Medicinal Plant Research in Africa

Medicinal Plant Research in Africa

Pharmacology and Chemistry

1st Edition - June 19, 2013

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  • Editor: Victor Kuete
  • eBook ISBN: 9780124059368

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Description

The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities.

Key Features

  • The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites
  • This book explores the essence of natural substances from African medicinal plants and their pharmacological potential
  • The authors are world reknowned African Scientists

Readership

Students and scientists in the field of Chemistry, phytochemistry, pharmacology, medicine, pharmacognosy, pharmaceutical biology

Table of Contents

  • About the Editor

    Preface

    List of Contributors

    1. Monoterpenes and Related Compounds from the Medicinal Plants of Africa

    1.1 Introduction

    1.2 Biosynthesis and Structural Diversity

    1.3 Monoterpenes Isolated from African Medicinal Plants and Their Pharmacological Activities

    1.4 New Monoterpenes Isolated in African Medicinal Plants

    1.5 Other Monoterpenes in African Medicinal Plants

    1.6 Conclusion

    References

    2. Sesquiterpenes from the Medicinal Plants of Africa

    2.1 Introduction

    2.2 Biosynthesis and Structural Diversity

    2.3 Pharmacological Activities of Sesquiterpenes Isolated from African Medicinal Plants

    2.4 New Sesquiterpenes Isolated from Medicinal Plants of Africa

    2.5 Other Sesquiterpenes in Medicinal Plants of Africa

    2.6 Conclusion

    References

    3. Diterpenoids from the Medicinal Plants of Africa

    3.1 Introduction

    3.2 Biosynthesis and Structural Diversity

    3.3 Nomenclature and Identification of Diterpenoids

    3.4 Pharmacological Activities of Diterpenoids Isolated from African Medicinal Plants

    3.5 Conclusions

    References

    4. Triterpenes and Steroids from the Medicinal Plants of Africa

    4.1 Introduction

    4.2 Biosynthesis and Structural Diversity

    4.3 Phytochemical Detection of Triterpenoids and NMR Identification

    4.4 Nomenclature of Triterpenoids

    4.5 New Triterpenoids Isolated from African Medicinal Plants

    4.6 Triterpene and Steroids Isolated from African Medicinal Plants and Their Pharmacological Activities

    4.7 Other Triterpenoids from African Medicinal Plants

    4.8 Conclusions

    References

    5. Essential Oils from the Medicinal Plants of Africa

    5.1 Introduction

    5.2 Classification of Essential Oils

    5.3 Chemical Composition of Essential Oils

    5.4 Biological Activity of Essential Oils from African Medicinal Plants

    5.5 Conclusion

    References

    6. Simple Phenols, Phenolic Acids, and Related Esters from the Medicinal Plants of Africa

    6.1 Introduction

    6.2 Biosynthesis of Phenolic Compounds and Structural Diversity

    6.3 Simple Phenols, Phenolic Acids, and Related Ethers Isolated from African Medicinal Plants and Their Pharmacological Activities

    6.4 New Simple Phenols, Phenolic Acids, and Related Ethers Isolated in African Medicinal Plants

    6.5 Other Simple Phenols, Phenolic Acids, and Related Ethers in African Medicinal Plants

    6.6 Conclusions

    References

    7. Phenylpropanoids and Related Compounds from the Medicinal Plants of Africa

    7.1 Introduction

    7.2 Biosynthesis of Phenylpropanoids and Structural Diversity

    7.3 Phenylpropanoids Isolated from African Medicinal Plants and Their Pharmacological Activity

    7.4 New Phenylpropanoids Isolated in African Medicinal Plants

    7.5 Conclusion

    References

    8. Coumarins and Related Compounds from the Medicinal Plants of Africa

    8.1 Introduction

    8.2 Biosynthesis and Structural Diversity

    8.3 Detection of Coumarin in Plant Extracts

    8.4 Pharmacological Activity of Coumarins Isolated from African Medicinal Plants

    8.5 New Coumarins Isolated in African Medicinal Plants

    8.6 Other Coumarins in African Medicinal Plants

    8.7 Coumarin-Related Compounds from African Medicinal Plants

    8.8 Conclusion

    References

    9. Flavonoids and Related Compounds from the Medicinal Plants of Africa

    9.1 Introduction

    9.2 Biosynthesis and Structural Diversity

    9.3 Characterization of Flavonoids in Plant Extracts

    9.4 Pharmacological Activities of Flavonoids and Related Compounds Isolated from African Medicinal Plants

    9.5 Flavonoids and Related Compounds Newly Identified in African Medicinal Plants

    9.6 Conclusions

    References

    10. Quinones and Benzophenones from the Medicinal Plants of Africa

    10.1 Introduction

    10.2 Biosynthesis and Structural Diversity

    10.3 Quinones and Benzophenones Isolated from African Medicinal Plants

    10.4 Benzophenones Identified in African Medicinal Plants

    10.5 Structural Elucidation of Quinones

    10.6 Conclusion

    References

    11. Xanthones and Anthranoids from the Medicinal Plants of Africa

    11.1 Introduction

    11.2 Biosynthesis and Structural Diversity

    11.3 Characterization of Xanthones and Anthrones in Plants

    11.4 Xanthones Isolated from African Medicinal Plants and Their Pharmacological Activities

    11.5 Pharmacological Activities of Anthrones Identified in African Medicinal Plants

    11.6 Some Particular Aspects of New Xanthones Isolated in African Medicinal Plants

    11.7 Other Xanthones Identified in African Medicinal Plants

    11.8 Conclusion

    References

    12. Lignans and Stilbenes from African Medicinal Plants

    12.1 Introduction

    12.2 Biosynthesis of Lignans and Stilbenes

    12.3 Diversity of Lignans and Stilbenes

    12.4 Pharmacological Activity of Lignans and Stilbenes Isolated from African Medicinal Plants

    12.5 New Lignans with Undefined Pharmacological Activity Isolated in African Medicinal Plants

    12.6 Stilbenes from African Medicinal Plants with Undefined Pharmacological Activity

    12.7 Other Lignans Identified in African Medicinal Plants

    Conclusion

    References

    13. Tannins and Related Compounds from Medicinal Plants of Africa

    13.1 Introduction

    13.2 Biosynthesis and Structural Diversity

    13.3 Pharmacological Activity of Tannins and Their Monomers Isolated from African Medicinal Plants

    13.4 New Tannins Isolated in African Medicinal Plants

    13.5 Other Tannins or Tannin Monomers from African Medicinal Plants

    References

    14. Alkaloids from the Medicinal Plants of Africa

    14.1 Introduction

    14.2 Biosynthesis and Structural Diversity

    14.3 Detection of Alkaloids

    14.4 Pharmacological Activity of Alkaloids Isolated from African Medicinal Plants

    14.5 Some Particular Aspects of New Alkaloids Isolated in African Medicinal Plants

    14.6 Conclusion

    References

    15. Ceramides, Cerebrosides, and Related Long Chains Containing Derivatives from the Medicinal Plants of Africa

    15.1 Introduction

    15.2 Biosynthesis and Structural Diversity

    15.3 Structure Elucidation and Nomenclature of Ceramides

    15.4 Pharmacological Activity of Ceramides and Cerebrosides Isolated from African Medicinal Plants

    15.5 New Ceramides and Cerebrosides Isolated in African Medicinal Plants

    15.6 Conclusions

    References

    16. Antibacterial, Antifungal, and Antiviral Activities of African Medicinal Plants

    16.1 Introduction

    16.2 Distribution and Diversity

    16.3 Antibacterial Activity

    16.4 Antifungal Activity

    16.5 Antiviral Activity

    16.6 Concluding Remarks

    Acknowledgment

    References

    17. Antimalarial and Other Antiprotozoal Products from African Medicinal Plants

    17.1 Introduction

    17.2 The Costs of Malaria and Other Protozoan Diseases to the African Population

    17.3 Pharmacological Activity of Medicinal Plants

    17.4 Antiprotozoal Herbal Medicine from African Medicinal Plants: Clinical Safety and Efficacy Research

    17.5 The Way Forward

    17.6 Conclusion

    References

    18. Antiproliferative Potential of African Medicinal Plants

    18.1 Introduction

    18.2 Cancer Concern in Africa

    18.3 Cytotoxicity of African Medicinal Plants

    18.4 Mechanistic Studies with Cytotoxic Natural Products of African Medicinal Plants

    18.5 Conclusions

    References

    19. Anti-Inflammatory and Analgesic Activities of African Medicinal Plants

    19.1 Introduction

    19.2 Medicinal Plants with Anti-Inflammatory and Analgesic Activities

    19.3 Conclusion

    References

    20. Antidiabetes Activity of African Medicinal Plants

    20.1 Introduction

    20.2 Diabetes Worldwide and in Africa

    20.3 Pharmacological Activities of Medicinal Plants

    20.4 Conclusion

    References

    21. Antioxidant Activity of African Medicinal Plants

    21.1 Introduction

    21.2 Sources of Antioxidants

    21.3 African Medicinal Plants with Antioxidant Potential

    21.4 Conclusions

    References

    22. African Medicinal Plants Acting on the Reproductive, Cardiovascular, and Central Nervous Systems

    22.1 Introduction

    22.2 African Traditional Medicine

    22.3 Pharmacological Activities of Medicinal Plants

    22.4 Conclusion

    References

    23. Legislation on Medicinal Plants in Africa

    23.1 Introduction

    23.2 The Status of Medicinal Plants in Some African Countries

    23.3 Legislation in the Areas of Medicinal Plants

    23.4 Conclusions

    References

    24. Medicinal Plants Market and Industry in Africa

    24.1 Introduction

    24.2 Current Status and Trend in Medicinal Plant Resources in Africa

    24.3 Trade and Marketing

    24.4 Phytopharmaceutical Manufacturing Companies

    24.5 Supply of Medicinal Plants in Africa

    24.6 Overview of Local Trade in Some Selected African Countries

    24.7 Medicinal Plant Products Industry and Manufacturing

    24.8 Conclusions

    References

Product details

  • No. of pages: 916
  • Language: English
  • Copyright: © Elsevier 2013
  • Published: June 19, 2013
  • Imprint: Elsevier
  • eBook ISBN: 9780124059368

About the Editor

Victor Kuete

Victor Kuete
Dr. Victor Kuete is a scholar-scientist at the University of Dschang, Cameroon. Dr. Kuete has been a fellow of TWAS (2007), AUF (2008), DAAD (2009), University of Mainz-Germany (2010), Alexander von Humboldt (2012-2014), etc., and International Foundation for Science Grantee (2008-2009; 2012-2013). His Research Programme is focused on Pharmacognosy and Dr. Kuete mainly investigates African medicinal plants and isolated compounds as potential antimicrobial, antiviral, anti-proliferative agents. Dr. Kuete is the author of more than 120 scientific publications related to the bioactivity of medicinal plants and their derived products, and has also authored several books and more than forty book chapters.

Affiliations and Expertise

Department of Biochemistry, Faculty of Sciences, University of Dschang, Cameroon

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