Methods in Extracellular Matrix Biology

Methods in Extracellular Matrix Biology

1st Edition - January 5, 2018
  • Editor: Robert Mecham
  • Hardcover ISBN: 9780128122976
  • eBook ISBN: 9780128122983

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Description

Methods in Extra Cellular Matrix, Volume 142, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections devoted to Elastin, Quantification of collagen and elastin, Fibrillins, Lysyl oxidase, Fibulins, Matrilins, Hyaluronic Acid, Small leucine-rich proteoglycans, Syndecans, Fibronectin, SPARC, Thrombospondins, Tenascins, Collagen IV, Multi-photon analysis of ECM, Cell-derived extracellular matrices, Laminins, Fibrillar Collagens, Imaging ECM in developing embryos, Analysis of Matrix Degradation, Ultrastructural analysis of ECM, Versican and Large proteoglycans, and an ECM crosslink analysis. This series covers a wide array of topics about the extracellular matrix, including an understanding of crucial proteins and glycoproteins components of ECM.

Key Features

  • Contains contributions from experts in the field from across the world
  • Covers a wide array of topics on the extracellular matrix, including an understanding crucial proteins and the glycoproteins components of ECM
  • Includes analysis based topics, such as quantification of collagen and elastin, mulit-photon analysis of ECM and ECM crosslink analysis

Readership

Researchers and students in cell, molecular and developmental biology

Table of Contents

  • 1. Elastin
    2. Quantification of collagen and elastin
    3. Fibrillins
    4. Lysyl oxidase
    5. Fibulins
    6. Matrilins
    7. Hyaluronic Acid
    8. Small leucine-rich proteoglycans
    9. Syndecans
    10. Fibronectin
    11. SPARC
    12. Thrombospondins
    13. Tenascins
    14. Collagen IV
    15. Multi-photon analysis of ECM
    16. Cell-derived extracellular matrices
    17. Laminins
    18. Fibrillar Collagens
    19. Imaging ECM in developing embryos
    20. Analysis of Matrix Degradation
    21. Ultrastructural analysis of ECM
    22. Versican and Large proteoglycans
    23. ECM crosslink analysis

Product details

  • No. of pages: 468
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: January 5, 2018
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128122976
  • eBook ISBN: 9780128122983

About the Serial Editor

Robert Mecham

Dr. Robert Mecham is the Alumni Endowed Professor of Cell Biology and Physiology at Washington University School of Medicine. He holds joint appointments at the professorial level in Medicine, Pediatrics, and Bioengineering. He received his Bachelor of Science degree in Biology at the University of Utah in 1973 where he developed an interest in the extracellular matrix proteins that contribute to vascular function. He continued these studies during his graduate work at Boston University School of Medicine where he earned a Ph.D. in Biochemistry in 1977. Dr. Mecham was recruited to Washington University in 1977 in the Pulmonary Division, Department of Medicine, where his research focused on the underlying causes of emphysema and pulmonary hypertension. After a sabbatical at the National Institutes of Health as a Visiting Scientist, Dr. Mecham moved to the Department of Cell Biology and Physiology at Washington University where his laboratory continues to study extracellular matrix structure and assembly. Dr. Mecham has authored over 250 scientific papers and has edited 13 books. He was the first president of the American Society for Matrix Biology and has two honorary degrees from universities in Europe. He is a fellow of the American Association for the Advancement of Science and has served on editorial boards of major scientific journals. He has held numerous national and international scientific leadership positions and has served on important review and policy committees at all levels. At Washington University, Dr. Mecham twice served as interim chair of his Department. He has extensive involvement in medical and graduate school education and has received the university’s Distinguished Teacher Award three times and the Outstanding Faculty Mentor Award. Over 40 students and fellows have trained in his laboratory and have gone on to research and teaching positions in universities throughout the world. In recognition of his outstanding research and contributions to Washington University, Dr. Mecham was recently awarded the Carl and Gerty Cori Faculty Achievement Award.

Affiliations and Expertise

Alumni Endowed Professor of Cell Biology and Physiology, Washington University School of Medicine