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Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms is the first book providing a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. The biophysical studies range from cell mechanics to neural science of worms and Drosophila. This book helps readers to understand the fundamentals in the development of these tools and learn the most recent advances in cellular and organismal biophysics enabled by these technologies.
- Comprehensive coverage of micro and nano-system technology and application to biophysical studies of cells and small organisms
- Highlights the most recent advances in cellular and organismal biophysics enabled by micro and nano systems
- Insightful outlook on future directions and trends in each chapter covering a sub-area of the book topic
Researchers and graduate students in disciplines of biomedical engineering, mechanical engineering, electrical engineering, biological, physics and biology, who are interested in learning the state-of-the-art technologies on micro and nano systems for studying biophysics of biological cells and small organisms. University instructors of graduate level courses in disciplines of biological and biomedical engineering, mechanical engineering, electrical engineering, and physics. Industrial practitioners (job role: R&D scientist, engineer, and manager) in sectors such as microelectromechanical systems (MEMS), nanotechnology, biotechnology, and medical devices
1. Microsystems for probing cellular forces and cellular mechanical properties
2. Force-sensing micropillar arrays for cell mechanics studies
3. Nanopillars/nanoneedles for probing live cells
4. Probing tissue mechanics at the cellular length-scale in cancer microenvironments
5. Microfluidic devices/systems for high-throughput cell manipulation and electroporation
6. High throughput 3D cellular platforms for screening biophysical microenvironmental signals
7. Acoustofluidic devices for cell biophysics
8. Microfluidic devices for neutrophil mitigation studies
9. Microrobots for cell biophysics
10. Robotic optical tweezers for cell biophysics
11. Robotic and microfluidic systems for single-cell microinjection
12. Biophysical phenotyping of C. elegans in a microfluidic chip for high-throughput drug screening
13. Microfluidic devices for immobilization, imaging, and high-throughput sorting of C. elegans
14. Microsystems for the study of thermotactic behavior of C. elegans
15. Microfluidics devices to study the effect of electric field on C. elegans and Danio rerio
16. Robotic micromanipulation systems for mechanical stimulation of Drosophila larvae
- No. of pages:
- © Academic Press 2022
- 1st September 2021
- Academic Press
- Paperback ISBN:
Xinyu Liu is an Associate Professor and the Percy Edward Hart Professor of Mechanical and Industrial Engineering at the University of Toronto. Prior to that, he was an Associate Professor and the Canada Research Chair in Microfluidics and BioMEMS in the Department of Mechanical Engineering at McGill University. At the University of Toronto, his research focuses on microfluidics, bioMEMS, and soft and micro robotics, with applications primarily in medicine and biology. He received the Canadian Rising Star in Global Health Award, the Douglas R. Colton Metal for Research Excellence, the McGill Christophe Pierre Award for Research Excellence, the MINE Outstanding Young Researcher Award, and seven best paper awards at major engineering and biomedical conferences. He is a fellow of the American Society of Mechanical Engineers.
Associate Professor and Percy Edward Hart Professor of Mechanical and Industrial Engineering, University of Toronto, Toronto, Canada
Yu Sun is a member of two national academies of Canada (Canadian Academy of Engineering; Academy of Science of the Royal Society of Canada). He is a Tier I Canada Research Chair and the Director of the University of Toronto’s Robotics Institute. His Advanced Micro and Nanosystems Laboratory specializes in developing innovative technologies and instruments for manipulating and characterizing cells, molecules, and nanomaterials. He was elected a fellow of the American Society of Mechanical Engineers, the Institute of Electrical and Electronics Engineers, the American Association for the Advancement of Science, the US National Academy of Inventors, and the American Institute of Medicine and Biomedical Engineering for his work on micro-nano devices and robotic systems. Among the awards he has received were an NSERC E.W.R. Steacie Memorial Fellowship, an NSERC Synergy Award for Innovation, the McLean Award, and the IEEE C.C. Gotlieb Computer Award.
Tier I Canada Research Chair and Director of the University of Toronto’s Robotics Institute, Toronto, Canada
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