Microarrays is an invaluable laboratory manual for anyone conducting experiments in the field of molecular biology or medical biochemistry who needs to understand and use microarray technologies. These technologies are especially appropriate in genome analysis, diagnostics, and studies involving differential gene expression.
Providing straightforward explanations, the authors demonstrate proven methods for biochip application and an overview of presently available instruments, biochips, and software. Chapters cover the different requirements for DNA and protein chips, as well as spotters and scanners. The book also covers high throughput screening, patent research, and the minimum requirements for setting up or expanding a microarray laboratory.
· Covers microarray applications, technology, and execution
· Written in an approachable yet informative tone
· Includes more than 100 detailed figures and graphs
· Examines the history of microarrays and their future potential
· Defines key terms from related disciplines
· Contains a full chapter on the importance of database research and patents
· Describes how to develop or improve one's own microarray laboratory
Laboratory practitioners such as students, instructors, and professionals who have knowledge in the fields of protein chemistry or molecular biology, but need a better understanding of microarray applications, instrumentation, and software.
Table of Contents
5. Instrumentation and Software
6. Execution of the Microarray Experiment
7. High Throughput Screening
8. Prospects for the Future
"This book presents an overview of microarrays and can function as a text for a short course in this area...recommended for any investigator/student wishing to better understand this key technique. I would encourage students to read this book if for no other reason than to become acquainted with both the utility and limitations of this approach."
- Eugene A Davidson, PhD, Georgetown University School of Medicine for DOODY'S