Membrane Proteins as Drug Targets

Membrane Proteins as Drug Targets

1st Edition - August 24, 2010

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  • Editor: Charles.A Lunn
  • eBook ISBN: 9780123812896

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Membrane proteins continue to be prime drug targets because they perform essential processes in the cell including controlling the flow of information and materials between cells and mediating activities like hormone action and nerve impulses. The study of membrane proteins could lead to new and improved pharmaceutical treatments for a wide range of illnesses such as heart disease, cystic fibrosis and depression. Membrane Proteins as Drug Targets reviews the latest developments in the field.

Key Features

  • Discusses new discoveries, approaches, and ideas in the field of membrane proteins and reviews how they are being used to develop new drugs
  • Contributions from leading scholars and industry experts
  • Reference guide for researchers involved in molecular biology and related fields


Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.

Table of Contents

    1. Inverse Agonism at Serotonin and Cannabinoid Receptors

             Vincent J. Aloyo, Kelly A. Berg, William P. Clarke, Umberto Spampinato, and John A. Harvey

    2.    G protein-coupled receptor heteromers as new targets for drug development

      Sergi Ferré, Gemma Navarro, Vicent Casadó, Antoni Cortés, Josefa Mallol, Enric I. Canela, Carme Lluís and Rafael Franco

    3.    Receptor activity modifying proteins and their potential as drug targets

      Denise L. Wootten, John Simms, Debbie L. Hay, Arthur Christopoulos and Patrick M. Sexto

      4.  Regulators of G Protein Signaling Proteins As Targets For Drug Discovery

      Benita Sjögren, Levi L. Blazer and Richard R. Neubig

    5.    Escorts Take the Lead: Molecular Chaperones as Therapeutic Targets

      Dumaine Williams and Lakshmi A. Dev

      6.    The T1r2/T1r3 Sweet Receptor and Trpm5 Ion Channel: Taste Targets With Therapeutic Potential

      Dennis Sprous and R. Kyle Palmer

      7.     Membrane-associated enzymatic synthesis

    Edward A. Esposito and Robert Weis

Product details

  • No. of pages: 270
  • Language: English
  • Copyright: © Academic Press 2010
  • Published: August 24, 2010
  • Imprint: Academic Press
  • eBook ISBN: 9780123812896

About the Serial Volume Editor

Charles.A Lunn

Affiliations and Expertise

Schering-Plough Research Institute, New Jersey, USA

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