Description

Membrane proteins continue to be prime drug targets because they perform essential processes in the cell including controlling the flow of information and materials between cells and mediating activities like hormone action and nerve impulses. The study of membrane proteins could lead to new and improved pharmaceutical treatments for a wide range of illnesses such as heart disease, cystic fibrosis and depression.

This volume reviews the latest developments in the field.

Key Features

* Discusses new discoveries, approaches, and ideas in the field of membrane proteins and reviews how they are being used to develop new drugs
* Contributions from leading scholars and industry experts
* Reference guide for researchers involved in molecular biology and related fields

Readership

Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.

Table of Contents

  1. Inverse Agonism at Serotonin and Cannabinoid Receptors

         Vincent J. Aloyo, Kelly A. Berg, William P. Clarke, Umberto Spampinato, and John A. Harvey

2.    G protein-coupled receptor heteromers as new targets for drug development

    Sergi Ferré, Gemma Navarro, Vicent Casadó, Antoni Cortés, Josefa Mallol, Enric I. Canela, Carme Lluís and Rafael Franco

3.    Receptor activity modifying proteins and their potential as drug targets

    Denise L. Wootten, John Simms, Debbie L. Hay, Arthur Christopoulos and Patrick M. Sexto

    4.  Regulators of G Protein Signaling Proteins As Targets For Drug Discovery

    Benita Sjögren, Levi L. Blazer and Richard R. Neubig

5.    Escorts Take the Lead: Molecular Chaperones as Therapeutic Targets

    Dumaine Williams and Lakshmi A. Dev

    6.    The T1r2/T1r3 Sweet Receptor and Trpm5 Ion Channel: Taste Targets With Therapeutic Potential

    Dennis Sprous and R. Kyle Palmer

    7.     Membrane-associated enzymatic synthesis

Edward A. Esposito and Robert Weis

Details

No. of pages:
270
Language:
English
Copyright:
© 2010
Published:
Imprint:
Academic Press
eBook ISBN:
9780123812896
Print ISBN:
9780123812889

About the serial-volume-editor

Charles.A Lunn

Affiliations and Expertise

Schering-Plough Research Institute, New Jersey, USA

Reviews

PRAISE FOR THE SERIES:
"Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal