Metabolic Conjugation and Metabolic Hydrolysis - 1st Edition - ISBN: 9780122576034, 9781483269467

Metabolic Conjugation and Metabolic Hydrolysis

1st Edition

Volume III

Editors: William H. Fishman
eBook ISBN: 9781483269467
Imprint: Academic Press
Published Date: 1st January 1973
Page Count: 488
Sales tax will be calculated at check-out Price includes VAT/GST
72.95
43.99
54.95
Unavailable
Price includes VAT/GST
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

Metabolic Conjugation and Metabolic Hydrolysis, Volume III is a comprehensive account of the status of metabolic conjugation and metabolic hydrolysis. Topics covered range from the metabolism of steroid hormone conjugates and the genetic control of acid hydrolases to acetylation of drugs. Biochemical mechanisms in methyl group transfer are also discussed, along with the bilirubin conjugates of the human bile.

Comprised of eight chapters, this volume first looks at the biosynthesis of animal glycoproteins before turning to an analysis of the metabolism of the conjugates of steroid hormones. The reader is then introduced to the genetic mechanisms that regulate acid hydrolases; control of metabolic hydrolysis in the lysosome-vacuolar apparatus; and the biochemical mechanisms underlying methyl group transfer. The final chapter is devoted to membrane phosphohydrolases, with emphasis on certain common features of membrane enzymes or of enzymes associated with membranes. Membrane transferases and hydrolases are also considered, including adenosine triphosphatase and adenyl cyclase.

This book will be a useful resource for biologists, biochemists, physiologists, and pharmacologists.

Table of Contents


List of Contributors


Preface


Contents of Other Volumes


The Biosynthesis of Animal Glycoproteins


I. Introduction


II. Chemical Structures of Glycoproteins


III. Biosynthesis of Nucleotide Sugars


IV. Biosynthesis of Asn-GlcNAc-Type Prosthetic Groups


V. Biosynthesis of Ser-GalNAc and Thr-GalNAc-Type Prosthetic Groups


VI. Biosynthesis of Hyl-Gal-Type Prosthetic Groups


VII. Biosynthesis of Prosthetic Groups with Unknown Linkage Regions


VIII. Summation and General Conclusions


References


On the Significance of the Metabolism of Steroid Hormone Conjugates


I. Introduction


II. 1930-1960: Steroid Conjugation as Detoxication Products of Hormone Metabolism


III. The 1960's: Steroid Conjugate Metabolism


IV. For the Future: Biological Activity?


V. Conclusions


References


The Genetic Control of Acid Hydrolases


I. Introduction


II. Subcellular Integration of Acid Hydrolases


III. Genetic Control of the Temporal Accumulation of Glucuronidase


IV. A Single-Gene Approach to the Low Glucuronidase Phenotype


References


Control of Metabolic Hydrolysis in the Lysosome-Vacuolar Apparatus


I. Introduction


II. Lysosome-Vacuolar Apparatus: A Definition and Model


III. Synthesis of Acid Hydrolases


IV. The Dynamic Process of Vesiculation


V. Vacuolar Apparatus: Interaction of Primary-Secondary Lysosome


VI. Acid Hydrolase Activity within the Vacuolar Apparatus


VII. Endocytosis-Exocytosis


VIII. Summary and Epilog


References


Acetylation of Drugs


I. Acetylation of Drugs and Foreign Compounds in Man and Animals


II. Inh

Details

No. of pages:
488
Language:
English
Copyright:
© Academic Press 1973
Published:
Imprint:
Academic Press
eBook ISBN:
9781483269467

About the Editor

William H. Fishman

Ratings and Reviews