Microbiology for Surgical Infections - 1st Edition - ISBN: 9780124116290, 9780124116429

Microbiology for Surgical Infections

1st Edition

Diagnosis, Prognosis and Treatment

Editors: Kateryna Kon Mahendra Rai
Hardcover ISBN: 9780124116290
eBook ISBN: 9780124116429
Imprint: Academic Press
Published Date: 18th March 2014
Page Count: 324
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Microbiology for Surgical Infections: Diagnosis, Prognosis and Treatment explores current trends in etiology and antibiotic resistance of pathogens responsible for devastating and complex surgical infections. Clinicians and researchers report the most recent advances in diagnostic approaches to bacterial and non-bacterial surgical infections, including invasive fungal infections. Current guidelines for prophylaxis of community-acquired and nosocomial infections, complications in surgery, and improvement of diagnosis and treatment of these devastating surgical infections are also discussed.

The work gives specific attention to intra-abdominal and wound infections, as well as infections in cardiac surgery and neurosurgery. Taken together, these explorations inform the work of specialists in different surgical arenas, as well as those working in microbiology.

Microbiology for Surgical Infections provides a resource to those working to improve outcomes in this complicated arena by discussing prospects for future study and identifying targets for future research.

Key Features

  • Provides a multi-dimensional view of myriad topics pertinent to surgical infections, including questions of etiology, pathogenesis, host-microbial interactions, diagnosis, prognosis, treatment and prophylaxis
  • Delivers cutting-edge commentary from eminent surgeons, microbiologists, and infectious disease specialists, with global contributions from both the developed and developing worlds
  • Presents comprehensive research informed by the most recent technological and scientific advances in the field


academics and researchers in microbiology, infectious diseases and antibiotic resistance, medical students, clinicians, laboratory scientists, infection preventionists, public health specialists

Table of Contents

  • Preface
  • List of Contributors
  • Section I: Infection Control Measures for the Prevention of Surgical Infections
    • Chapter 1. Infection Control Measures for the Prevention of Surgical Site Infections
      • Consequences of Surgical Site Infections
      • Infection Control Measures Before the Start of the Surgical Procedure
      • Infection Control Measures During the Surgical Procedure
      • Infection Control Measures After the End of the Surgical Procedure
      • Adherence to Infection Control Recommendations
      • References
    • Chapter 2. Microbiological Assessment before Surgical Intervention
      • Introduction
      • Purpose of Microbiological Assessment
      • Patient Factors in Microbiological Assessment of a Surgical Patient
      • Organizational Factors in the Microbiological Assessment of a Surgical Patient (Table 2.2B)
      • Conclusions and Future Prospects
      • References
    • Chapter 3. Bacterial Adherence to Biomaterials Used in Surgical Procedures
      • Introduction
      • The Role of Bacterial Properties in Adherence
      • The Role of Biomaterial Properties
      • Prevention of Biomaterial Infection
      • Conclusions and Future Prospects
      • References
  • Section II: Intra-Abdominal Infections
    • Chapter 4. Multidrug-Resistant Bacteria in Pancreatic Surgery
      • Introduction
      • The Impact of Preoperative Biliary Drainage (Pbd) on Bile Bacteriology and Outcome
      • The Etiology of MDR Infections
      • MDR Microorganisms
      • Extended Spectrum β-Lactamase (ESBL) Producing Enterobacteriaceae
      • Treatment Options
      • Treatment Strategies – Recommendations for MDR Microorganisms – Taragona Strategy
      • Conclusions and Future Prospects
      • References
    • Chapter 5. Anastomotic Leakage after Colonic and Rectal Surgery: Operative and Conservative Management
      • Introduction
      • Definition of Anastomotic Leakage
      • Epidemiology
      • Risk Factors
      • Clinical Signs and Symptoms of Anastomotic Leakage
      • Diagnosis
      • Treatment and Prognosis
      • Conclusions and Future Prospects
      • References
    • Chapter 6. Acute Appendicitis: An Open Issue. Current Trends in Diagnostic and Therapeutic Options
      • Introduction
      • Clinical Signs and Symptoms
      • Diagnosis
      • Treatment
      • Conclusions and Future Prospects
      • References
    • Chapter 7. Assessment of Severity and Prognosis in Surgical Patients with Secondary Peritonitis
      • Introduction
      • The Progression of Severity Scores
      • Discussion
      • Conclusions
      • References
    • Chapter 8. Pathogenesis and Management of Dialysis Access Infections
      • Introduction
      • Dialysis Access
      • Epidemiology
      • Pathogenesis and Risk Factors
      • Clinical Manifestations, Diagnosis, Treatment And Prevention
      • Conclusions and Future Prospects
      • References
    • Chapter 9. Microbiological Diagnosis and Antimicrobial Therapy in Acute Pancreatitis
      • Introduction
      • Infected Pancreatic Necrosis (IPN)
      • Antimicrobial Therapy
      • Conclusion and Future Prospects
      • References
  • Section III: Cardiovascular Infections
    • Chapter 10. Infective Endocarditis
      • Introduction
      • Risk Factors
      • Infectious Agents
      • Culture Negative Endocarditis
      • Gross Pathology of Infective Endocarditis
      • Histopathology of Infective Endocarditis
      • Prosthetic Valve Endocarditis
      • Non-Infectious Endocarditis (Nonbacterial Thrombotic Endocarditis)
      • Clinical Presentation
      • Diagnosis
      • Management
      • Surgical Treatment
      • Conclusions and Future Prospects
      • References
  • Section IV: Skin and Soft Tissue Infections
    • Chapter 11. Natural Remedies for the Treatment of Wounds and Wound Infection
      • Introduction
      • Plant Essential Oils in the Treatment of Wounds and Wound Infection
      • Amphibian Skin Secretions in the Treatment of Wounds
      • Maggots in the Treatment of Wounds
      • Conclusions and Future Prospects
      • References
    • Chapter 12. Bioactive Molecules of Herbal Extracts with Anti-Infective and Wound Healing Properties
      • Introduction
      • Medicinal Plants with Wound Healing and Anti-Infective Properties
      • Conclusions and Future Prospects
      • References
    • Chapter 13. The Role of Honey and Propolis in the Treatment of Infected Wounds
      • Introduction
      • Phenolic and Flavonoid Compounds
      • Antimicrobial Activity in the Treatment of Infected Wounds and in Wounds Healing
      • Other Applications of Honey and Propolis in Human Health
      • Conclusions and Future Prospects
      • References
    • Chapter 14. Necrotizing Soft Tissue Infections
      • Introduction
      • Pathogenesis of NSTI
      • Diagnosis
      • Risk Factors
      • Pathogens of NSTI
      • Clostridial Necrotizing Infection
      • Streptococcal Necrotizing Infection
      • Staphylococcal Necrotizing Infection
      • Polymicrobial Necrotizing Infections
      • Other Pathogens
      • Conclusions and Future Prospects
      • References
    • Chapter 15. Significance of Surgical Intervention in the Management of Diabetic Foot Infections
      • Introduction
      • Definition of Diabetic Foot
      • Epidemiology
      • Pathogenesis of Diabetic Foot Ulcer
      • Classification of Diabetic Foot
      • Diagnosis of Diabetic Foot Infection
      • Microbiology of Diabetic Foot Infection
      • Management of Diabetic Foot Infection
      • Antibiotic Selection
      • Surgical Intervention
      • Conclusions and Future Prospects
      • Acknowledgment
      • References
  • Section V: Skeletal Infections
    • Chapter 16. Spinal Epidural Abscesses
      • Introduction
      • Epidemiology
      • Pathophysiology of Infection
      • Anatomical Considerations
      • Pathophysiology of Neurological Deficit
      • When Should Sea be Suspected?
      • Differential Diagnosis
      • Investigations
      • Microbiology
      • Clinical Management
      • Prognosis
      • Conclusion and Future Prospects
      • References
  • Section VI: Surgical Infections of Non-Bacterial Origin
    • Chapter 17. State of the Art in the Laboratory Methods for the Diagnosis of Invasive Fungal Diseases
      • Introduction
      • Traditional Microbiological Diagnosis
      • Alternative Methods for Diagnosis: Non-Culture Based Methods
      • Conclusion: Proposed Clinical Uses and Limitations of Fungal Biomarkers Detection
      • References
  • Index


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About the Editor

Kateryna Kon

Dr. Kateryna Kon, MD, PhD, currently works at the Department of Microbiology, Virology and Immunology at Kharkiv National Medical University, Kharkiv, Ukraine as an Associate Professor. Dr. Kon received the Best Young Scientist of Kharkiv Award in 2007. She has ten years of teaching and fifteen years of research experience. She is an editorial board member of six international peer-reviewed journals.

Dr. Kon's scientific contributions include more than 100 publications, 6 books and 18 scientific articles. The main focus of Dr. Kon’s research is antibiotic resistance in bacteria, coping with microbial resistance by plant essential oils and nanoparticles, microbiology of surgical and gynaecological infections, application of different statistical methods to analysis of biomedical data.

Affiliations and Expertise

Associate Professor, Department of Microbiology, Virology and Immunology, Kharkiv National Medical University, Kharkiv, Ukraine

Mahendra Rai

Dr Mahendra Rai: Professor and Head of the Department of Biotechnology at Amravati University in Maharashtra, India. He has published 210 research papers, more than 100 popular articles in Indian and foreign journals and 30 books from reputed publishers like Elsevier, Springer, CRC, Taylor and Francis and Scientific Publisher. He is a member of several scientific societies and has been a national Scholar for five years. He has received several prestigious awards, including the father T.A. Mathias award (1989) from the All India Association for Christian Higher Education, and the Medini award (1999) from the Department of Environment and Forest, Government of India. He also received SERC visiting fellowship by Department of Science and Technology (1996), INSA visiting fellowship by Indian National Science Academy (1998) and TWAS-UNESCO Associateship (2002), Italy. Dr. Rai serves as a referee for 20 international journals and is a member of editorial board of ten national and international journals. He has approximately three decades of teaching and research experience. The main focus of his research is plant and nanobased bioactives against human pathogenic microbes.

Affiliations and Expertise

Professor and Head, Department of Biotechnology, Amravati University, Maharashtra, India


"Those involved in practice, research, or education concerned with prevention or management of surgical infections would benefit from reading this book...Rating: 5 Stars"--Doody's.com,September 5 2014