Molecular and Cellular Mechanisms of Neuronal Plasticity in Normal Aging and Alzheimer's Disease, Volume 86

1st Edition

Editors: P.D. Coleman G.A. Higgins C.H. Phelps
Hardcover ISBN: 9780444811219
eBook ISBN: 9780080862118
Imprint: Elsevier Science
Published Date: 14th December 1990


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Table of Contents

List of contributors. Preface. Section I. Introductory Overview. Neural plasticity in aging and Alzheimer's disease: Some selected comments (C.H. Phelps). Section II. Cell Death. Glucocorticoids, hippocampal damage and the glutamatergic synapse (R.M. Saplosky). Hormones and programmed cell death: Insights from invertebrate studies (J.W. Truman, S.E. Fahrbach and K. Kimura). Excitotoxin-mediated neuron death in young and old age (J.W. Olney). Section III. Plasticity in Normal and Aging Systems and in AD. Plasticity of excitatory amino acid receptors: Implications for aging and Alzheimer's disease (C.W. Cotman, J.W. Geddes, J. Ulas and T. Klein). Neurono-glial interactions and neural plasticity (G. Moonen, B. Rogister, P. Leprince, J.-P. Rigo, P. Delrée, P.P. Lefèbvre and J. Schoenen). Neuronal plasticity in normal aging and deficient plasticity in Alzheimer's disease: A proposed intercellular signal cascade (P.D. Coleman, K.E. Rogers and D.G. Flood). Effects of aging on the dynamics of information processing and synaptic weight changes in the mammalian hippocampus (C.A. Barnes). Synaptic plasticity and behavioral modifications in the marine mollusk Aplysia (V.F. Castellucci and S. Schacher). Integration by the neuronal growth cone: A continuum from neuroplasticity to neuropathology (S.B. Kater, P.B. Guthrie and L.R. Mills). Intracortical processes regulating the integration of sensory information (F.F. Ebner and M.A. Armstrong-James). Section IV. Intercellular Mechanisms: Growth Factors and Their Receptors. Selective and non-selective trophic actions on central cholinergic and dopaminergic neurons in vitro (F. Hefti, B. Knusel and P.P. Michel). Neurotrophic factors in the CNS: Biosynthetic processing and functional responses (R.A. Bradshaw, J.G. Altin, M. Blaber, K.P. Cavanaugh, D.D. Eveleth, H.I. Kornblum, F.M. Leslie and S. Raffioni). S100-beta as a neurotrophic


Neuroscientists and researchers in Alzheimer's disease will find this book essential reading.


© Elsevier Science 1990
Elsevier Science
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About the Editors

P.D. Coleman Editor

G.A. Higgins Editor

C.H. Phelps Editor