Microcompartmentation and Phase Separation in Cytoplasm

Microcompartmentation and Phase Separation in Cytoplasm

A Survey of Cell Biology

1st Edition - October 13, 1999

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  • Editor: Kwang Jeon
  • eBook ISBN: 9780080857312

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International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.This volume provides an overview of major cytoplasmic properties and events which including cytoarchitecture and the physical properties of cytoplasm, molecular compartmentation and gradients, channeling, sorting, and trafficking. It also addresses physicochemical events, both measured and anticipated, which attend solutions under conditions prevailing in cytoplasm: molecular crowding. It summarizes the current state of knowledge in the field and considers questions such as how molecules in cytoplasm interact.


Biochemists, cell biologists, molecular biologists, biophysicists, and physiologists.

Table of Contents

  • Physicochemical Properties of Aqueous Phase Systems and Partitioning Behavior of Biomaterials:
    V. Tolstoguzov, Compositions and Phase Diagrams for Aqueous Systems Based on Proteins and Polysaccharides.
    G. Johansson and H. Walter, Partitioning and Concentrating Biomaterials in Auqeous Phase Systems.
    G. Kopperschläger, Effects of Specific Binding Reactions on the Partitioning Behavior of Biomaterials.
    H. Cabezas, Properties of Interfaces and Transport Across Them.
    F. Tjerneld and H.-O. Johansson, Compartmentalization of Enzymes and Distribution of Products in Aqueous Two-Phase Systems.
    Physicochemical Properties of Cytoplasm:
    H.-O. Johansson, D.E. Brooks, and C.A. Haynes, Macromolecular Crowding and Its Consequences.
    J.I. Clark and J.M. Clark, Lens Cytoplasmic Phase Separation.
    K. Luby-Phelps, Cytoarchitecture and Physical Properties of Cytoplasm: Volume, Viscosity, Diffusion, Intracellular Surface Area.
    T.Y. Aw, Intracellular Compartmentation of Organelles and Gradients of Low Molecular Weight Species.
    J. Ovádi and P.A. Srere, Macromolecular Compartmentation and Channeling.
    K.D. Garlid, The State of Water in Biological Systems.
    L. Pagliaro, Mechanisms for Cytoplasmic Organization: An Overview.
    Cytoplasm and Phase Separation:
    D.E. Brooks, Can Cytoplasm Exist Without Undergoing Phase Separation?
    H. Walter, Consequences of Phase Separation in Cytoplasm.
    Chapter References.

Product details

  • No. of pages: 352
  • Language: English
  • Copyright: © Academic Press 1999
  • Published: October 13, 1999
  • Imprint: Academic Press
  • eBook ISBN: 9780080857312

About the Serial Editor

Kwang Jeon

Kwang Jeon
Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.

Affiliations and Expertise

University of Tennessee, Knoxville, TN, USA

About the Serial Volume Editors

Harry Walter

Affiliations and Expertise

Aqueous Phase Systems, Washington, D.C., U.S.A.

Donald Brooks

Affiliations and Expertise

University of British Columbia, Vancouver, Canada

Paul Srere

Affiliations and Expertise

Veterans Affairs Medical Center, Dallas, Texas, U.S.A.

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