molecular Approaches to Immunology

1st Edition - January 1, 1975
Editor: E.E. Smith
Language: English
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 1 5 3 9 6 - 6

Molecular Approaches to Immunology is the 9th volume of the series ""Miami Winter Symposia"". This volume presents papers that cover various aspects about cellular and modern… Read more

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Molecular Approaches to Immunology is the 9th volume of the series ""Miami Winter Symposia"". This volume presents papers that cover various aspects about cellular and modern immunology. Cellular immunology deals with the interactions of cells and molecules of the immune system and how these interactions help eliminate pathogens. The main goal of this book is to discuss and provide basic assumptions, approaches, and direction about the advances in the research of immunological science. In relation to this, the chapters of the book examine the recognition of antigen by T-lymphocytes, the role of cell interactions in determining the immune responsiveness, and the concepts behind clonal selection. The book also explains the different genes coding used for antibodies and the characterization of cell surface receptors at molecular level. Furthermore, it examines the evidences for genetic restrictions in cell interactions and the chemical properties of thymosin used in physiological studies. Discussions on the immunoregulation and immunological tolerance by T cells and the growth control of mammalian cells are also presented in this volume. This compilation will be invaluable to biologists, medical practitioners, professors, and students.

Speakers, Chairmen, and Discussants

Preface

The Sixth Feodor Lynen Lecture

The Shock of Molecular Recognition

Introduction

The Subject and Style of Modern Immunology: An Introduction

Current Concepts in Cellular Immunology

Discussion

Recognition of Antigen by T Lymphocytes

Discussion

The Logic of Cell Interactions in Determining Immune Responsiveness

Discussion

The Use of Mutant Myeloma Cells to Explore the Production of Immunoglobulins

Discussion

Immunoglobulin Genes in a Mouse Myeloma and in Mutant Clones

Discussion

Genes Coding for Antibodies

Discussion

The Organization and Diversity of Immunoglobulin κ and γ Genes

Discussion

Cell Surface Antigens and Cell Surface Proteins

Discussion

The Role of Products of the Histocompatibility Gene Complex in Immune Responses

Discussion

The Role of Thymosin and the Endocrine Thymus on the Ontogenesis and Function of T-Cells

Discussion

Immunoregulation by T Cells

Discussion

Control of Growth of Mammalian Cells

Discussion

Restricted Clonal Responses: A Tool in Understanding Antibody Specificity

Discussion

Poster Session: Communications

Repetitive Hinge Region Sequences in a γ3 Heavy Chain Disease Protein-Isolation of an 11,000 Dalton Fragment

Structural Characterization of a Mutant Human Lambda Immunoglobulin Type L-Chain

Heterogeneity of the C-Region of an IgGl Immunoglobulin: The Structure of γ-Heavy Chain Disease Protein Baz

Growth Factor for a Viral Transformed Cell From Rat Liver and Hemicorpus Perfusions

Lymphocyte Responses to Mitogens and Antigens in Agarose-Gel Cultures

Sterol Synthesis in Normal, Phytohemagglutinin-Stimulated, and Leukemic Mouse Lymphocytes

Can Protein Synthesis in Cultured Cells Be Regulated by Membrane- Mediated Events?

Alteration of Membrane Antigens by Trypsin

IgM Complex Receptors on T and B Lymphocytes

B and T Lymphocytes in Dysgammaglobulinemia

The Role of Thymic Extract in Transfer of Delayed Hypersensitivity (D.H.S.) and Immunostimulation

Growth Properties and Alloantigenic Expression of Murine Lymphoblastic Cell Lines Grown in Suspension Culture

Regulation of Ab Activity of Rabbit (Rab) Ig+Lymphocytes (LC) by Products of Rab Ig⁻LC

Evidence for the Genetic Control of Antigenic Modulation

The Response of Congenitally Athymic (NUDE) Mice to Infection with Mycobacterium bovis (Strain BCG)

Nonspecific Stimulators of the Immune System