molecular Approaches to Immunology - 1st Edition - ISBN: 9780126510508, 9780323153966

molecular Approaches to Immunology

1st Edition

Editors: E.E. Smith
eBook ISBN: 9780323153966
Imprint: Academic Press
Published Date: 1st January 1975
Page Count: 366
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Molecular Approaches to Immunology is the 9th volume of the series ""Miami Winter Symposia"". This volume presents papers that cover various aspects about cellular and modern immunology. Cellular immunology deals with the interactions of cells and molecules of the immune system and how these interactions help eliminate pathogens.
The main goal of this book is to discuss and provide basic assumptions, approaches, and direction about the advances in the research of immunological science. In relation to this, the chapters of the book examine the recognition of antigen by T-lymphocytes, the role of cell interactions in determining the immune responsiveness, and the concepts behind clonal selection. The book also explains the different genes coding used for antibodies and the characterization of cell surface receptors at molecular level. Furthermore, it examines the evidences for genetic restrictions in cell interactions and the chemical properties of thymosin used in physiological studies. Discussions on the immunoregulation and immunological tolerance by T cells and the growth control of mammalian cells are also presented in this volume. This compilation will be invaluable to biologists, medical practitioners, professors, and students.

Table of Contents

Speakers, Chairmen, and Discussants Preface The Sixth Feodor Lynen Lecture The Shock of Molecular Recognition Introduction The Subject and Style of Modern Immunology: An Introduction Current Concepts in Cellular Immunology Discussion Recognition of Antigen by T Lymphocytes Discussion The Logic of Cell Interactions in Determining Immune Responsiveness Discussion The Use of Mutant Myeloma Cells to Explore the Production of Immunoglobulins Discussion Immunoglobulin Genes in a Mouse Myeloma and in Mutant Clones Discussion Genes Coding for Antibodies Discussion The Organization and Diversity of Immunoglobulin κ and γ Genes Discussion Cell Surface Antigens and Cell Surface Proteins Discussion The Role of Products of the Histocompatibility Gene Complex in Immune Responses Discussion The Role of Thymosin and the Endocrine Thymus on the Ontogenesis and Function of T-Cells Discussion Immunoregulation by T Cells Discussion Control of Growth of Mammalian Cells Discussion Restricted Clonal Responses: A Tool in Understanding Antibody Specificity Discussion Poster Session: Communications Repetitive Hinge Region Sequences in a γ3 Heavy Chain Disease Protein-Isolation of an 11,000 Dalton Fragment Structural Characterization of a Mutant Human Lambda Immunoglobulin Type L-Chain Heterogeneity of the C-Region of an IgGl Immunoglobulin: The Structure of γ-Heavy Chain Disease Protein Baz Growth Factor for a Viral Transformed Cell From Rat Liver and Hemicorpus Perfusions Lymphocyte Responses to Mitogens and Antigens in Agarose-Gel Cultures Sterol Synthesis in Normal, Phytohemagglutinin-Stimulated, and Leukemic Mouse Lymphocytes Can Protein Synthesis in Cultured Cells Be Regulated by Membrane- Mediated Events? Alteration of Membrane Antigens by Trypsin IgM Complex Receptors on T and B Lymphocytes B and T Lymphocytes in Dysgam


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© Academic Press 1975
Academic Press
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E.E. Smith

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