Metabolic Pathways

Metabolic Pathways

Energetics, Tricarboxylic Acid Cycle, and Carbohydrates

3rd Edition - January 1, 1967

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  • Editor: David M. Greenberg
  • eBook ISBN: 9781483273532

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Metabolic Pathways, Third Edition, Volume I: Energetics, Tricarboxyl Acid Cycle, and Carbohydrates provides information pertinent to the determination of the sequential steps of the different metabolic pathways and the isolation and characterization of the enzymes catalyzing the several steps. This book discusses the chemical steps in the metabolism of the constituents of major significance in living organisms. Organized into seven chapters, this edition begins with an overview of the concept of free energy and the various methods of obtaining free energy data. This text then examines the relations between free energy and other quantities of direct interest, such as equilibrium constants, electromotive forces, and heats of reactions. Other chapters consider the transformation of energy from one form to another that is accomplished in living systems by specialized structures. The final chapter deals with the importance of L-ascorbic acid in the prevention of scurvy and its mode of action at the molecular level. This book is a valuable resource for biochemists.

Table of Contents

  • List of Contributors


    Contents of Other Volumes

    Chapter I Free Energy and Entropy in Metabolism

    I. Introduction

    II. Free Energy and Its Determination

    III. Heat of Reaction

    IV. Entropy

    V. Sources of Energy

    VI. Release of Energy


    Chapter 2 The Mitochondrial System of Enzymes

    I. Biochemical Machines

    II. Structure and Ultrastructure of the Mitochondrion

    III. The Integrated Reactions of Mitochondria

    IV. The Citric Acid Cycle

    V. The Electron Transfer System

    VI. Oxidative Phosphorylation and the Generation of the Energized State


    Chapter 3 Glycolysis

    I. Introduction

    II. Enzymes of the Glycolytic Cycle

    III. Regulation of Glycolysis


    Chapter 4 The Tricarboxylic Acid Cycle

    I. Introduction

    II. The Cycle in Animal Tissues

    III. Reactions of the Cycle

    IV. The Cycle in Microorganisms

    V. The Cycle in Plants

    VI. Modified Tricarboxylic Acid Cycles

    VII. Role of the Tricarboxylic Acid Cycle in the Synthesis of Cell Constituents

    VIII. Reactions Leading from Foodstuffs to the Tricarboxylic Acid Cycle

    IX. Other Reactions Leading to and from the Cycle

    X. Metabolic Control and the Cycle

    XI. The Cycle under Anaerobic Conditions

    XII. Envoy


    Chapter 5 Other Pathways of Carbohydrate Metabolism

    I. Introduction

    II. The Pent ose Phosphate Pathway

    III. Oxidative Metabolism of Nonphosphorylated Hexose

    IV. Phosphorylation of Hexoses Not Requiring Nucleoside Triphosphates

    V. Pentose Metabolism in Bacteria

    VI. Pentose Metabolism in Plants

    VII. Galactose Metabolism

    VIII. Inositol Metabolism

    IX. Metabolism of Nonphosphorylated Uronic Acids

    X. Deoxyribose Metabolism


    Chapter 6 Biosynthesis of Complex Saccharides

    I. Photosynthetic Intermediates Leading to the Formation of Monosaccharides

    II. Processes Involved in Complex Saccharide Formation

    III. Synthesis of α-1, 4-D-Glucose Chains of Glycogen and Starch by the Action of Phosphorylase

    IV. Structure of Glycogen and Amylopectin

    V. Synthesis of Branched Polysaccharides

    VI. Synthesis of Starch-Glycogen Type of Polysaccharides by Transglycosylases

    VII. Synthesis of Polysaccharides by Transglycosylation

    VIII. Synthesis of Nucleoside Diphosphate Sugars and Their Interconversions

    IX. Synthesis of Oligosaccharides from Nucleoside Diphosphate Sugars by Transglycosylation

    X. Synthesis of Glycosides from Nucleoside Diphosphate Sugars by Transglycosylation

    XI. Synthesis of Polysaccharides from Sugar Diphosphate Nucleosides by Transglycosylation

    XII. Capsular Pneumococcus Polysaccharides

    XIII. Synthesis of Bacterial Cell-Wall Lipopolysaccharides

    XIV. Synthesis of Teichoic Acids

    XV. Synthesis of Glycoproteins and Mucopolysaccharides

    XVI. Mechanism of Transglycosylation

    XVII. Addendum


    Chapter 7 Ascorbic Acid

    I. Introduction

    II. Biosynthesis of L-Ascorbic Acid in Animals

    III. Inability of Primates and Guinea Pigs to Synthesize L-Ascorbic Acid

    IV. Biosynthesis of L-Ascorbic Acid in Plants

    V. Catabolism of L-Ascorbic Acid in Animals

    VI. L-Ascorbic Acid, an Intermediate in Carbohydrate Metabolism

    VII. Glucuronic Acid Pathway of Glucose Metabolism

    VIII. Metabolism of D-Ascorbic Acid


    Author Index

    Subject Index

Product details

  • No. of pages: 476
  • Language: English
  • Copyright: © Academic Press 1967
  • Published: January 1, 1967
  • Imprint: Academic Press
  • eBook ISBN: 9781483273532

About the Editor

David M. Greenberg

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