Membrane Research: Classic Origins and Current Concepts

List of Contributors

Supplements in Series

Foreword

Preface

Reminiscence

Membrane Events Associated with the Generation of a Blastocyst

I. Cell Position, Cell Fate, and Selective Gene Expression

II. The Generation of Inside: Outside Differences in the Mouse Morula

III. The Maintenance of Two Cell Lineages in the Mouse Morula

IV. The Role of Cell Membranes and Interactions in the Cytodifferentiation of a Blastocyst

V. The Role of the Membrane in Morphogenesis

VI. Conclusions

References

Structural and Functional Evidence of Cooperativity between Membranes and Cell Wall in Bacteria

I. Introduction

II. Ultrastructure of the Cell Envelope: the Outer Membrane

III. Intramembranous Particles

IV. Periplasmic Space

V. Inner (Protoplasmic) Membrane

VI. Evidence for Structural Associations between the Inner and Outer Membrane

VII. The Functional Cooperativity between the Membranes of the Cell Envelope

VIII. Responses of the Cell: Cell Surface Growth and Functional Mosaicism

References

Plant Cell Surface Structure and Recognition Phenomena with Reference to Symbioses

I. Introduction

II. Plant Lectins

III. The Plant Cell Wall and Recognition Phenomena

IV. Plant-Microbe Symbioses

V. Recent Attempts to Synthesize Plant-Microbe Symbioses

VI. The Use of Lectins to Probe Symbioses

VII. Concluding Remarks

References

Membranes and Cell Movement: Interactions of Membranes with the Proteins of the Cytoskeleton

I. Introduction

II. Components of the Cytoskeleton

III. Interactions of Cytoskeletal Elements with the Plasma Membrane in Selected Systems

IV. Afterword

References

Electrophysiology of Cells and Organelles: Studies with Optical Potentiometric Indicators

I. Introduction

II. Nonexcitable Cells

III. Organelles

References

Synthesis and Assembly of Membrane and Organelle Proteins

I. Introduction

II. Structure of Integral Membrane Proteins and of Organelles

III. Biosynthesis of the Envelope Glycoproteins of Vesicular Stomatitis Virus, and Sindbis Virus, and of Similar Glycoproteins

IV. Biosynthesis of Other Transmembrane Proteins—Rhodopsin and the Anion Transport Protein

V. Biogenesis of Integral, but Not Transmembrane, Proteins

VI. Biosynthesis of Mitochondrial and Chloroplast Proteins

VII. Biogenesis of Lysosomes

VIII. Biogenesis of Peroxisomes

IX. Biosynthesis of Extrinsic Membrane Proteins

X. Conclusions and Prospects

References

The Importance of Adequate Fixation in Preservation of Membrane Ultrastructure

I. The Unit Membrane Model versus the Unit Membrane Image

II. Preservation of Membrane Ultrastructure

III. New Approaches to the Localization of Proteins within Membranes

IV. Coda

References

Liposomes—As Artificial Organelles, Topochemical Matrices, and Therapeutic Carrier Systems

I. Introduction

II. Reconstitution of Organellar Function

III. The Topochemical Matrix

IV. The Liposome as Therapeutic Carrier

V. Conclusions

References

Drug and Chemical Effects on Membrane Transport

I. Introduction

II. Techniques

III. Renal Organic Anion and Cation Transport

IV. Drug and Chemical Effects on Transport

V. Summary

References

Index

Curriculum Vitae: James F. Danielli

Publications: James F. Danielli