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molecular Approaches to Immunology - 1st Edition - ISBN: 9780126510508, 9780323153966

molecular Approaches to Immunology

1st Edition

Editor: E.E. Smith
eBook ISBN: 9780323153966
Imprint: Academic Press
Published Date: 1st January 1975
Page Count: 366
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Molecular Approaches to Immunology is the 9th volume of the series ""Miami Winter Symposia"". This volume presents papers that cover various aspects about cellular and modern immunology. Cellular immunology deals with the interactions of cells and molecules of the immune system and how these interactions help eliminate pathogens. The main goal of this book is to discuss and provide basic assumptions, approaches, and direction about the advances in the research of immunological science. In relation to this, the chapters of the book examine the recognition of antigen by T-lymphocytes, the role of cell interactions in determining the immune responsiveness, and the concepts behind clonal selection. The book also explains the different genes coding used for antibodies and the characterization of cell surface receptors at molecular level. Furthermore, it examines the evidences for genetic restrictions in cell interactions and the chemical properties of thymosin used in physiological studies. Discussions on the immunoregulation and immunological tolerance by T cells and the growth control of mammalian cells are also presented in this volume. This compilation will be invaluable to biologists, medical practitioners, professors, and students.

Table of Contents

Speakers, Chairmen, and Discussants


The Sixth Feodor Lynen Lecture

The Shock of Molecular Recognition


The Subject and Style of Modern Immunology: An Introduction

Current Concepts in Cellular Immunology


Recognition of Antigen by T Lymphocytes


The Logic of Cell Interactions in Determining Immune Responsiveness


The Use of Mutant Myeloma Cells to Explore the Production of Immunoglobulins


Immunoglobulin Genes in a Mouse Myeloma and in Mutant Clones


Genes Coding for Antibodies


The Organization and Diversity of Immunoglobulin κ and γ Genes


Cell Surface Antigens and Cell Surface Proteins


The Role of Products of the Histocompatibility Gene Complex in Immune Responses


The Role of Thymosin and the Endocrine Thymus on the Ontogenesis and Function of T-Cells


Immunoregulation by T Cells


Control of Growth of Mammalian Cells


Restricted Clonal Responses: A Tool in Understanding Antibody Specificity


Poster Session: Communications

Repetitive Hinge Region Sequences in a γ3 Heavy Chain Disease Protein-Isolation of an 11,000 Dalton Fragment

Structural Characterization of a Mutant Human Lambda Immunoglobulin Type L-Chain

Heterogeneity of the C-Region of an IgGl Immunoglobulin: The Structure of γ-Heavy Chain Disease Protein Baz

Growth Factor for a Viral Transformed Cell From Rat Liver and Hemicorpus Perfusions

Lymphocyte Responses to Mitogens and Antigens in Agarose-Gel Cultures

Sterol Synthesis in Normal, Phytohemagglutinin-Stimulated, and Leukemic Mouse Lymphocytes

Can Protein Synthesis in Cultured Cells Be Regulated by Membrane- Mediated Events?

Alteration of Membrane Antigens by Trypsin

IgM Complex Receptors on T and B Lymphocytes

B and T Lymphocytes in Dysgammaglobulinemia

The Role of Thymic Extract in Transfer of Delayed Hypersensitivity (D.H.S.) and Immunostimulation

Growth Properties and Alloantigenic Expression of Murine Lymphoblastic Cell Lines Grown in Suspension Culture

Regulation of Ab Activity of Rabbit (Rab) Ig+Lymphocytes (LC) by Products of Rab Ig⁻LC

Evidence for the Genetic Control of Antigenic Modulation

The Response of Congenitally Athymic (NUDE) Mice to Infection with Mycobacterium bovis (Strain BCG)

Nonspecific Stimulators of the Immune System


No. of pages:
© Academic Press 1975
1st January 1975
Academic Press
eBook ISBN:

About the Editor

E.E. Smith

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