Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms

Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies.

• Provides comprehensive coverage of micro and nano-system technologies and their applications in biophysical studies of cells and small organisms
• Highlights the most recent advances in cellular and organismal biophysics enabled by micro and nano systems
• Presents an insightful outlook on future directions and trends in each chaptera

Researchers and graduate students in disciplines of biomedical engineering, mechanical engineering, electrical engineering, biological, physics and biology, who are interested in learning the state-of-the-art technologies on micro and nano systems for studying biophysics of biological cells and small organisms. University instructors of graduate level courses in disciplines of biological and biomedical engineering, mechanical engineering, electrical engineering, and physics. Industrial practitioners (job role: R&D scientist, engineer, and manager) in sectors such as microelectromechanical systems (MEMS), nanotechnology, biotechnology, and medical devices

1. Microsystems for probing cellular forces and cellular mechanical properties
2. Force-sensing micropillar arrays for cell mechanics and mechanobiology
3. Vertical nanostructures for probing live cells
4. Probing tissue mechanics at the cellular length-scale in cancer microenvironments
5. Advanced microfluidic devices for cell electroporation and manipulation
6. High throughput 3D cellular platforms for screening biophysical microenvironmental signals
7. Acoustofluidic technology for cell biophysics
8. Microfluidic devices for neutrophil mitigation studies
9. Field controlled micro-nano manipulations and micro-nano robots
10. Robotic optical tweezers for cell biophysics
11. Robotic and microfluidic systems for single cell microinjection
12. Biophysical phenotyping of C. elegans in a microfluidic chip for high-throughput drug screening
13. Microfluidic devices for imaging and manipulation of C. elegans
14. Microsystems for the study of thermotactic behavior of C. elegans
15. Microfluidics devices to study the effect of electric field on C. elegans and Danio rerio
16. Force-controlled robotic systems for mechanical stimulation of drosophila larvae