Molecular and Cellular Aspects of Muscle Function - 1st Edition - ISBN: 9780080268170, 9781483280707

Molecular and Cellular Aspects of Muscle Function

1st Edition

Proceedings of the 28th International Congress of Physiological Sciences Budapest 1980, (including the proceedings of the satellite symposium on Membrane Control of Skeletal Muscle Function)

Editors: E. Varga A. Kövér T. Kovács
eBook ISBN: 9781483280707
Imprint: Pergamon
Published Date: 1st January 1981
Page Count: 454
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Description

Advances in Physiological Sciences, Volume 5: Molecular and Cellular Aspects of Muscle Function covers the proceedings of the 28th International Congress of Physiological Sciences, held in Budapest in 1980 (including the proceedings of the satellite symposium on Membrane Control of Skeletal Muscle Function). The book focuses on the molecular and cellular facets of skeletal muscle function.

The selection first offers information on the mechanical properties of cross-bridges and their relation to muscle contraction; molecular basis of functional specialization in muscle as induced by innervation; and electrical properties of crustacean muscle membranes. The text then ponders on contractile protein isoforms in developing muscle; effect of age and exercise on minced gastrocnemius muscle regeneration; and contractile proteins of rat gastrocnemius during its regeneration after mincing.

The publication examines the behavior of myosin projections in frog striated muscle during isometric contraction; energetics of contracting muscle and its relation to crossbridge mechanisms; and time course of chemical change and energy production during contraction of frog skeletal muscle. The physiological analysis of human myopathy and adaptation in normal and diseased muscle are also discussed.

The selection is a vital source of data for readers interested in the cellular and molecular aspects of muscle function.

Table of Contents


Foreword

Preface

The Mechanical Properties of Cross-Bridges and their Relation to Muscle Contraction

The Molecular Basis of Functional Specialization in Muscle as Induced by the Innervation

Electrical Properties of Crustacean Muscle Membranes

Calcium Exchange and Compartmentalization

Ca2+ Compartments in Vascular Smooth Muscle

Concluding Remarks on Calcium Exchange and Compartmentalization

Molecular and Functional Aspects of Muscle Differentiation

Contractile Protein Isoforms in Developing Muscle: The Nature of the Myosin Isozymes

The Effect of Age and Exercise on Minced Gastrocnemius Muscle Regeneration

The Contractile Proteins of Rat Gastrocnemius During its Regeneration After Mincing

The Role of Serum Proteins in the Differentiation of Skeletal Muscle Tissue in Vitro

Concluding Remarks on Molecular and Functional Aspects of Muscle Differentiation

Smooth Muscle

Mediators and Mechanisms of Activation of Contraction in Smooth Muscle

The Transport Mechanisms by which Contraction Activating Extracellular Ca2+ Ions Enter Smooth Muscle Cells (Introductory Remarks)

The Mechanisms of Action of Muscarinic Agonists on the Guinea-Pig Taenia Coli

The Contribution of Calcium to the Alpha-Action of Catecholamines on the Guinea-Pig Taenia Coli

Action of Apamin on Nerve-Muscle Transmission and the Effects of ATP and Noradrenaline in Smooth Muscles

On the Mechanisms Underlying the Relaxation of the Lower Esophageal and Ileocecal Sphincters in the Case of Increased K+

Relaxation of Tetanized Tracheal Smooth Muscle

Concluding Remarks on Smooth Muscle

Cross Bridge Mechanism and Energetics

Behaviour of Myosin Projections in Frog Striated Muscle During Isometric Contraction

The Energetics of Contracting Muscle and its Relation to Crossbridge Mechanisms

Energy Balance-Sheet in Isometric Tetani at 0°C

Time Course of Chemical Change and Energy Production During Contraction of Frog Skeletal Muscle

Heat Capacity Changes in Calcium and Magnesium Binding to Troponin

Data to the Problem of Unexplained Energy Production

Concluding Remarks on Cross-Bridge Mechanism and Energetics

Physiological Studies on Muscle Diseases

Physiological Analysis of Human Myopathy

Adaptation in Normal and Diseased Muscle

The Pathophysiology of Regenerating Skeletal Muscle

Physiological Studies on Myotonia

Contractile and Chemosensitive Properties of Diseased Muscle

"Leaky" Membrane Causes Weakness in Dystrophic Soleus Fibers

Neutral Amino Acid Transport into Skeletal Muscle

The Effects of Glucocorticoids on the Growth and Protein Turnover of Six Striated Muscles of the Rat

Effects of Glucocorticoids on Muscle Growth in Young Rats

Concluding Remarks on Physiological Studies on Muscle Diseases

Membrane Control of Skeletal Muscle Function

Satellite Symposium Debrecen

"Going Through the Usual Channels"

Cevadine Induced Changes of Na-Channels in Muscle Membrane

Inward Rectification in Skeletal Muscle Fibers

The Increase in Potassium Conductance in Metabolically Poisoned Skeletal Muscle Fibers

Chloride Conductance in Slow and Fast Mammalian Skeletal Muscle Fibers

Calcium Current in Twitch Muscle Fibers of the Frog

Ryanodine and the Calcium Channel in Crab Muscle Fibers

Three-Dimensional Structure of the T-System of Skeletal Muscle Cells

Ca++ Channels in Muscle Membrane: The Decline of Calcium Current Under Maintained Depolarization

Asymmetrical Charge Movement in Normal and Glycerol-Treated Toad Sartorius Fibers

The Role of Ion Movements in the Control of Metabolism in Skeletal Muscle

Effect of Caffeine on Mechanical Activation in Cut Skeletal Muscle Fibers

Does Indodicarbocyanine Fluorescence Reflect Membrane Potential of the Sarcoplasmic Reticulum in Skeletal Muscle?

Birefringence Signal and Latency Relaxation in Frog Skeletal Muscle Fibers

The Role of External Ca2+ in Excitation-Contraction Coupling

Surface and Tubular Membrane Sodium Currents in Frog Twitch Muscle Fibre; Implication in Excitation Contraction Coupling

A Sodium-Induced Calcium Release Mechanism on Frog Muscle Fibers; its Possible Role in the ECC Mechanism

Transient Kinetics for Ca Uptake by Fragmented Sarcoplasmic Reticulum from Bullfrog Skeletal Muscle with Reference to the Rate of Relaxation of Living Muscle

Index

Details

No. of pages:
454
Language:
English
Copyright:
© Pergamon 1981
Published:
Imprint:
Pergamon
eBook ISBN:
9781483280707

About the Editor

E. Varga

A. Kövér

T. Kovács