Microfluidics in Cell Biology Part B - 1st Edition - ISBN: 9780128142820

Microfluidics in Cell Biology Part B, Volume 147

1st Edition

Serial Volume Editors: Matthieu Piel Junsang Doh Daniel Fletcher
Hardcover ISBN: 9780128142820
Imprint: Academic Press
Published Date: 1st September 2018
Page Count: 362
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Table of Contents

Section 1 - Microfluidics for micro-organisms
1. Temperature control and drug delivery for cell division cycle control in fission yeast
Damien Coudreuse
2. H2O2 stress response in budding yeast
Gilles Charvin
3. Antibiotic resistance in bacteria
Bob Austin and Julia Bos
4. Metabolism in bacteria
Andrew Griffiths and Philippe Nghe
5. Fluidized beds for bacterial sorting and amplification
Stephanie Descroix and Jean-Louis Viovy

Section 2 - Microfluidics for cell culture and cell sorting of mammalian cells
6. Hydrogel microwells
Samy Gobaa
7. Cell sorting with conical filters
Yong Chen and Olivier Shi
8. Directed neuronal cell culture
Catherine Villard and Jean-Louis Viovy

Section 3 - Microfluidics for cell migration
9. Immune cells migration in complexe environments
Michael Sixt
10. Neutrophiles migration in health and disease
Daniel Irimia
11. Cell guidance by physical cues
Daniel Riveline
12. Stable gradients in gels of extracellular matrix for cancer cell migration
Danijela Vignjevic

Section 4 - Microfluidics for cell mechanics
13. Size based cell sorting and single cell mechanobiology
Chwee Teck Lim
14. High throughput measure of single cell deformability/stiffness
Jochen Guck
15. Host-microbe interactions
John McKinney
16. Cell confinement and intracellular crowding
Liam Holt, Morgan Delarue and Oskar Hallatschek

Section 5 - Microfluidics for Single cell analytics
17. Quantification of single cell secretion
Andrew Griffiths
18. Mechanical cell disruption
Wenhui Wang


Microfluidics in Cell Biology Part B: Microfluidics in Single Cells, Volume 147, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are three sections on microfluidics in various single cell models, including microfludics in micro-organisms, microfluidics for cell culture and cell sorting of mammalian cells, and microfluidics for cell migration.

Specific sections in this latest release include Temperature control and drug delivery for cell division cycle control in fission yeast H2O2 stress response in budding yeast, Antibiotic resistance in bacteria, Metabolism in bacteria, Fluidized beds for bacterial sorting and amplification, Microfluidics for cell culture and cell sorting of mammalian cells, Hydrogel microwells, Immune cells migration in complex environments, Neutrophiles migration in health and disease, Cell guidance by physical cues, Stable gradients in gels of extracellular matrix for cancer cell migration, and more.

Key Features

  • Contains contributions from experts in the field from across the world
  • Covers a wide array of topics on both mitosis and meiosis
  • Includes relevant, analysis based topics


Researchers and academics in the cell biology field


No. of pages:
© Academic Press 2018
Academic Press
Hardcover ISBN:

Ratings and Reviews

About the Serial Volume Editors

Matthieu Piel Serial Volume Editor

Dr. Piel is author of more than 60 publications. He holds three patents, and is a co-founder of the CYTOO Company. He is teaching at the Center for Interdisciplinary Research in Institut Cochin. He also teaches cell biology and biophysics in several master courses in Paris. He is one of the founder of Institut Pierre-Gilles de Gennes for Microfluidics. He has been invited to over 30 international meetings and gave over 40 seminars in the last 5 years. He was awaded the Bronze medal of CNRS in 2012.

Affiliations and Expertise

Systems Biology of Cell Division and Cell Polarity, Institut Curie, France

Junsang Doh Serial Volume Editor

Prof. Doh received his bachelor’s degree in Chemical Engineering from Seoul National University in 1999. He then moved to MIT for his graduate work with Prof. Darrell J. Irvine in the development of multi-component protein micropatterned surfaces for the study of the immunological synapses formed in T cells during activation. He received his PhD in 2006 in Chemical Engineering/Program in Polymer Science and Technology. As a postdoctoral researcher, Dr. Doh studied homotypic interactions among activating T cells in the laboratory of Max Krummel at UC San Francisco from 2006-2008. In 2008, he joined Pohang University of Science and Technology (POSTECH) with a joint appointment in Interdisciplinary Bioscience and Bioengineering (I-Bio) and Mechanical Engineering. Currently, Prof. Doh’s group develops engineering tools such as microfabrication/imaging/mechanics to study fundamental aspects of immune synapses and cell motility in the context of cancer immunotherapy.

Affiliations and Expertise

Associate Professor, Department of Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering (I-Bio), Pohang University of Science and Technology

Daniel Fletcher Serial Volume Editor

Dr. Fletcher and his team develops diagnostic technologies and studies mechanical regulation of membrane and cytoskeleton organization in the context of cell motility, signaling, and host-pathogen interactions. His lab specialize in development of optical microscopy, force microscopy, and microfluidic technologies to understand fundamental organizational principles through both in vitro reconstitution and live cell experiments. Recent work includes investigating the mechano-biochemistry of branched actin network assembly with force microscopy, studying membrane deformation by protein crowding and oligomerization with model membranes, and reconstituting spindle scaling in encapsulated cytoplasmic extracts. The long-term goal of his work is to understand and harness spatial organization for therapeutic applications in cancer and infectious diseases.

Affiliations and Expertise

Purnendu Chatterjee Chair in Engineering Biological Systems, Department of Bioengineering, UC Berkeley Faculty Scientist, Lawrence Berkeley National Laboratory Deputy Division Director, Physical Biosciences Division, Lawrence Berkeley National Laboratory