Medicinal Plants as Anti-infectives

Medicinal Plants as Anti-infectives

Current Knowledge and New Perspectives

1st Edition - March 31, 2022

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  • Editor: Francois Chassagne
  • eBook ISBN: 9780323910002
  • Paperback ISBN: 9780323909990

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Description

Medicinal Plants as Anti-infectives: Current Knowledge and New Perspectives provides comprehensive and updated data on medicinal plants and plant-derived compounds used as antimicrobials in a range of locations (such as the Balkans, Colombia, India, Lebanon, Mali, Pakistan, Southeast Asia, South Africa, and West Africa). It also provides an overview on the most recent innovations and regulations in the field of drug discovery from ethnobotanical sources. This book will help readers to better appreciate the role of plants and phytomedicines as anti-infectives, to better assess the health benefits of plant-derived products, to help implement new methodologies for studying medicinal plants, and to guide future researchers in the field. Medicinal Plants as Anti-infectives: Current Knowledge and New Perspectives is a valuable resource for students, academic scientists, and researchers from the fields of ethnobotany, pharmacy, medicinal chemistry, and microbiology, as well as for professionals working in national or international health agencies, or in pharmaceutical industries.

Key Features

  • Provides an overview of new methods and tools developed in the field of drug discovery from ethnobotanical sources (e.g., DNA barcoding, metabolomics, quorum quenching)
  • Contains real-world insights from experts in the field
  • Presents specific research program results to inspire further research in additional regions

Readership

Scientists and students in the fields of phytomedicine, pharmacognosy, ethnobotany, ethnopharmacology, and phytochemistry. Pharmaceutical companies and national/international health agencies

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • List of contributors
  • Preface
  • Part I: Medicinal plants as anti-infectives: an appraisal of current knowledge worldwide
  • Chapter 1. A review of medicinal plants used as antimicrobials in Colombia
  • Abstract
  • Introduction
  • Materials and methods
  • Plants traditionally used in Colombia as antimicrobials
  • Biological evaluation as antimicrobials of plant extracts in Colombia
  • Antibacterial evaluation of 25 native plants of the Colombian Caribbean region against strains of Escherichia coli, Klebsiella pneumonia, and Pseudomonas aeruginosa resistant to carbapenems and Staphylococcus aureus resistant to methicillin (Colciencias, Project code: 110777757752)
  • Conclusions
  • References
  • Chapter 2. Plants used in Lebanon and the Middle East as Antimicrobials
  • Abstract
  • Introduction: overview on medicinal plants and their traditional uses as antimicrobials in Lebanon
  • Lebanese plants with antimicrobial activity
  • Conclusion
  • Acknowledgment
  • References
  • Chapter 3. Medicinal plants in the Balkans with antimicrobial properties
  • Abstract
  • Introduction
  • Medicinal plants with antimicrobial properties
  • Conclusions
  • References
  • Chapter 4. Medicinal plants used in South Africa as antibacterial agents for wound healing
  • Abstract
  • Introduction
  • Pathophysiology of wound healing
  • Wound infection
  • Currently available treatments and products
  • Bacteria associated with infections of dermal wounds
  • South African medicinal plant species with activity against wound-associated bacteria
  • Compounds present in plants traditionally used for wound healing in South Africa
  • Discussion
  • Conclusion
  • Index
  • Glossary
  • References
  • Chapter 5. The use of South African medicinal plants in the pursuit to treat gonorrhea and other sexually transmitted diseases
  • Abstract
  • Introduction
  • Background on gonorrhea
  • Status of available treatments for gonorrhea
  • Selected South African plants used in traditional medicine for the treatment of sexually transmitted diseases and their bioactivity
  • Conclusion
  • References
  • Chapter 6. Antibacterial activity of some selected medicinal plants of Pakistan
  • Abstract
  • Introduction
  • Antibacterial properties of different medicinal plants from Pakistan
  • Conclusion
  • References
  • Chapter 7. Medicinal plants used as antidiarrheal agents in the lower Mekong basin
  • Abstract
  • Introduction
  • Traditional medicine for diarrheal diseases in the Mekong Basin
  • Models assessing the effect of plants on the signs and symptoms of diarrhea
  • Models assessing the antimotility and antisecretory activities
  • Models assessing the antiinfective properties
  • Medicinal plants used for diarrhea in the lower Mekong basin
  • Discussion of some selected plant species
  • Conclusion
  • References
  • Chapter 8. Medicinal plants from West Africa used as antimalarial agents: an overview
  • Abstract
  • Introduction
  • Traditional use of medicinal plants in West Africa
  • Plant extracts and plant compounds validated by in vitro and/or in vivo approach
  • The case of Artemisia in West Africa
  • Conclusion
  • References
  • Part II: Medicinal plants as anti-infectives: recent innovations and regulations
  • Chapter 9. Mycobacterial quorum quenching and biofilm inhibition potential of medicinal plants
  • Abstract
  • Introduction
  • Significance of quorum quenching research
  • Current state of quorum quenching research
  • Quorum sensing versus quorum quenching
  • Biofilms
  • Biofilms and Mycobacterium tuberculosis
  • Virulence factors
  • Virulence factors and Mycobacterium tuberculosis
  • Medicinal plants as quorum quenching agents
  • Medicinal plants and mycobacterial quorum quenching
  • Phytochemicals used in bacterial quorum quenching
  • Conclusion
  • References
  • Chapter 10. Untargeted metabolomics for the study of antiinfective plants
  • Abstract
  • Introduction
  • Plants as sources of antiinfective agents
  • Bioassay-guided fractionation
  • Metabolomics
  • Methods of detection
  • Data analysis
  • Biochemometrics
  • Metabolomics-driven antiinfective discovery from plants
  • Challenges and future directions
  • Metabolome coverage
  • Annotation/identification
  • Synergy
  • Conclusions
  • References
  • Chapter 11. Value chains and DNA barcoding for the identification of antiinfective medicinal plants
  • Abstract
  • Introduction
  • Materials and methods
  • Results and discussion
  • Future perspectives
  • References
  • Chapter 12. Fungal endophytes: a source of antibacterial and antiparasitic compounds
  • Abstract
  • Introduction
  • Antimicrobial compounds from endophytic fungi
  • Discussion and conclusion
  • References
  • Chapter 13. Antiviral potential of medicinal plants: a case study with guava tree against dengue virus using a metabolomic approach
  • Abstract
  • Introduction
  • Case study: metabolomics reveal antidengue compounds isolated from Psidium guajava
  • Acknowledgments
  • References
  • Chapter 14. How history can help present research of new antimicrobial strategies: the case of cutaneous infections’ remedies containing metals from the Middle Age Arabic pharmacopeia
  • Abstract
  • Introduction
  • Brief history of Arabic medicine
  • Cutaneous infections and medications
  • Conclusion
  • References
  • Chapter 15. Improved traditional medicine for infectious disorders in Mali
  • Abstract
  • Introduction
  • General information on improved traditional medicines
  • Categories of improved traditional medicines
  • Marketing authorization files for ITMs in Mali
  • Historical development of ITMs in Mali
  • ITMs in the management of infectious diseases
  • Conclusion and perspectives
  • Index of ITMs
  • References
  • Chapter 16. Selecting the most promising local treatments: retrospective treatment-outcome surveys and reverse pharmacology
  • Abstract
  • Introduction
  • Clinical efficacy
  • Reverse pharmacology approach
  • New and promising approaches for the laboratory stage in a reverse pharmacology approach
  • Conclusion and perspectives
  • Acknowledgments
  • References
  • Chapter 17. Nagoya Protocol and access to genetic resources
  • Abstract
  • Introduction
  • History and evolution of concepts
  • Discussion
  • New trends and evolutions
  • Conclusion
  • Acknowledgments
  • References
  • Index

Product details

  • No. of pages: 586
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: March 31, 2022
  • Imprint: Academic Press
  • eBook ISBN: 9780323910002
  • Paperback ISBN: 9780323909990

About the Editor

Francois Chassagne

François Chassagne is a pharmacist and researcher at the IRD (French National Research Institute for Sustainable Development) in the UMR 152 PharmaDev research unit based in Toulouse, France. He graduated from the School of Pharmacy at Paris Descartes University in France, and he obtained his Ph.D. degree in Pharmacology at the Paul Sabatier University in Toulouse, France. He was a postdoctoral fellow specializing in the study of anti-infective medicinal plants at Emory University in Atlanta, GA in the United States. He is currently working in the field of ethnopharmacology, developing ethnobotanical and pharmacological tools to validate the use of traditional remedies.

Affiliations and Expertise

Researcher, Faculty of Pharmacy, IRD - Paul Sabatier University, Toulouse, France

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