Membrane Research: Classic Origins and Current Concepts - 1st Edition - ISBN: 9780123643735, 9781483271996

Membrane Research: Classic Origins and Current Concepts

1st Edition

Editors: A. L. Muggleton-Harris
eBook ISBN: 9781483271996
Imprint: Academic Press
Published Date: 28th May 1981
Page Count: 454
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Membrane Research: Classic Origins and Current Concepts is a special volume of the International Review of Cytology dedicated to Dr. Danielli on the occasion of his retirement from official duties. The central theme of the volume is membranes. The diversity of topics ranges from the biogenesis of membranes and their components, to the use of optical and lectin probes as a means to study the structure, physiology, and interactions of cell components and organelles in plant and animal systems. The book begins with a study on the cell surface of the mammalian embryo and the events associated with the formation of the differentiated blastocyst. This is followed by separate chapters on the structural associations between the inner and outer bacterial membrane; the interactions of cell wall and membrane in plant cells; the morphological and functional aspects of membranes; and methods for studying the physiology of cell and organelles at the membrane level. Subsequent chapters deal with the synthesis of cellular proteins and glycoproteins; techniques for fixing and preserving the ultrastructure of the membrane; the synthesis of artificial organelles; and the effects of drugs and chemicals on membrane transport utilizing kidney tissue and vesicles. This book provides an outstanding reference source for all scientific researchers and teachers.

Table of Contents

List of Contributors

Supplements in Series




Membrane Events Associated with the Generation of a Blastocyst

I. Cell Position, Cell Fate, and Selective Gene Expression

II. The Generation of Inside: Outside Differences in the Mouse Morula

III. The Maintenance of Two Cell Lineages in the Mouse Morula

IV. The Role of Cell Membranes and Interactions in the Cytodifferentiation of a Blastocyst

V. The Role of the Membrane in Morphogenesis

VI. Conclusions


Structural and Functional Evidence of Cooperativity between Membranes and Cell Wall in Bacteria

I. Introduction

II. Ultrastructure of the Cell Envelope: the Outer Membrane

III. Intramembranous Particles

IV. Periplasmic Space

V. Inner (Protoplasmic) Membrane

VI. Evidence for Structural Associations between the Inner and Outer Membrane

VII. The Functional Cooperativity between the Membranes of the Cell Envelope

VIII. Responses of the Cell: Cell Surface Growth and Functional Mosaicism


Plant Cell Surface Structure and Recognition Phenomena with Reference to Symbioses

I. Introduction

II. Plant Lectins

III. The Plant Cell Wall and Recognition Phenomena

IV. Plant-Microbe Symbioses

V. Recent Attempts to Synthesize Plant-Microbe Symbioses

VI. The Use of Lectins to Probe Symbioses

VII. Concluding Remarks


Membranes and Cell Movement: Interactions of Membranes with the Proteins of the Cytoskeleton

I. Introduction

II. Components of the Cytoskeleton

III. Interactions of Cytoskeletal Elements with the Plasma Membrane in Selected Systems

IV. Afterword


Electrophysiology of Cells and Organelles: Studies with Optical Potentiometric Indicators

I. Introduction

II. Nonexcitable Cells

III. Organelles


Synthesis and Assembly of Membrane and Organelle Proteins

I. Introduction

II. Structure of Integral Membrane Proteins and of Organelles

III. Biosynthesis of the Envelope Glycoproteins of Vesicular Stomatitis Virus, and Sindbis Virus, and of Similar Glycoproteins

IV. Biosynthesis of Other Transmembrane Proteins—Rhodopsin and the Anion Transport Protein

V. Biogenesis of Integral, but Not Transmembrane, Proteins

VI. Biosynthesis of Mitochondrial and Chloroplast Proteins

VII. Biogenesis of Lysosomes

VIII. Biogenesis of Peroxisomes

IX. Biosynthesis of Extrinsic Membrane Proteins

X. Conclusions and Prospects


The Importance of Adequate Fixation in Preservation of Membrane Ultrastructure

I. The Unit Membrane Model versus the Unit Membrane Image

II. Preservation of Membrane Ultrastructure

III. New Approaches to the Localization of Proteins within Membranes

IV. Coda


Liposomes—As Artificial Organelles, Topochemical Matrices, and Therapeutic Carrier Systems

I. Introduction

II. Reconstitution of Organellar Function

III. The Topochemical Matrix

IV. The Liposome as Therapeutic Carrier

V. Conclusions


Drug and Chemical Effects on Membrane Transport

I. Introduction

II. Techniques

III. Renal Organic Anion and Cation Transport

IV. Drug and Chemical Effects on Transport

V. Summary



Curriculum Vitae: James F. Danielli

Publications: James F. Danielli


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© Academic Press 1981
Academic Press
eBook ISBN:

About the Editor

A. L. Muggleton-Harris

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