Mitochondrial Function, Part B - 1st Edition - ISBN: 9780123746221, 9780080923505

Mitochondrial Function, Part B, Volume 457

1st Edition

Mitochondrial Protein Kinases, Protein Phosphatases and Mitochondrial Diseases

Serial Volume Editors: William Allison Anne Murphy
Hardcover ISBN: 9780123746221
eBook ISBN: 9780080923505
Imprint: Academic Press
Published Date: 15th May 2009
Page Count: 450
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Table of Contents

Defining the Mitochondrial Proteome

  1. Method to define the mammalian mitochondrial proteome; V. Mootha
  2. Proteome Characterization of Mouse Brain Mitochondria Using Electrospray Ionization Tandem Mass Spectrometry; X.Fang and C. S. Lee
  3. Method to analyze tissue heterogeneity of the mammalian mitochondrial proteome; R. S. Balaban
  4. Predicting proteomes of mitochondria and related organelles from genomic and expressed sequence tag data; D. Gaston, A. Tsausis and A. Roger
  5. MitoP2: the mitochondrial proteome database; H. Prokisch

Post-Translational Modifications of Mitochondrial Proteins

  1. Reversible protein acetylation in mitochondria; E. Verdin 7.Post-translational modifications of rat liver mitochondria outer membrane proteins' C. L. Hoppel 8.Characterization of a novel ser/thr protein phosphatase in mitochondria; Y. Wang
  2. R. Rizzuto 10.Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins; G. Pocsfalvi
  3. Isolation of Regulatory-competent, Phosphorylated Cytochrome c and Cytochrome c Oxidase; M. Hüttemann
  4. Identification of tyrosine phosphorylated proteins by Src kinases in rat brain; M. Salvi
  5. Detection of a mitochondrial kinase complex that mediates an ERK-dependent phosphorylation of mitochondrial protein in steroid biosynthesis; E. J. Podestá
  6. Dual specific phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane; J. Rardin & J. E. Dixon 15.M. A. Kostiuk and B. O. Keller: “Isolation and identification of palmitoylated proteins in mitochondria using a chemical biology approach; L. G. Berthiaume

Mitochondrial Dynamics 16.Mitochondrial fusion and movement using photoactivatable GFP; O. Shirihai

  1. Regulation of mitochondrial fission and fusion by kinase and phosphatase activities. no title yet; S. Strack
  2. Mitochondrial movement and synaptic function in Drosophila; T. L. Schwarz
  3. The use of yeast and a novel biosensor to study mitochondrial ion transport, swelling, and mitophagy; R. J. Scheweyen
    20.Complete Exchange of mtDNA’s between Mouse Cells for Testing the Effects of mtDNA on Tumor Phenotypes; J. Hayashi

Mitochondrial Function in Pancreatic Beta Cells

  1. Coupling efficiency INS-1E cells; M. D. Brand and C. Affourtit
  2. Methods in the study of substrate-specific differences on mitochondrial function mediating insulin secretion from pancreatic beta cells; B. E. Corkey
  3. Knocking down of UCP 2 in animal models of obesity; L. A.Velloso 24.Roles of the cytosolic and mitochondrial forms of the malic enzyme on insulin secretion; G. W. Cline
  4. Altered regulation of the PINK1 locus as a link between type 2 diabetes and neurodegeneration; J. A. Timmons
  5. Insulin secretion from pancreatic beta cells is affected deletion of the nicotinamide nucleotide transhydrogenase; R. D. Cox
  6. Determination of oxidative capacity and mitochondrial function in insulin resistance and type 2 diabetes; G. Shulman et al 28.Mitochondrial ATP production rate; K. S. Nair

Description

Defining the Mitochondrial Proteome

  1. Method to define the mammalian mitochondrial proteome; V. Mootha
  2. Proteome Characterization of Mouse Brain Mitochondria Using Electrospray Ionization Tandem Mass Spectrometry; X.Fang and C. S. Lee
  3. Method to analyze tissue heterogeneity of the mammalian mitochondrial proteome; R. S. Balaban
  4. Predicting proteomes of mitochondria and related organelles from genomic and expressed sequence tag data; D. Gaston, A. Tsausis and A. Roger
  5. MitoP2: the mitochondrial proteome database; H. Prokisch

Post-Translational Modifications of Mitochondrial Proteins

  1. Reversible protein acetylation in mitochondria; E. Verdin 7.Post-translational modifications of rat liver mitochondria outer membrane proteins' C. L. Hoppel 8.Characterization of a novel ser/thr protein phosphatase in mitochondria; Y. Wang
  2. R. Rizzuto 10.Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins; G. Pocsfalvi
  3. Isolation of Regulatory-competent, Phosphorylated Cytochrome c and Cytochrome c Oxidase; M. Hüttemann
  4. Identification of tyrosine phosphorylated proteins by Src kinases in rat brain; M. Salvi
  5. Detection of a mitochondrial kinase complex that mediates an ERK-dependent phosphorylation of mitochondrial protein in steroid biosynthesis; E. J. Podestá
  6. Dual specific phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane; J. Rardin & J. E. Dixon 15.M. A. Kostiuk and B. O. Keller: “Isolation and identification of palmitoylated proteins in mitochondria using a chemical biology approach; L. G. Berthiaume

Mitochondrial Dynamics 16.Mitochondrial fusion and movement using photoactivatable GFP; O. Shirihai

  1. Regulation of mitochondrial fission and fusion by kinase and phosphatase activities. no title yet; S. Strack
  2. Mitochondrial movement and synaptic function in Drosophila; T. L. Schwarz
  3. The use of yeast and a novel biosensor to study mitochondrial ion transport, swelling, and mitophagy; R. J. Scheweyen
    20.Complete Exchange of mtDNA’s between Mouse Cells for Testing the Effects of mtDNA on Tumor Phenotypes; J. Hayashi

Mitochondrial Function in Pancreatic Beta Cells

  1. Coupling efficiency INS-1E cells; M. D. Brand and C. Affourtit
  2. Methods in the study of substrate-specific differences on mitochondrial function mediating insulin secretion from pancreatic beta cells; B. E. Corkey
  3. Knocking down of UCP 2 in animal models of obesity; L. A.Velloso 24.Roles of the cytosolic and mitochondrial forms of the malic enzyme on insulin secretion; G. W. Cline
  4. Altered regulation of the PINK1 locus as a link between type 2 diabetes and neurodegeneration; J. A. Timmons
  5. Insulin secretion from pancreatic beta cells is affected deletion of the nicotinamide nucleotide transhydrogenase; R. D. Cox
  6. Determination of oxidative capacity and mitochondrial function in insulin resistance and type 2 diabetes; G. Shulman et al 28.Mitochondrial ATP production rate; K. S. Nair

Key Features

New methods focusing on the examination of normal and abnormal mitochondrial function are presented in an easy-to-follow format by the researchers who developed them

Along with a companion volume covering topics including mitochondrial electron transport chain complexes and reactive oxygen species, provides a comprehensive overview of modern techniques in the study of mitochondrial malfunction

Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods

Readership

Researchers, professors, and students of biochemistry, molecular biology and cell biology


Details

No. of pages:
450
Language:
English
Copyright:
© Academic Press 2009
Published:
Imprint:
Academic Press
eBook ISBN:
9780080923505
Hardcover ISBN:
9780123746221

About the Serial Volume Editors

William Allison Serial Volume Editor

Anne Murphy Serial Volume Editor