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Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas.
- Updates knowledge about tropical diseases with recent advancements in the field
- Presents an overview of new research covering detection, infection, epidemiology and risk factors of the most common tropical diseases using bioinformatics tools
- Encompasses a detailed description of developments in drug discovery, new drugs and their molecular mechanisms of action
Bioinformaticians, graduate students, researchers on tropical diseases. Pharmacologists, molecular scientists
Chapter 1. Amoebiasis
1.2 Detection of Infection
1.3 Epidemiology and Risk Factors
1.4 Approaches for Disease Control and Elimination
1.5 Next-generation vaccines, drugs, and diagnostics
1.6 New pathways as drug targets for disease intervention
1.7 Concluding Remarks
Chapter 2. Leishmaniasis
2.2 Detection of Infection
2.3 Epidemiology and Risk Factors
2.4 Approaches for Disease Control and Elimination
2.5 Next-generation vaccines, drugs, and diagnostics
2.6 New pathways as drug targets for disease intervention
2.7 Concluding Remarks
Chapter 3. Tuberculosis
3.2 Detection of Infection
3.3 Epidemiology and Risk Factors
3.4 Approaches for Disease Control and Elimination
3.5 Next-generation vaccines, drugs, and diagnostics
3.6 New pathways as drug targets for disease intervention
3.7 Concluding Remarks
Chapter 4. Lymphatic filariasis
4.2 Detection of Infection
4.3 Epidemiology and Risk Factors
4.4 Approaches for Disease Control and Elimination
4.5 Next-generation vaccines, drugs, and diagnostics
4.6 New pathways as drug targets for disease intervention
4.7 Concluding Remarks
Chapter 5. Malaria
5.2 Detection of Infection
5.3 Epidemiology and Risk Factors
5.4 Approaches for Disease Control and Elimination
5.5 Next-generation vaccines, drugs, and diagnostics
5.6 New pathways as drug targets for disease intervention
5.7 Concluding Remarks
Chapter 6. Sleeping Sickness
6.2 Detection of Infection
6.3 Epidemiology and Risk Factors
6.4 Approaches for Disease Control and Elimination
6.5 Next-generation vaccines, drugs, and diagnostics
6.6 New pathways as drug targets for disease intervention
6.7 Concluding Remarks
- No. of pages:
- © Academic Press 2020
- 13th May 2020
- Academic Press
- Paperback ISBN:
- eBook ISBN:
Dr. Gauri Misra is a Senior Scientist working at the National Institute of Biologicals, Noida. She has contributed significantly towards both teaching and research after obtaining her PhD from Central Drug Research Institute, Lucknow. She was the recipient of the prestigious Eli-Lilly Asia Outstanding Thesis Award (first prize) in 2009 and various other awards and honors at different stages of her career. Her postdoctoral work at CHUL Research Centre, Canada, paved the way towards understanding the role of androgen receptors in the growth and proliferation of breast cancer cells using structural biology approaches. Dr. Misra serves as a reviewer for various renowned international journals and is often invited for speaking engagements about her research. To date, she has authored 17 research articles, 3 international books, and 6 book chapters. The ongoing research project in her laboratory focusses on evaluating the potential of new lead compounds against breast cancer.
Scientist Grade-II, National Institute of Biologicals, Noida, Uttar Pradesh, India
Dr. Vijay Kumar Srivastava is an Assistant Professor in the Department of Biotechnology at the Amity Institute of Biotechnology in Jaipur, India. Dr. Srivastava has extensive research experience in pathogen biology working across Leishmania donovani, Mycobacterium tuberculosis and Entamoeba histolytica. He did his postdoctoral studies at the Indian Institute of Science Education and Research in Bhopal, India. He has published 22 research articles in journals of high repute, as well as two book chapters through Springer Nature and Elsevier. He has expertise in the field of Molecular Biology and Structural Biology with interdisciplinary expertise in Bioinformatics. Recently he has completed a DST-SERB project on Entamoeba histolytica as a PI/coordinator and was awarded an international travel grant from DST-India. His research primarily focuses on understanding the structure-function relationships of biologically significant soluble proteins.
Assistant Professor, Amity Institute of Biotechnology, Amity University, Jaipur, Rajasthan, India
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