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Molecular Advancements in Tropical Diseases Drug Discovery - 1st Edition - ISBN: 9780128212028, 9780128213971

Molecular Advancements in Tropical Diseases Drug Discovery

1st Edition

Editors: Gauri Misra Vijay Srivastava
Paperback ISBN: 9780128212028
eBook ISBN: 9780128213971
Imprint: Academic Press
Published Date: 13th May 2020
Page Count: 154
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Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas.

Key Features

  • Updates knowledge about tropical diseases with recent advancements in the field
  • Presents an overview of new research covering detection, infection, epidemiology and risk factors of the most common tropical diseases using bioinformatics tools
  • Encompasses a detailed description of developments in drug discovery, new drugs and their molecular mechanisms of action


Bioinformaticians, graduate students, researchers on tropical diseases. Pharmacologists, molecular scientists

Table of Contents

Chapter 1. Amoebiasis   
1.1 Introduction
1.2 Detection of Infection
1.3 Epidemiology and Risk Factors
1.4 Approaches for Disease Control and Elimination
1.5 Next-generation vaccines, drugs, and diagnostics
1.6 New pathways as drug targets for disease intervention
1.7 Concluding Remarks

Chapter 2. Leishmaniasis 
2.1 Introduction
2.2 Detection of Infection
2.3 Epidemiology and Risk Factors
2.4 Approaches for Disease Control and Elimination
2.5 Next-generation vaccines, drugs, and diagnostics
2.6 New pathways as drug targets for disease intervention 
2.7 Concluding Remarks

Chapter 3. Tuberculosis 
3.1 Introduction
3.2 Detection of Infection
3.3 Epidemiology and Risk Factors
3.4 Approaches for Disease Control and Elimination
3.5 Next-generation vaccines, drugs, and diagnostics
3.6 New pathways as drug targets for disease intervention 
3.7 Concluding Remarks

Chapter 4. Lymphatic filariasis 
4.1 Introduction
4.2 Detection of Infection
4.3 Epidemiology and Risk Factors
4.4 Approaches for Disease Control and Elimination
4.5 Next-generation vaccines, drugs, and diagnostics
4.6 New pathways as drug targets for disease intervention 
4.7 Concluding Remarks
Chapter 5. Malaria  
5.2 Detection of Infection
5.3 Epidemiology and Risk Factors
5.4 Approaches for Disease Control and Elimination
5.5 Next-generation vaccines, drugs, and diagnostics
5.6 New pathways as drug targets for disease intervention 
5.7 Concluding Remarks
Chapter 6. Sleeping Sickness 
6.2 Detection of Infection
6.3 Epidemiology and Risk Factors
6.4 Approaches for Disease Control and Elimination
6.5 Next-generation vaccines, drugs, and diagnostics
6.6 New pathways as drug targets for disease intervention 
6.7 Concluding Remarks



No. of pages:
© Academic Press 2020
13th May 2020
Academic Press
Paperback ISBN:
eBook ISBN:

About the Editors

Gauri Misra

Gauri Misra, PhD, has an outstanding academic background and experience of 10 years in the field of teaching and research, honored by various prestigious awards and with a strong desire of transferring her repertoire of knowledge to the upcoming generations. Dr. Misra’s PhD thesis was awarded with Eli Lilly Asia Outstanding Thesis Award (first prize) in 2009. Her postdoctoral work at CHUL Research Centre, Canada, paved the way towards understanding the role of androgen receptors in the growth and proliferation of breast cancer cells using structural biology approaches. Dr. Misra serves as a reviewer for various renowned international journals and is often invited for speaking engagements about her research. To date, she has authored 17 research articles, 4 international books, and 6 book chapters. The ongoing research project in her laboratory focusses on evaluating the potential of new lead compounds against breast cancer.

Affiliations and Expertise

Scientist-II, National Institute of Biologicals, Noida, India

Vijay Srivastava

Dr. Vijay Kumar Srivastava is an Assistant Professor in the Department of Biotechnology at the Amity Institute of Biotechnology in Jaipur, India. Dr. Srivastava has extensive research experience in pathogen biology working across Leishmania donovani, Mycobacterium tuberculosis and Entamoeba histolytica. He did his postdoctoral studies at the Indian Institute of Science Education and Research in Bhopal, India. He has published 22 research articles in journals of high repute, as well as two book chapters through Springer Nature and Elsevier. He has expertise in the field of Molecular Biology and Structural Biology with interdisciplinary expertise in Bioinformatics. Recently he has completed a DST-SERB project on Entamoeba histolytica as a PI/coordinator and was awarded an international travel grant from DST-India. His research primarily focuses on understanding the structure-function relationships of biologically significant soluble proteins.

Affiliations and Expertise

Assistant Professor, Amity Institute of Biotechnology, Amity University, Jaipur, Rajasthan, India

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