Membrane Fluidity in Biology

Contributors

Preface

Contents of Other Volumes


1. Membrane Lipids, Membrane Fluidity, and Enzyme Activity

I. Introduction

II. Models of Membrane Structure

III. Membrane Lipids, Membrane Fluidity, and Enzyme Activity

IV. Concluding Remarks and Future Directions

Addendum

References


2. Membrane Fluidity and the Function of the Ca2+-ATPase of Sarcoplasmic Reticulum

I. Structure and Function of Sarcoplasmic Reticulum: General Aspects

II. Role of Lipids in Sarcoplasmic Reticulum Function

III. Effect of Temperature on Ca2+ Transport and Ca2+-ATPase Activity

IV. Fluidity and Function: Spectroscopic Studies

V. Boundary Lipids

VI. Concluding Remarks

References


3. The Role of Cholesterol in Regulating Membrane Fluidity

I. Introduction

II. Sample Systems

III. Lipid Phase Transitions

IV. Effect of Cholesterol on the Phase Transition

V. Cholesterol's Effect on Lipid Chain Fluidity

VI. Phase Behavior of Cholesterol-Phospholipid Systems

VII. Anomalous Behavior of a Cholesterol Analog

VIII. Head Group Interactions

IX. The Phospholipid Pretransition

X. A New Look at Hydrogen Bonding

XI. Stoichiometry of Cholesterol-Rich Domains

XII. Structure of Cholesterol-Rich Domains

XIII. Role of Sterols in Natural Membranes

References


4. Membrane Lipid Fluidity, Phase State, and Membrane Function in Prokaryotic Microorganisms

I. Introduction

II. Definition and Measurement of Membrane Fluidity

III. Methods of Manipulating Membrane Lipid Fluidity

IV. Arrhenius Plots of Growth Rates and of Membrane Transport Systems and Enzymes

V. Membrane Lipid Fluidity and Phase State and Cell Growth

VI. Membrane Lipid Fluidity and Phase State and Membrane Transport

VII. Membrane-Bound Enzyme Activities

VIII. Conclusions

References


5 . The Modulation of Glycosyltransferase Activity in Golgi Membranes

I. Introduction

II. Structural Organization of the Golgi Complex

III. The Glycosylation Process in the Golgi Apparatus

IV. Role of Lipids in Golgi Function

V. Concluding Remarks

References


6. Regulation of Membrane Fluidity by Phospholipid Methylation

I. Introduction

II. Heterogeneity of Membrane Structure

III. Factors Involved in Membrane Fluidity

IV. Control of Membrane Fluidity by Phospholipid Methylation

V. Alterations in Physiological Functions and Membrane Fluidity by Phospholipid Methylation

VI. Conclusion

References


7. Role of Proteins in the Fusion of Biological Membranes

I. Introduction

II. Role of Viral Envelope Protein in Virus-Host Cell Fusion

III. Role of Protein in Myoblast Fusion

IV. Role of Proteins in Exocytosis

References

Index