Molecular Advancements in Tropical Diseases Drug Discovery

Molecular Advancements in Tropical Diseases Drug Discovery

1st Edition - May 12, 2020

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  • Editors: Gauri Misra, Vijay Srivastava
  • eBook ISBN: 9780128213971
  • Paperback ISBN: 9780128212028

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Description

Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas.

Key Features

  • Updates knowledge about tropical diseases with recent advancements in the field
  • Presents an overview of new research covering detection, infection, epidemiology and risk factors of the most common tropical diseases using bioinformatics tools
  • Encompasses a detailed description of developments in drug discovery, new drugs and their molecular mechanisms of action

Readership

Bioinformaticians, graduate students, researchers on tropical diseases. Pharmacologists, molecular scientists

Table of Contents

  • Chapter 1. Amoebiasis   
    1.1 Introduction
    1.2 Detection of Infection
    1.3 Epidemiology and Risk Factors
    1.4 Approaches for Disease Control and Elimination
    1.5 Next-generation vaccines, drugs, and diagnostics
    1.6 New pathways as drug targets for disease intervention
    1.7 Concluding Remarks

    Chapter 2. Leishmaniasis 
    2.1 Introduction
    2.2 Detection of Infection
    2.3 Epidemiology and Risk Factors
    2.4 Approaches for Disease Control and Elimination
    2.5 Next-generation vaccines, drugs, and diagnostics
    2.6 New pathways as drug targets for disease intervention 
    2.7 Concluding Remarks

    Chapter 3. Tuberculosis 
    3.1 Introduction
    3.2 Detection of Infection
    3.3 Epidemiology and Risk Factors
    3.4 Approaches for Disease Control and Elimination
    3.5 Next-generation vaccines, drugs, and diagnostics
    3.6 New pathways as drug targets for disease intervention 
    3.7 Concluding Remarks

    Chapter 4. Lymphatic filariasis 
    4.1 Introduction
    4.2 Detection of Infection
    4.3 Epidemiology and Risk Factors
    4.4 Approaches for Disease Control and Elimination
    4.5 Next-generation vaccines, drugs, and diagnostics
    4.6 New pathways as drug targets for disease intervention 
    4.7 Concluding Remarks
     
    Chapter 5. Malaria  
    5.1Introduction
    5.2 Detection of Infection
    5.3 Epidemiology and Risk Factors
    5.4 Approaches for Disease Control and Elimination
    5.5 Next-generation vaccines, drugs, and diagnostics
    5.6 New pathways as drug targets for disease intervention 
    5.7 Concluding Remarks
     
    Chapter 6. Sleeping Sickness 
    6.1Introduction
    6.2 Detection of Infection
    6.3 Epidemiology and Risk Factors
    6.4 Approaches for Disease Control and Elimination
    6.5 Next-generation vaccines, drugs, and diagnostics
    6.6 New pathways as drug targets for disease intervention 
    6.7 Concluding Remarks

     

Product details

  • No. of pages: 154
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: May 12, 2020
  • Imprint: Academic Press
  • eBook ISBN: 9780128213971
  • Paperback ISBN: 9780128212028

About the Editors

Gauri Misra

Gauri Misra, PhD, has a research focus in the field of cancer biology and Malaria directed toward drug discovery, armored with an experience in Structural Biology, Biophysics and Bioinformatics. She has an outstanding academic background and experience of more than 10 years in the field of teaching and research, adorned by various prestigious awards and honors at different stages of her career with a strong desire of transferring her repertoire of knowledge to the upcoming generations. Her PhD thesis was awarded with Eli Lilly Asia Outstanding Thesis Award (first prize) in 2009. She has received “state of the art” International exposure while working as a postdoctoral researcher at CHUL Research Centre, Canada and visiting scientist at ISPC, Weizmann Institute of Science, Rehovot, Israel in 2014 along with few other countries. She serves as a reviewer for various renowned international journals and is often invited for speaking engagements about her research. To date, she has authored 17 research articles, 4 international books, and 6 book chapters. The ongoing research project in her laboratory focuses on evaluating the potential of new lead compounds against breast cancer.

Affiliations and Expertise

Scientist Grade-II, National Institute of Biologicals, (Autonomous Institute under Ministry of Health and Family Welfare), Government of India, Noida, Uttar Pradesh, India

Vijay Srivastava

Dr. Vijay Kumar Srivastava is an Assistant Professor in the Department of Biotechnology at the Amity Institute of Biotechnology in Jaipur, India. Dr. Srivastava has extensive research experience in pathogen biology working across Leishmania donovani, Mycobacterium tuberculosis and Entamoeba histolytica. He did his postdoctoral studies at the Indian Institute of Science Education and Research in Bhopal, India. He has published 22 research articles in journals of high repute, as well as two book chapters through Springer Nature and Elsevier. He has expertise in the field of Molecular Biology and Structural Biology with interdisciplinary expertise in Bioinformatics. Recently he has completed a DST-SERB project on Entamoeba histolytica as a PI/coordinator and was awarded an international travel grant from DST-India. His research primarily focuses on understanding the structure-function relationships of biologically significant soluble proteins.

Affiliations and Expertise

Assistant Professor, Amity Institute of Biotechnology, Amity University, Jaipur, Rajasthan, India

Ratings and Reviews

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  • Ajay S. Mon May 25 2020

    Simply the best

    Well written and easy to follow yet detailed enough to give a complete understanding of development in area of drug discovery. This book is a wonderful addition to books on drug discovery. Whether he/she is a academician or researcher, this book will be a valuable addition to his/her personal library.

  • Richa S. Mon May 25 2020

    Highly recommendable

    This book is extremely helpful for biomedical scientists, cellular and molecular biologist, students. In recent times we have seen the importance of drug discovery, so book like this is a boon for the millennials. It covers the topic well keeping all the minute information in consideration.

  • Richa S. Sat May 23 2020

    Excellent coverage

    This book is a great addition and is a valuable resource for biomedical scientist , cellular and molecular biologist and students. It has covered the tropical disease in great depth and will be quite helpful for the people engaged in this field. Highly recommended . In these days when we know the importance of a drug discovery, books like this is a boon to humans..

  • Rasish V. Thu May 21 2020

    A Brilliant Book

    This book has depth knowledge related to the detection of infection, epidemiology, drugs against the various tropical diseases, new target sites for the drug discovery and multidrug resistance issues.

  • Ritam V. Thu May 21 2020

    Insightful piece of work.

    I feel the writers have comprehended the content in the most lucid and precise manner. Looking forward more to come in line of health and medicines genre! Keep up the good work. :')

  • Shravan Wed May 20 2020

    About the Author Vijay

    Vijay is one of the exemplary SMEs in this area. Loved the way he has compiled the contents...looking forward to complete it ASAP