Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications - 1st Edition - ISBN: 9780128152492

Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications

1st Edition

Editors: Joel Faintuch Salamao Faintuch
Paperback ISBN: 9780128152492
Imprint: Academic Press
Published Date: 1st February 2019
Page Count: 328
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Description

Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications, is the first book to simultaneously cover the microbiome and the metabolome, in relevant clinical conditions. In a pioneering fashion, it addresses not only the classic intestinal environment, but also oral, gastric, lung, skin, and vaginal microbiome, in line with the latest investigations. Nonbacterial microbiomes, such as fungi and viruses, are not overlooked, and also the plasma microbiome is briefly mentioned. Plasma, brain, placenta, tumor cells, and other "sterile" fluids and tissues, are increasingly recognized to potentially host a microbiome, albeit a limited one.

Emphasis was given to practical health-care applications, namely diagnosis, therapy, and disease prevention, not overlooking impact on foods, drugs and xenobiotics, to which the human organism is exposed. Information on the transcriptome, proteome and lipidome were conveyed whenever significant. The editors were fortunate to count on renowned collaborators from nearly all continents. This is truly an international effort, to bring the latest in the field to students and professionals alike.

Key Features

  • Comprehensive coverage of diagnosis, therapy, pharmacotherapy, and disease prevention in context of the microbiome and metabolome
  • Chapters focus on the proposed physiological or pathological conditions
  • Up-to-date useful references, for additional research and database access

Readership

Gastroenterology Researchers, gastroenterologists, general doctors, students, residents, nurses, microbiologists, food and nutrition scientists

Table of Contents

Block one – Tools, toolstations and models
1. Germ free animals
2. Gnotobiotic animals in cardiovascular disease
3. Viruses and Fungi
4. Gut Metabolome
5. Metabolome tools and information retrieval
6. In-vitro model of microbiome
7. Breath analysis

Block two – Background information
8. Infancy to elderly
9. The oral microbiome
10. Gastric microbiome
11. The Human Vaginal Microbiome
12. Bioactive molecules of the microbiome
13. Intestinal barrier and mucosal defense
14. The Crosstalk Between Bile Acids and Intestinal Microbiota

Block three – Established and experimental interventions
15. Probiotics in inflammatory bowel disease
16. Fecal transplantation
17. Effects of probiotics on improvement of metabolic factors in pregnant women: a meta-analysis of randomised placebo-controlled trials
18. Fecal transplantation Clostridium difficile
19. Phage therapy
20. Antibiotics
21. The myth and therapeutic potentials of postbiotics

Block four – Diagnostic and therapeutical applications
22. Diabetes
23. Obesity
24. Bariatric surgery
25. Hypertension
26. Functional digestive diseases
27. The microbiome and metabolome in nonalcoholic fatty liver disease
28. The Microbiome and metabolome in alcoholic liver disease
29. Neonatal sepsis
30. Septic elderly
31. The lung microbiome and metabolome in the diagnosis of pulmonary disease
32. HIV infection
33. Autoimmune diseases
34. Multiple sclerosis
35. Bone health
36. Kidney diseases
37. Dysbiosis in benign and malignant diseases of the exocrine pancreas
38. Cancer
39. The Microbiome in Graft versus host disease
40. Emotions

Block five - Applications for foods, drugs, and xenobiotics
41. Vegetarians
42. Metformin antiobesity
43. Smog and the intestinal microbiome

Block six - Challenges and promises for the future
44. New generation probiotics
45. Fecal transplantation in inflammatory bowel disease
46. The future of the microbiome and metabolome

Details

No. of pages:
328
Language:
English
Copyright:
© Academic Press 2019
Published:
Imprint:
Academic Press
Paperback ISBN:
9780128152492

About the Editor

Joel Faintuch

Joel Faintuch is a gastrointestinal surgeon, and former International Guest Fellow of the American College of Surgeons. He is Honorary Fellow of three Surgical Societies, and has served as Visiting Professor at the University of Maastricht. He was the pioneer of Parenteral and Enteral Nutrition in Brazil and South America, and a founding member of three medical societies. In the last years, his focus has been in the Intestinal Microbiome. Joel Faintuch is the author of over 250 articles in peer-reviewed journals, along with 10 books, three theses, and over 200 chapters in books, and other publications.

Affiliations and Expertise

Senior Professor, Department of Gastroenterology, Sao Paulo University Medical School, Sao Paulo, Brazil

Salamao Faintuch

Salomao Faintuch is the Clinical Director of Vascular and Interventional Radiology at Beth Israel Deaconess Medical Center and Harvard Medical School. He has authored more than 50 articles in peer-reviewed journals, along with 5 Society Guidelines and Standards of Practice and 3 textbooks. He is a Radiological Society of North America Research Scholar, serves in eight national society committees, and is member of the Editorial Board of three international journals.

Affiliations and Expertise

Clinical Director of Vascular and Interventional Radiology, Co-Director, Advanced Vascular Care Center, Assistant Professor of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Massachusetts, USA

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