Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications

Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications

1st Edition - January 3, 2019

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  • Editors: Joel Faintuch, Salamao Faintuch
  • eBook ISBN: 9780128152508
  • Paperback ISBN: 9780128152492

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Microbiome and Metabolome in Diagnosis, Therapy, and Other Strategic Applications is the first book to simultaneously cover the microbiome and the metabolome in relevant clinical conditions. In a pioneering fashion, it addresses not only the classic intestinal environment, but also the oral, gastric, lung, skin and vaginal microbiome that is in line with the latest investigations. Nonbacterial microbiomes, such as fungi and viruses are not overlooked, and the plasma microbiome is also discussed. As plasma, brain, placenta, tumor cells, and other sterile fluids and tissues, are increasingly recognized to potentially host a microbiome, albeit a limited one, this is a timely resource. The book's editors were fortunate to have the input of renowned collaborators from nearly all continents. This is truly an international effort that brings the latest in the field to students and professionals alike.

Key Features

  • Provides comprehensive coverage on diagnosis, therapy, pharmacotherapy and disease prevention in context of the microbiome and metabolome
  • Focuses on the proposed physiological or pathological conditions
  • Presents an up-to-date, useful reference


Gastroenterology Researchers, gastroenterologists, general doctors, students, residents, nurses, microbiologists, food and nutrition scientists

Table of Contents

  • Block I Tools, Toolstations and Models
    1. Germ-Free Animals as a Tool to Study Indigenous Microbiota
    2. Germ-Free Mouse Technology in Cardiovascular Research
    3. The Gut Microbiome Beyond the BacteriomedThe Neglected Role of Virome and Mycobiome in Health and Disease
    4. Techniques for Phenotyping the Gut Microbiota Metabolome
    5. Metabolomics Tools and Information Retrieval in Microbiome Hacking
    6. Laboratory Simulators of the Colon Microbiome
    7. Potential of Metabolomics to Breath Tests

    Block II Background Information
    8. Metabolome and Microbiome From Infancy to Elderly
    9. The Oral Microbiome
    10. The Gastric Microbiome in Benign and Malignant Diseases
    11. The Human Vaginal Microbiome
    12. Bioactive Molecules of the Human Microbiome: Skin, Respiratory Tract, Intestine
    13. Role of the Microbiome in Intestinal Barrier Function and Immune Defense
    14. The Cross Talk Between Bile Acids and Intestinal Microbiota: Focus on Metabolic Diseases and Bariatric Surgery

    Block III Established and Experimental Interventions
    15. Use of Probiotics in Inflammatory Bowel Disease
    16. Current Status of Fecal Microbiota Transplantation
    17. Effects of Probiotics on Improvement of Metabolic Factors in Pregnant Women: A Metaanalysis of Randomized Placebo-Controlled Trials
    18. Current Options for Fecal Transplantation in Clostridium difficile Infection
    19. Targeted Delivery of Bacteriophages to the Gastrointestinal Tract and Their Controlled Release: Unleashing the Therapeutic Potential of Phage Therapy
    20. The Unknown Effect of AntibioticInduced Dysbiosis on the Gut Microbiota
    21. The Myth and Therapeutic Potentials of Postbiotics

    Block IV Diagnostic and Therapeutical Applications
    22. The Microbiome and Metabolome in Metabolic Syndrome
    23. The Gut Microbiota as a Therapeutic Approach for Obesity
    24. The Gut Microbiome After Bariatric Surgery
    25. Gut Dysbiosis in Arterial Hypertension: A Candidate Therapeutic Target for Blood Pressure Management
    26. The Emerging Role of MicrobiomeeGuteBrain Axis in Functional Gastrointestinal Disorders
    27. The Microbiome and Metabolome in Nonalcoholic Fatty Liver Disease
    28. The Microbiome and Metabolome in Alcoholic Liver Disease
    29. The Microbiome, Metabolome, and Proteome in Preterm Neonatal Sepsis
    30. Gut Microbiome in the Elderly Hospitalized Patient: A Marker of Disease and Prognosis?
    31. The Lung Microbiome, Metabolome, and Breath Volatolome in the Diagnosis of Pulmonary Disease

Product details

  • No. of pages: 504
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: January 3, 2019
  • Imprint: Academic Press
  • eBook ISBN: 9780128152508
  • Paperback ISBN: 9780128152492

About the Editors

Joel Faintuch

Joel Faintuch is a gastrointestinal surgeon, and former International Guest Fellow of the American College of Surgeons. He is Honorary Fellow of three Surgical Societies, and has served as Visiting Professor at the University of Maastricht. He was the pioneer of Parenteral and Enteral Nutrition in Brazil and South America, and a founding member of three medical societies. In the last years, his focus has been in the Intestinal Microbiome. Joel Faintuch is the author of over 250 articles in peer-reviewed journals, along with 10 books, three theses, and over 200 chapters in books, and other publications.

Affiliations and Expertise

Senior Professor, Department of Gastroenterology, Sao Paulo University Medical School, Sao Paulo, Brazil

Salamao Faintuch

Salomao Faintuch is the Clinical Director of Vascular and Interventional Radiology at Beth Israel Deaconess Medical Center and Harvard Medical School. He has authored more than 50 articles in peer-reviewed journals, along with 5 Society Guidelines and Standards of Practice and 3 textbooks. He is a Radiological Society of North America Research Scholar, serves in eight national society committees, and is member of the Editorial Board of three international journals.

Affiliations and Expertise

Clinical Director of Vascular and Interventional Radiology, Co-Director, Advanced Vascular Care Center, Assistant Professor of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Massachusetts, USA

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