molecular Approaches to Immunology

molecular Approaches to Immunology

1st Edition - January 1, 1975

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  • Editor: E.E. Smith
  • eBook ISBN: 9780323153966

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Description

Molecular Approaches to Immunology is the 9th volume of the series ""Miami Winter Symposia"". This volume presents papers that cover various aspects about cellular and modern immunology. Cellular immunology deals with the interactions of cells and molecules of the immune system and how these interactions help eliminate pathogens. The main goal of this book is to discuss and provide basic assumptions, approaches, and direction about the advances in the research of immunological science. In relation to this, the chapters of the book examine the recognition of antigen by T-lymphocytes, the role of cell interactions in determining the immune responsiveness, and the concepts behind clonal selection. The book also explains the different genes coding used for antibodies and the characterization of cell surface receptors at molecular level. Furthermore, it examines the evidences for genetic restrictions in cell interactions and the chemical properties of thymosin used in physiological studies. Discussions on the immunoregulation and immunological tolerance by T cells and the growth control of mammalian cells are also presented in this volume. This compilation will be invaluable to biologists, medical practitioners, professors, and students.

Table of Contents


  • Speakers, Chairmen, and Discussants

    Preface

    The Sixth Feodor Lynen Lecture

    The Shock of Molecular Recognition

    Introduction

    The Subject and Style of Modern Immunology: An Introduction

    Current Concepts in Cellular Immunology

    Discussion

    Recognition of Antigen by T Lymphocytes

    Discussion

    The Logic of Cell Interactions in Determining Immune Responsiveness

    Discussion

    The Use of Mutant Myeloma Cells to Explore the Production of Immunoglobulins

    Discussion

    Immunoglobulin Genes in a Mouse Myeloma and in Mutant Clones

    Discussion

    Genes Coding for Antibodies

    Discussion

    The Organization and Diversity of Immunoglobulin κ and γ Genes

    Discussion

    Cell Surface Antigens and Cell Surface Proteins

    Discussion

    The Role of Products of the Histocompatibility Gene Complex in Immune Responses

    Discussion

    The Role of Thymosin and the Endocrine Thymus on the Ontogenesis and Function of T-Cells

    Discussion

    Immunoregulation by T Cells

    Discussion

    Control of Growth of Mammalian Cells

    Discussion

    Restricted Clonal Responses: A Tool in Understanding Antibody Specificity

    Discussion

    Poster Session: Communications

    Repetitive Hinge Region Sequences in a γ3 Heavy Chain Disease Protein-Isolation of an 11,000 Dalton Fragment

    Structural Characterization of a Mutant Human Lambda Immunoglobulin Type L-Chain

    Heterogeneity of the C-Region of an IgGl Immunoglobulin: The Structure of γ-Heavy Chain Disease Protein Baz

    Growth Factor for a Viral Transformed Cell From Rat Liver and Hemicorpus Perfusions

    Lymphocyte Responses to Mitogens and Antigens in Agarose-Gel Cultures

    Sterol Synthesis in Normal, Phytohemagglutinin-Stimulated, and Leukemic Mouse Lymphocytes

    Can Protein Synthesis in Cultured Cells Be Regulated by Membrane- Mediated Events?

    Alteration of Membrane Antigens by Trypsin

    IgM Complex Receptors on T and B Lymphocytes

    B and T Lymphocytes in Dysgammaglobulinemia

    The Role of Thymic Extract in Transfer of Delayed Hypersensitivity (D.H.S.) and Immunostimulation

    Growth Properties and Alloantigenic Expression of Murine Lymphoblastic Cell Lines Grown in Suspension Culture

    Regulation of Ab Activity of Rabbit (Rab) Ig+Lymphocytes (LC) by Products of Rab Ig⁻LC

    Evidence for the Genetic Control of Antigenic Modulation

    The Response of Congenitally Athymic (NUDE) Mice to Infection with Mycobacterium bovis (Strain BCG)

    Nonspecific Stimulators of the Immune System






Product details

  • No. of pages: 366
  • Language: English
  • Copyright: © Academic Press 1975
  • Published: January 1, 1975
  • Imprint: Academic Press
  • eBook ISBN: 9780323153966

About the Editor

E.E. Smith

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