Metabolic and Degenerative Diseases of the Central Nervous System - 1st Edition - ISBN: 9780121652500, 9780080536255

Metabolic and Degenerative Diseases of the Central Nervous System

1st Edition

Pathology, Biochemistry, and Genetics

Authors: Jorge Cervos-Navarro Henry Urich
eBook ISBN: 9780080536255
Imprint: Academic Press
Published Date: 28th September 1995
Page Count: 873


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Metabolic and Degenerative Diseases of the Central Nervous System is a comprehensive reference work that provides the neuroscience community with valuable, current, and scholarly summaries on every known degenerative disorder. Written by two world-renowned neuropathologists, the book provides an optimal basis for the understanding of metabolic and degenerative diseases of the central nervous system and presents a synthesis that serves the needs of today's investigators in neuropathology, neurology, neuroradiology, neurosurgery, neuropediatrics, general pathology, and geriatrics. This is the only comprehensive authoritative review of the neuropathology of metabolic and neurodegenerative diseases. In the future, genetic engineering is expected to provide effective molecular therapy for the countless diseases currently termed "metabolic" or "degenerative." Metabolic and Degenerative Diseases of the Central Nervous System is intended to provide a sound morphological platform for these forthcoming events.

Key Features

@introbul:Key Features @bul:* Neuropathology of every disease correlated with an overview of the medical and general pathological changes

  • Authored by neuropathologists with international reputations as educators and scientists
  • Highlighted with illustrations from the authors' own archives and contributions from colleagues throughout the world


Researchers and academic clinicians in neuroscience, neurology, pathology, as well as researchers in biochemistry and genetics will be interested.

Table of Contents

Metabolic Diseases of the Nervous System: Introduction. Disorders of Carbohydrate Metabolism. Disorders of Glycosaminoglycan Metabolism (Mucopolysaccharidoses). Mucolipidoses. Disorders of Amino Acid Metabolism. MetabolicDisorder of the Urea Cycle. Disorders of Protein Metabolism. Disorders of Lipid Metabolism. Disorders of Purine Metabolism. Disorders of Mineral Metabolism. Disorders of Pigment Metabolism.

Degenerative Diseases of the Central Nervous System: Introduction. Degenerative Diseases of the Cerebral Cortex and White Matter. Degenerative Diseases of the Thalamus, the Basal Ganglia, and the Midbrain. Degenerative Diseases of the Cerebellum, Brain Stem, and Spinal Cord (Spinocerebellar Degenerations). Predominantly Spinal Atrophies. Atrophies of the Motor Neurons. Peripheral and Autonomic Neuropathies with Involvement of the Central Nervous System. Miscellaneous Conditions. Congenital Cerebral Abnormalities with Skeletal Malformations. Epilepsy in Neurogenerative Disorders. References. Subject Index.


No. of pages:
© Academic Press 1995
Academic Press
eBook ISBN:

About the Author

Jorge Cervos-Navarro

Affiliations and Expertise

Freie Universitat Berlin, Germany

Henry Urich

Affiliations and Expertise

University of London, U.K.


@qu:"...if you are looking for concise information or even the remotest metabolic or degenerative disease, you will find the basic information easily at hand...the authors are to be congratulated on mastering a task which most of us would not even have had the courage to begin." @source:--Paul Kleihues, International Agency for Research Cancer (IARC), in BRAIN PATHOLOGY @qu:"Drs. Cerves-Navarro and Urich... have come to our aid. The authors have collected, digested, and summarized over 3,000 published reports and studies, and have presented this information in a consistent, clear format that makes this book a wonderful reference... All of the sections are thoroughly referenced... A job well done." @source:--Robert E Mrak, University of Arkansas for Medical Sciences, in HUMAN PATHOLOGY @qu:"The book represents a tour de force for the two authors, who are renaissance neuropathologists, an increasingly uncommon breed of neuropathologists these days... a valuable resource for the neuropathologists for whom it will provide sufficient information for most practical purposes and a starting point for more detailed investigation, especially for rare conditions." @source:--Dennis W. Dickson, Albert Einstein College of Medicine, in CELL