hormone/Neurotransmitter Action during Aging: Receptor and Post-Receptor Changes Cellular-Molecular versus Neuroendocrine Concepts of Aging: A Need for Integration Changes in Enzymatic Proteins during Aging Oxidative Inactivation of Key Metabolie Enzymes during Aging Free Radicals and Aging Mathematics of Molecular Aging Mechanisms Index


No. of pages:
© Academic Press 1984
Academic Press
eBook ISBN:

About the Editor

A Roy

Ratings and Reviews