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Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas.
- Updates knowledge about tropical diseases with recent advancements in the field
- Presents an overview of new research covering detection, infection, epidemiology and risk factors of the most common tropical diseases using bioinformatics tools
- Encompasses a detailed description of developments in drug discovery, new drugs and their molecular mechanisms of action
Bioinformaticians, graduate students, researchers on tropical diseases. Pharmacologists, molecular scientists
Chapter 1. Amoebiasis
1.2 Detection of Infection
1.3 Epidemiology and Risk Factors
1.4 Approaches for Disease Control and Elimination
1.5 Next-generation vaccines, drugs, and diagnostics
1.6 New pathways as drug targets for disease intervention
1.7 Concluding Remarks
Chapter 2. Leishmaniasis
2.2 Detection of Infection
2.3 Epidemiology and Risk Factors
2.4 Approaches for Disease Control and Elimination
2.5 Next-generation vaccines, drugs, and diagnostics
2.6 New pathways as drug targets for disease intervention
2.7 Concluding Remarks
Chapter 3. Tuberculosis
3.2 Detection of Infection
3.3 Epidemiology and Risk Factors
3.4 Approaches for Disease Control and Elimination
3.5 Next-generation vaccines, drugs, and diagnostics
3.6 New pathways as drug targets for disease intervention
3.7 Concluding Remarks
Chapter 4. Lymphatic filariasis
4.2 Detection of Infection
4.3 Epidemiology and Risk Factors
4.4 Approaches for Disease Control and Elimination
4.5 Next-generation vaccines, drugs, and diagnostics
4.6 New pathways as drug targets for disease intervention
4.7 Concluding Remarks
Chapter 5. Malaria
5.2 Detection of Infection
5.3 Epidemiology and Risk Factors
5.4 Approaches for Disease Control and Elimination
5.5 Next-generation vaccines, drugs, and diagnostics
5.6 New pathways as drug targets for disease intervention
5.7 Concluding Remarks
Chapter 6. Sleeping Sickness
6.2 Detection of Infection
6.3 Epidemiology and Risk Factors
6.4 Approaches for Disease Control and Elimination
6.5 Next-generation vaccines, drugs, and diagnostics
6.6 New pathways as drug targets for disease intervention
6.7 Concluding Remarks
- No. of pages:
- © Academic Press 2020
- 12th May 2020
- Academic Press
- eBook ISBN:
- Paperback ISBN:
Gauri Misra, PhD, has a research focus in the field of cancer biology and Malaria directed toward drug discovery, armored with an experience in Structural Biology, Biophysics and Bioinformatics. She has an outstanding academic background and experience of more than 10 years in the field of teaching and research, adorned by various prestigious awards and honors at different stages of her career with a strong desire of transferring her repertoire of knowledge to the upcoming generations. Her PhD thesis was awarded with Eli Lilly Asia Outstanding Thesis Award (first prize) in 2009. She has received “state of the art” International exposure while working as a postdoctoral researcher at CHUL Research Centre, Canada and visiting scientist at ISPC, Weizmann Institute of Science, Rehovot, Israel in 2014 along with few other countries. She serves as a reviewer for various renowned international journals and is often invited for speaking engagements about her research. To date, she has authored 17 research articles, 4 international books, and 6 book chapters. The ongoing research project in her laboratory focuses on evaluating the potential of new lead compounds against breast cancer.
Scientist Grade-II, National Institute of Biologicals, (Autonomous Institute under Ministry of Health and Family Welfare), Government of India, Noida, Uttar Pradesh, India
Dr. Vijay Kumar Srivastava is an Assistant Professor in the Department of Biotechnology at the Amity Institute of Biotechnology in Jaipur, India. Dr. Srivastava has extensive research experience in pathogen biology working across Leishmania donovani, Mycobacterium tuberculosis and Entamoeba histolytica. He did his postdoctoral studies at the Indian Institute of Science Education and Research in Bhopal, India. He has published 22 research articles in journals of high repute, as well as two book chapters through Springer Nature and Elsevier. He has expertise in the field of Molecular Biology and Structural Biology with interdisciplinary expertise in Bioinformatics. Recently he has completed a DST-SERB project on Entamoeba histolytica as a PI/coordinator and was awarded an international travel grant from DST-India. His research primarily focuses on understanding the structure-function relationships of biologically significant soluble proteins.
Assistant Professor, Amity Institute of Biotechnology, Amity University, Jaipur, Rajasthan, India
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