Perspectives, Methods, and Applications

2nd Edition - December 1, 2022

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  • Editor: Muniyandi Nagarajan
  • Paperback ISBN: 9780323916318

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Metagenomics: Perspectives, Methods, and Applications, Second Edition provides thorough coverage of the growing field of metagenomics. Chapters from international experts examine methods for metagenomic analysis of microbiota, metagenomic computational tools, and recent metagenomic studies in various environments and clinical settings. This emphasis on applications makes the text particularly useful for applied researchers, practitioners, clinicians and students seeking to employ metagenomic approaches to advance knowledge in the biomedical and life sciences. Case-study based application chapters include topics ranging from viral metagenome profiling, metagenomics in oral disease and health, metagenomic insights into the human gut microbiome and metabolic syndromes, and more. This new edition has been fully updated to address the rapid growth and development of metagenomics applications that are discussed by experts who detail recent developments and fresh case studies. Newly added chapters instruct in methods and implications of metagenomics in areas of growing focus, such as microbiome research, clinical diagnosis, metagenomic epidemiology, wildlife conservation, zoonotic diseases and plant microbe interaction.

Key Features

  • Features a diverse range of chapters from international experts
  • Highlights the current state-of-the-art and recent advances in the field, along with current perspectives and case studies
  • Includes methods, techniques and various computational software tools and pipelines currently used in metagenomic studies
  • Provokes new thought and motivations for continued study, with next steps in research discussed at the end of each chapter


Human geneticists, biomedical researchers, molecular biologists, infectious disease experts, public health scientists, oral disease specialists, gastroenterologists, as well as students in these areas

Table of Contents

  • 1. Metagenomics: A Paradigm Shift in Microbiology
    2. Strategies for Taxonomic and Functional Annotation of Metagenomes
    3. Computational and Statistical Considerations in the Analysis of Metagenomic Data
    4. 16S rRNA-Based Taxonomy Profiling in the Metagenomics Era
    5. Measuring Microbiome Diversity with the Hill Numbers
    6. Analyzing High-throughput Microbial Amplicon Sequence Data Using Multiple Markers
    7. The Agave and Cacti microbiome: models for a planet under global warming
    8. Marine Invertebrate - Microbe Interactions: An insight in to Immunogenomics through Metagenomic Approach
    9. Novel Biological Resources Screened From Uncultured Bacteria by a Metagenomic Method
    10. Advances of Functional Metagenomics in Harnessing Thermozymes
    11. Comprehensive Exploration of the Rumen Microbial Ecosystem with Advancements in Metagenomics
    12. The animal metagenome and its application in the animal conservation
    13. Impending mental health issues during Covid-19 – Time for personalized nutrition based on the gut microbiota to tide over the crisis?
    14. SARS-CoV-2 and Genetic Variants: Alternative Therapies to Avert COVID-19 Pandemic
    15. Plant health in the era of metagenomics: Current state and future prospects

Product details

  • Language: English
  • Copyright: © Academic Press 2022
  • Published: December 1, 2022
  • Imprint: Academic Press
  • Paperback ISBN: 9780323916318

About the Editor

Muniyandi Nagarajan

Dr. M. Nagarajan received his M.Sc and PhD in Environmental Biotechnology from Manonmaniam Sundaranar University, Tirunelveli, Tamil Nadu, India. After his Ph.D program, he carried out his postdoctoral research at Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India and then at Laboratoire de Biologie Moléculaire de la Cellule, Ecole Normale Supérieure de Lyon, France. He was an Assistant Professor at Sri Paramakalyani Centre for Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tamil Nadu before joining Central University of Kerala in 2012. He is an editorial board member of Webmed Central Plus Genetics and reviewer of many peer-reviewed journals in the field of Genetics and Genomics including Gene and Biochemical Genetics. He has 18 publications in leading international journals including PLoS Genetics and Molecular Ecology. He has been awarded the Fast Track Young Scientists award by DST, Govt. of India. Presently, he is operating two major research projects funded by UGC and DST.

Affiliations and Expertise

Assistant Professor, Department of Genomic Science, School of Biological Science, Central University of Kerala, Kerala, India

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